Straight thinking on narcotics: alcohol, tobacco, opium, morphine, cocaine, and marihuana.

Bibliography: 165-171.

A study of international control of narcotics and dangerous drugs

"Final report, BNDD contract no. 71-28."

An evaluation of the Cook County State's Attorney's Office Narcotics Nuisance Abatement Unit /

At head of title: Research and program evaluation in Illinois: studies on drug abuse and violent crime.

International narcotics control update.

Caption title.

Physiology for the young. Our bodies; or, How we live. An elementary text-book of physiology and hygiene for use in the common schools, with special reference to the effects of stimulants and narcotics on the human system,

Published also under title: Our bodies and how we live.

Drugs, law enforcement, and foreign policy : hearings before the Subcommittee on Terrorism, Narcotics, and International Communications and International Economic Policy, Trade, Oceans, and Environment of the Committee on Foreign Relations, United States Senate, One Hundredth Congress, first session.

"February 8, 9, 10, and 11, 1988"--Pt. 2.

The BCCI affair : hearings before the Subcommittee on Terrorism, Narcotics, and International Operations of the Committee on Foreign Relations, United States Senate, One Hundred Second Congress, first session ...

Shipping list no.: 92-126-P (pt. 1), 92-138-P (pt. 2), 92-137-P (pt. 3).

Revocation or denial of seamen's documents to narcotic law violators. Hearing before a subcommittee of the Committee on Interstate and Foreign Commerce, United States Senate, Eighty-third Congress, second session, on H. R. 8538, an act to provide for the revocation or denial of Merchant Marine documents to persons involved in certain narcotics violations. June 16, 1954.

Mode of access: Internet.

Drug Control : U.S. international narcotics control activities :report to the Congress /

"B-225282."

Illicit narcotics traffic.

Mode of access: Internet.

Organized crime and illicit traffic in narcotics : hearings ... Eighty-eighth Congress, first session pursuant to Senate Resolution 17, 88th Congress.

Includes index--pt. 6.

Applied physiology : including the effects of alcohol and narcotics /

Includes index.

School-based drug prevention programs: a review of what works

This article examines the effectiveness of school-based drug prevention programs in preventing illicit drug use. Our article reports the results of a systematic review of the evaluation literature to answer three fundamental questions: (1) do school-based drug prevention programs reduce rates of illicit drug use? (2) what features are characteristic of effective programs? and (3) do these effective program characteristics differ from those identified as effective in reviews of school-based drug prevention of licit substance use (such as alcohol and tobacco)? Using systematic review and meta-analytic techniques, we identify the characteristics of schoolbased drug prevention programs that have a significant and beneficial impact on ameliorating illicit substance use (i.e., narcotics) among young people. Successful intervention programs typically involve high levels of interactivity, time-intensity, and universal approaches that are delivered in the middle school years. These program characteristics aligned with many of the effective program elements found in previous reviews exploring the impact of school-based drug prevention on licit drug use. Contrary to these past reviews, however, our analysis suggests that the inclusion of booster sessions and multifaceted drug prevention programs have little impact on preventing illicit drug use among school-aged children. Limitations of the current review and policy implications are discussed.

A qualitative investigation of drug use among Pakistani road users

Background Statistics on drug use by Pakistani drivers are not available, yet considerable numbers of drivers are believed to be drug addicted. The National Drug Abuse Assessment 2006/07, conducted by the United Nation Office on Drugs and Crime and the Ministry of Narcotics Control Pakistan reported that opiate users numbered 628,000, of which 77%were chronic heroin abusers. Injecting drug users have reportedly doubled in the decade to 2006 and drug use has been linked with many major crashes involving professional drivers. Aims This study explored a broad range of risk taking behaviours of road users, including drug use. It also investigated associations between risky road use and fatalism and other cultural beliefs. Methods This paper reports findings relating to drug driving in the cities of Lahore, Rawalpindi and Islamabad. Thirty semi-structured interviews were conducted with bus, truck, and taxi drivers, policy makers and field police officers. Results Interviews suggested widespread use of illicit drugs, particularly among bus, truck and taxi drivers. Reasons for drug use included recreational purposes, stimulants during long driving episodes, and substance addiction. Furthermore, the use of drugs and any association with road crashes was generally viewed as linked to fatalism rather than to any fault of an individual. In other words, people did not believe there was an association between drug use and road crashes, even if they had personally experienced such. Police knowledge of drug use among drivers was evident, although there is no formal drug driving testing regime in Pakistan. Discussion and conclusions The substantial increase in drug use among the population in recent years highlights a significant public health challenge in Pakistan. This qualitative research, although recognized as not representative of the broader population, suggests that there is significant cause for concern about drug driving, especially among professional drivers, and a need for further investigation and intervention.

Orexin/hypocretin role in reward: implications for opioid and other addictions

Addiction is a devastating disorder that affects 15.3 million people worldwide. While prevalent, few effective treatments exist. Orexin receptors have been proposed as a potential target for anti-craving medications. Orexins, also known as hypocretins, are neuropeptides produced in neurons of the lateral and dorsomedial hypothalamus and perifornical area, which project widely throughout the brain. The absence of orexins in rodents and humans leads to narcolepsy. However, orexins also have an established role in reward seeking. This review will discuss some of the original studies describing the roles of the orexins in reward seeking as well as specific works that were presented at the 2013 International Narcotics Research Conference. Orexin signalling can promote drug-induced plasticity of glutamatergic synapses onto dopamine neurons of the ventral tegmental area (VTA), a brain region implicated in motivated behaviour. Additional evidence suggests that orexin signalling can also promote drug seeking by initiating an endocannabinoid-mediated synaptic depression of GABAergic inputs to the VTA, and thereby disinhibiting dopaminergic neurons. Orexin neurons co-express the inhibitory opioid peptide dynorphin. It has been proposed that orexin in the VTA may not mediate reward per se, but rather occludes the ‘anti-reward’ effects of dynorphin. Finally, orexin signalling in the prefrontal cortex and the central amygdala is implicated in reinstatement of reward seeking. This review will highlight recent work describing the role of orexin signalling in cellular processes underlying addiction-related behaviours and propose novel hypotheses for the mechanisms by which orexin signalling may impart drug seeking.