风险认知的心理学研究

This research uses a multitask, multimodel approach to probe teh problem of risk perception. It consists of three parts. First, the research of risk perception in general social circumstances, the aim is to collect information about the risk perceived by popular; Secondly, the research of risk perception under working circumstances, in the form of questionaire on enterprises; Thirdly, an experimental test of risk cognitive strategies by computer simulation, that is 2x2x3 design of laboratory research based on questionaire.

Mehrzweckschutzrelais für Mittelspannungsnetze unter Berücksichtigung von Stationsleitsystemen

Ein universell verwendbares Mehrzweckschutzrelais (MZR)wird vorgestellt, dessen Schutzfunktionen ausschließlich durch Software bestimmt sind. Mit dem MZR wird nachgewiesen, daß die vorhandene Typenvielfalt von Schutzrelais für Mittelspannungsnetze auf einen Grundtypus reduziert werden kann. Das MZR kann in Stationsleitsysteme eingebunden werden. Die Schutzfunktionen des MZR sind Überstromschutz (MZR-I), Distanzschutz (MZR-Z) und Differentialschutz (MZR-D). Ergänzend werden ausgeführt thermisches Abbild, Erdschlußerkennung, Erdschlußrichtungsbestimmung, Kurzunterbrechung und Betriebsmeßtechnik. Für jede Schutzfunktion wurde ein spezielles Programmsegment erstellt. Je nach Komplexität der Schutzaufgabe übernimmt ein Signalprozessor bestimmte Aufgaben im MZR, wie z.B. digitale Filterung der Meßsignale, Impedanzbestimmung, Diskrete Fouriertransformation, Bestimmung des Mitsystems nach dem Verfahren der symmetrischen Komponenten. Die von der Schutzfunktion unabhängigen Programmbestandteile sind zu einem echtzeitfähigen Multitask-Betriebssystem zusammengefaßt. Ein kostengünstiges MZR-Modul zur Speicherung von Störungsereignissen wird als Erweiterung gegenüber konventionellen Schutzrelais vorgestellt. Hiermit können vom MZR erkannte Störungen achtkanalig erfaßt und mit Echtzeitmarken versehen auf Disketten im standardisierten AufZeichnungsformat gespeichert werden. Ein neues Verfahren zur Simulation des Meßverhaltens der erstellten MZR-Varianten mit dem Programm "EMTP" auf einem Personalcomputer der AT—Klasse wurde entwickelt.

Caractérisation de nouveaux mécanismes transcriptionnels impliqués dans la biologie osseuse

Le développement et l'homéostasie des os requièrent l'orchestration spatio-temporelle d'un grand nombre de signaux moléculaires. Ces signaux entraînent l'activation ou l'inhibition de différents facteurs de transcription, lesquels sont en mesure de contrôler la prolifération et la différenciation des ostéoblastes et des chondrocytes. L'intégrité de ces différents mécanismes se doit d'être maintenu tout au long de la vie. Ainsi, une anomalie dans l'un de ces mécanismes conduit à l'apparition de pathologies osseuses et métaboliques telles qu’une hypophosphatémie, l'ostéoporose ou l'ostéoarthrite (OA). Afin d'en apprendre davantage sur la biologie osseuse, le projet décrit dans cette thèse a pour objectif de caractériser de nouveaux mécanismes de régulation transcriptionnelle pour deux gènes importants dans le développement des os et le maintien de leur intégrité. Il s’agit du Paired-like Homeodomain Transcription Factor 1 (PITX1) et du Phosphate-regulating gene with homology to endopeptidase on the X chromosome (PHEX). Le premier mécanisme présenté dans cette thèse concerne la régulation transcriptionnelle du gène PITX1, un facteur de transcription à homéodomaine nécessaire, notamment, au développement des os des membres inférieurs et au maintien de l'intégrité du cartilage articulaire chez l'adulte. Ainsi, dans les chondrocytes articulaires, on note que l'expression de PITX1 est assurée par le recrutement du facteur de transcription E2F1 à deux éléments de réponse présents dans la région proximale du promoteur de PITX1. Aussi, dans les chondrocytes articulaires de patients souffrant d'OA, dans lesquels l'expression de PITX1 est fortement diminuée, un mécanisme de répression transcriptionnelle, lequel implique la protéine multifonctionnelle Prohibitin (PHB1), semble être activé. En effet, dans ces chondroytes, on note une forte accumulation nucléaire de PHB1 comparativement aux chondrocytes articulaires de sujets sains. Le second mécanisme présenté dans cette thèse concerne la répression transcriptionnelle de PHEX, la peptidase mutée dans le syndrome d'hypophosphatémie lié au chromosome X (X-Linked Hypophosphatemia, XLH), lequel se caractérise par une hypophosphatémie et une ostéomalacie. Le traitement d'ostéoblastes à la Parathyroid hormone-related protein (PTHrP) permet d’observer la répression de PHEX. Afin de caractériser le mécanisme responsable de cette répression, des expériences de gènes rapporteurs ont révélé la présence de deux éléments de réponse pour le répresseur transcriptionnel E4BP4 dans le promoteur de PHEX. La suppression de l'expression d'E4BP4 par l'utilisation d'ARN d'interférence a permis de valider que ce facteur de transcription est responsable de la répression de PHEX suite au traitement d'ostéoblastes à la PTHrP. En somme ces nouveaux mécanismes de régulation transcriptionnelle permettent de mieux comprendre la régulation de l'expression de PITX1 et de PHEX. Aussi, cette nouvelle implication de PHB1 dans la pathogenèse de l'OA offre de nouvelles possibilités de traitement et pourrait servir pour le diagnostic précoce de cette pathologie. Enfin, la caractérisation d'E4BP4 en tant que médiateur pour la répression de PHEX par la PTHrP suggère que ce répresseur transcriptionnel pourrait être impliqué dans le contrôle de la minéralisation des os et des niveaux de phosphate sanguin.

Du Linéaire au Stellaire, du film au webdocumentaire : un dispositif de réflexion et de communication sur le réel

Ce texte de mémoire est accompagné du webdocumentaire interactif : De la chaise à la mer, disponible à l'adresse http://www.delachaisealamer.net.

Partial decentralization as a safeguard against favoritism

In this paper I investigate the optimal level of decentralization of tasks for the provision of a local public good. I enrich the well-known trade-off between internalization of spillovers (that favors centralization) and accountability (that favors decentralization) by considering that public goods are produced through multiple tasks. This adds an additional institutional setting, partial decentralization, to the classical choice between full decentralization and full centralization. The main results are that partial decentralization is optimal when both the variance of exogenous shocks to electorate’s utility is large and the electorate expects high performance from politicians. I also show that the optimal institutional setting depends on the degree of substitutability / complementarity between tasks. In particular, I show that a large degree of substitutability between tasks makes favoritism more likely, which increases the desirability of partial decentralization as a safeguard against favoritism.

Analysis of functional networks involved in motor execution and motor imagery using combined hierarchical clustering analysis and independent component analysis

Cognitive experiments involving motor execution (ME) and motor imagery (MI) have been intensively studied using functional magnetic resonance imaging (fMRI). However, the functional networks of a multitask paradigm which include ME and MI were not widely explored. In this article, we aimed to investigate the functional networks involved in MI and ME using a method combining the hierarchical clustering analysis (HCA) and the independent component analysis (ICA). Ten right-handed subjects were recruited to participate a multitask experiment with conditions such as visual cue, MI, ME and rest. The results showed that four activation clusters were found including parts of the visual network, ME network, the MI network and parts of the resting state network. Furthermore, the integration among these functional networks was also revealed. The findings further demonstrated that the combined HCA with ICA approach was an effective method to analyze the fMRI data of multitasks.

Regularized nonnegative shared subspace learning

Joint modeling of related data sources has the potential to improve various data mining tasks such as transfer learning, multitask clustering, information retrieval etc. However, diversity among various data sources might outweigh the advantages of the joint modeling, and thus may result in performance degradations. To this end, we propose a regularized shared subspace learning framework, which can exploit the mutual strengths of related data sources while being immune to the effects of the variabilities of each source. This is achieved by further imposing a mutual orthogonality constraint on the constituent subspaces which segregates the common patterns from the source specific patterns, and thus, avoids performance degradations. Our approach is rooted in nonnegative matrix factorization and extends it further to enable joint analysis of related data sources. Experiments performed using three real world data sets for both retrieval and clustering applications demonstrate the benefits of regularization and validate the effectiveness of the model. Our proposed solution provides a formal framework appropriate for jointly analyzing related data sources and therefore, it is applicable to a wider context in data mining.

Multitasking: multiple, domain-specific cognitive functions in a virtual environment

Multitasking among three or more different tasks is a ubiquitous requirement of everyday cognition, yet rarely is it addressed in research on healthy adults who have had no specific training in multitasking skills. Participants completed a set of diverse subtasks within a simulated shopping mall and office environment, the Edinburgh Virtual Errands Test (EVET). The aim was to investigate how different cognitive functions, such as planning, retrospective and prospective memory, and visuospatial and verbal working memory, contribute to everyday multitasking. Subtasks were chosen to be diverse, and predictions were derived from a statistical model of everyday multitasking impairments associated with frontal-lobe lesions (Burgess, Veitch, de Lacy Costello, & Shallice, 2000b). Multiple regression indicated significant independent contributions from measures of retrospective memory, visuospatial working memory, and online planning, but not from independent measures of prospective memory or verbal working memory. Structural equation modelling showed that the best fit to the data arose from three underlying constructs, with Memory and Planning having a weak link, but with both having a strong directional pathway to an Intent construct that reflected implementation of intentions. Participants who followed their preprepared plan achieved higher scores than those who altered their plan during multitask performance. This was true regardless of whether the plan was efficient or poor. These results substantially develop and extend the Burgess et al. (2000b) model to healthy adults and yield new insight into the poorly understood area of everyday multitasking. The findings also point to the utility of using virtual environments for investigating this form of complex human cognition.

Factorial multi-task learning : a Bayesian nonparametric approach

Multi-task learning is a paradigm shown to improve the performance of related tasks through their joint learning. However, for real-world data, it is usually difficult to assess the task relatedness and joint learning with unrelated tasks may lead to serious performance degradations. To this end, we propose a framework that groups the tasks based on their relatedness in a subspace and allows a varying degree of relatedness among tasks by sharing the subspace bases across the groups. This provides the flexibility of no sharing when two sets of tasks are unrelated and partial/total sharing when the tasks are related. Importantly, the number of task-groups and the subspace dimensionality are automatically inferred from the data. To realize our framework, we introduce a novel Bayesian nonparametric prior that extends the traditional hierarchical beta process prior using a Dirichlet process to permit potentially infinite number of child beta processes. We apply our model for multi-task regression and classification applications. Experimental results using several synthetic and real datasets show the superiority of our model to other recent multi-task learning methods. Copyright 2013 by the author(s).

Desenho de incentivos na presença de objetivos múltiplos

Uma hipótese central nos modelos de relação agente-principal é a de que o principal busca maximizar o lucro. O objetivo do trabalho é estudar a provisão de incentivos quando o principal possui múltiplos objetivos além da maximização do lucro e o uso de medidas adicionais de performance é custoso. O modelo apresentado é uma modificação do modelo de multitask proposto por Holmström e Milgrom (1991). Como resultados, observa-se que a forma do contrato ótimo é sensível à correlação entre os ruídos das medidas de performance e que tanto um principal que se preocupa muito com o objetivo adicional, quanto um principal que se preocupa muito com o produto da firma, estarão dispostos a pagar o custo de observação da medida de performance adicional quando a correlação entre os ruídos é positiva.

Med Capital Partners: plan de negocio de una EAFI

Med Capital Partners (MCP en adelante) es un empresa de asesoramiento financiero independiente (EAFI) que ofrecerá servicios de asesoramiento personalizado tanto a clientes particulares como a empresas, complementando su oferta con otros servicios auxiliares, que le permitan brindar a sus clientes una solución integral. MCP ha sido fundada por tres socios con formación y experiencia específica en el ámbito objeto del negocio, pero multidisciplinar para ofrecer un amplio espectro de servicios de calidad tanto en la Región de Murcia, donde va a establecer su sede, como en el resto de territorio nacional. MCP se crea con la firme misión de ofrecer servicios de asesoramiento y consulta financieros para la gestión y planificación patrimonial de calidad, de forma independiente y transparente y con la motivación de ser el médico de cabecera financiero de familias, particulares y empresas de todos los ámbitos, basándonos en arraigados valores entre los que predominan la transparencia, la independencia y la discreción. Una vez analizados los factores externos y haber realizado los planes de marketing, operaciones y financiero, nos encontramos en disposición de determinar que: 1.Existe un gran número de clientes potenciales. 2.Los factores político, social y legal favorecen la creación de este tipo de empresas. 3.Hay pocos competidores establecidos hasta la fecha. 4.No necesita complicadas infraestructuras ni requiere elevados gastos de aprovisionamiento. 5.Desde el año 2, se obtienen resultados positivos. La propuesta de valor de MCP está focalizada en ofrecer un servicio de calidad al menor precio posible, fijando una política de tarifas inferior a la media nacional y a la de nuestros competidores más cercanos, así como un esquema de precios descendentes para aquellos clientes que depositen su confianza en nosotros y renueven su contrato de asesoramiento continuado o contraten un combo de servicios. En términos operativos, el establecimiento de MCP requiere relativamente poco capital inicial, permitiendo ofrecer los primeros dividendos a los socios en un corto espacio temporal y teniendo desde el primer momento, un sueldo que les permita dedicarse plenamente al funcionamiento de MCP. En definitiva, creemos que MCP puede dar respuesta a una gran oportunidad de negocio existente en un sector en alza y en un mercado de arranque en el que hay una gran riqueza y poca cultura de inversión asesorada. ---ABSTRACT---Med Capital Partners (MCP) is an invest services company, which is established according to an EAFI structure. MCP will offer a custom-made service not only to individual clients but also to enterprises, with a wide range of supplementary services, including industrial strategy projects and all kind of financial processes demanded. MCP has been founded by three partners with proved training and specific experience based on the financial field but multitask and different between them, in order to offer various quality services in Región de Murcia, where it is going to be based, and also all around Spain. MCP is built with the firm mission of offering assessment and financial consulting quality services, helping with the patrimonial management and planning, doing it in an independent and transparent way, and always driving by the motivation of being the family doctor of individual and enterprise of sectors. To make it possible, MCP has deep values as excellence, wisdom and discretion. Once we have analyzed external factors and having made marketing, operations and financial plans, we are ready to determinate: 1.There is a big amount of potential customers. 2.Political, social and legal factors favor the formation of this type of business. 3.There are not many established competitors until now. 4.MCP does not need complex infrastructures either raised initial investment. 5.From year 2 and on, MCP is profitable. The value proposition of MCP is to focus on developing quality services with affordable fees, fixing a price policy under any other Spanish EAFI. MCP wants to build processes according to reality, working with reachable expectations and on real times. MCP is committed to the creation of stable, sustainable and consistent structures to adapt themselves to the individual risk profile of the customers, taking care of all of them. MCP wants to build a close relationship with clients and has developed a descending fee policy. MCP establishment does not require high initial resources and it is profitable in a short time, allowing investors to get their first dividends. Summarizing, we can say MCP is the answer of a big business opportunity within a rising and wealth market that only need a little help to emerge.

Instalación de un sistema funcional sobre un computador convencional

En esta tesis se tratan dos aspectos fundamentales de los sistemas funcionales, de cuyo tratamiento depende, en gran medida, la eficiencia de tales sistemas. En primer lugar, se presentan y evalúan una serie de soluciones al problema de representación interna en los sistemas funcionales, soluciones basadas en la utilización de estructuras lineales para obtener una mejora en el tiempo de ejecución y en la ocupación de la memoria del sistema. En segundo lugar, se presenta un sistema de evaluación multitarea para reducir programas funcionales, basado en la especificación de varios ficheros de salida. En él, las tareas del sistema evalúan, de forma concurrente, las diversas partes del resultado de un programa y se .comunican entre sí en base a mensajes que permiten detectar y resolver, sin necesidad de abortar la ejecución, bucles de dependencias entre tareas. El sistema reacciona ante estas situaciones de error de forma comedida, de modo que este error no afecta al resto de las tareas del sistema. Se plantea también un mecanismo de gestión de memoria, mecanismo que introduce una tarea especial en el sistema, encargada de la gestión de una memoria común a todo él, y satisface las necesidades de memoria de las tareas de forma, transparente al mecanismo de evaluación.---ABSTRACT---Two fundamental aspects of functional systems, of which their efficiency to a large extent depends, are dealt with in this thesis. Firstly, several solutions to the internal representation problem of functional systems are proposed and evaluated. These solutions are based on the use of linear data structures in order to achieve a shorter execution time and smaller memory requirement. Secondly, a new multitask evaluation system for the reduction of functional programs is described; it is based on the specifücation of several output files. In this evaluation system, the task evaluates in the different parts of the program result concurrently. Tasks communicate one another through messages, which make it possible to detect and solve the dependency loops within tasks. The program does not need to be aborted, the sistem reacts to such error situations in a smooth way, no other tasks are affected. A memory management system is also introduced. This management system inserts a special task, that carries-out the management of a common memory and serves all tasks memory requirements in a transparent mode to the evaluation mechanism.

ESTUDO COMPARATIVO DA COMPETITIVIDADE DAS EMPRESAS DE MÁQUINAS FERRAMENTAS BRASILEIRAS: ANÁLISE MULTICRITÉRIOS

O principal objetivo desta dissertação foi analisar por meio de estudo comparativo, o posicionamento competitivo de três máquinas ferramentas multitarefas. As hipóteses iniciais partiram das seguintes suposições: a) a indústria nacional de máquinas ferramentas esta sendo penalizada pela política industrial praticada pelo governo federal; e b) a importância relativa atribuída aos elementos multicriteriais das especificações das máquinas nacionais quando demonstram tendências elevadas, nem sempre alcançam as concorrentes importadas devido aos recursos tecnológicos agregados para se atingir a competitividade plena. Assim, indaga-se: até que ponto as máquinas ferramentas multitarefas selecionadas para o estudo, estão alinhadas com os critérios escolhidos e com suas importâncias relativas avaliadas por dois usuários desse equipamento. Como metodologia adotou-se estudo de caso múltiplo de duas empresas de médio porte do mesmo ramo. Utilizou-se o método multicritério de apoio à decisão por meio de Analytic Hierarchy Process (AHP), para a escolha da melhor alternativa entre máquinas ferramentas multitarefas similares, nacionais e importadas. Os resultados identificam que, para essas duas empresas usuárias pesquisadas, existe vantagem na aquisição da máquina importada, embora seja notório o avanço tecnológico da indústria nacional. Estas máquinas ainda carecem de algumas inovações, perdendo em competitividade, bem como em critérios importantes como versatilidade e rendimento. Com base nos trabalhos, conclui-se que, as máquinas ferramentas do tipo multitarefas nacionais das duas empresas fornecedoras analisadas não são competitivas em comparação as importadas.

ESTUDO COMPARATIVO DA COMPETITIVIDADE DAS EMPRESAS DE MÁQUINAS FERRAMENTAS BRASILEIRAS: ANÁLISE MULTICRITÉRIOS

O principal objetivo desta dissertação foi analisar por meio de estudo comparativo, o posicionamento competitivo de três máquinas ferramentas multitarefas. As hipóteses iniciais partiram das seguintes suposições: a) a indústria nacional de máquinas ferramentas esta sendo penalizada pela política industrial praticada pelo governo federal; e b) a importância relativa atribuída aos elementos multicriteriais das especificações das máquinas nacionais quando demonstram tendências elevadas, nem sempre alcançam as concorrentes importadas devido aos recursos tecnológicos agregados para se atingir a competitividade plena. Assim, indaga-se: até que ponto as máquinas ferramentas multitarefas selecionadas para o estudo, estão alinhadas com os critérios escolhidos e com suas importâncias relativas avaliadas por dois usuários desse equipamento. Como metodologia adotou-se estudo de caso múltiplo de duas empresas de médio porte do mesmo ramo. Utilizou-se o método multicritério de apoio à decisão por meio de Analytic Hierarchy Process (AHP), para a escolha da melhor alternativa entre máquinas ferramentas multitarefas similares, nacionais e importadas. Os resultados identificam que, para essas duas empresas usuárias pesquisadas, existe vantagem na aquisição da máquina importada, embora seja notório o avanço tecnológico da indústria nacional. Estas máquinas ainda carecem de algumas inovações, perdendo em competitividade, bem como em critérios importantes como versatilidade e rendimento. Com base nos trabalhos, conclui-se que, as máquinas ferramentas do tipo multitarefas nacionais das duas empresas fornecedoras analisadas não são competitivas em comparação as importadas.

ESTUDO COMPARATIVO DA COMPETITIVIDADE DAS EMPRESAS DE MÁQUINAS FERRAMENTAS BRASILEIRAS: ANÁLISE MULTICRITÉRIOS

O principal objetivo desta dissertação foi analisar por meio de estudo comparativo, o posicionamento competitivo de três máquinas ferramentas multitarefas. As hipóteses iniciais partiram das seguintes suposições: a) a indústria nacional de máquinas ferramentas esta sendo penalizada pela política industrial praticada pelo governo federal; e b) a importância relativa atribuída aos elementos multicriteriais das especificações das máquinas nacionais quando demonstram tendências elevadas, nem sempre alcançam as concorrentes importadas devido aos recursos tecnológicos agregados para se atingir a competitividade plena. Assim, indaga-se: até que ponto as máquinas ferramentas multitarefas selecionadas para o estudo, estão alinhadas com os critérios escolhidos e com suas importâncias relativas avaliadas por dois usuários desse equipamento. Como metodologia adotou-se estudo de caso múltiplo de duas empresas de médio porte do mesmo ramo. Utilizou-se o método multicritério de apoio à decisão por meio de Analytic Hierarchy Process (AHP), para a escolha da melhor alternativa entre máquinas ferramentas multitarefas similares, nacionais e importadas. Os resultados identificam que, para essas duas empresas usuárias pesquisadas, existe vantagem na aquisição da máquina importada, embora seja notório o avanço tecnológico da indústria nacional. Estas máquinas ainda carecem de algumas inovações, perdendo em competitividade, bem como em critérios importantes como versatilidade e rendimento. Com base nos trabalhos, conclui-se que, as máquinas ferramentas do tipo multitarefas nacionais das duas empresas fornecedoras analisadas não são competitivas em comparação as importadas.