Maj Lind 1973 : Alkuerä [Raekallio, Luolajan-Mikkola]

Soitinnus: piano.

Tietokone työvälineenä : Seppo Mustosen haastattelu

Nimekkeen selitys: Haastateltavana Helsingin yliopiston tilastotieteen professori Seppo Mustonen, joka on luonut SURVO-järjestelmän, vuorovaikutteisen tietojenkäsittelysysteemin tilastollisten analyysien suorittamiseen.

"Seppo" kaasugeneraattorin käyttö- ja hoito-ohjeet

kuv., 11 x 17 cm

Arkistoluettelo 728: Seppo Tuominen

Luettelo Kansalliskirjastossa olevan Seppo Tuomisen arkiston sisällöstä

Arkistoluettelo 163: Seppo Nummi

Luettelo Kansalliskirjastossa olevan Seppo Nummen arkiston sisällöstä

Recent advances in the pathology of alcoholic myopathy

This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Victor R. Preedy and Junko Adachi. The presentations were (1) Alcoholic myopathy: Past, present and future, by Timothy J. Peters and Victor R. Preedy; (2) Protein adducts in the type I and II fiber-predominant muscles of the ethanol-fed rat, by Simon Worrall, Seppo Parkkila, and Onni Niemela; (3) Hydroperoxides and changes in alcoholic myopathy, by Junko Adachi, Migiwa Asamo, and Yasuhino Ueno; and (4) A close association between testicular atrophy, muscle atrophy, and the increase in protein catabolism after chronic ethanol administration, by Kunihiko Takeda, Masayoshi Yamauchi, Kazuhiko Sakamoto, Masaru Takagi, Hisato Nakajima, and Gotaro Toda.

Free radicals in alcoholic myopathy: Indices of damage and preventive studies

Chronic alcoholic myopathy affects up to two-thirds of all alcohol misusers and is characterized by selective atrophy of Type If (glycolytic, fast-twitch, anaerobic) fibers. In contrast, the Type I fibers (oxidative, slow-twitch, aerobic) are relatively protected. Alcohol increases the concentration of cholesterol hydroperoxides and malondialdehyde-protein adducts, though protein-carbonyl concentration levels do not appear to be overtly increased and may actually decrease in some studies. In alcoholics, plasma concentrations of a-tocopherol may be reduced in myopathic patients. However, a-tocopherol supplementation has failed to prevent either the loss of skeletal muscle protein or the reductions in protein synthesis in alcohol-dosed animals. The evidence for increased oxidative stress in alcohol-exposed skeletal muscle is thus inconsistent. Further work into the role of ROS in alcoholic myopathy is clearly warranted. (C) 2002 Elsevier Science Inc.