22 resultados para Mazas
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"From the works of such representative authorities as Bach, Campagnoli, Corelli, Fiorillo, Kreutzer, Mayseder, Mozart, Rode , ROvelli, Spohr, Viotti, Baillot, Beethoven, Benda, Bohrer, Bruni, Ries, Alard, Beriot, Casorti, Dont, Ernst, Kayser, Leonard, Mazas, Paganini, Schradieck, Sevčik, Hermann, etc."-- Cover.
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Mode of access: Internet.
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Contiene: Amar es saber vencer, y el arte contra el poder (pp. 1-56) ; Viento es la dicha de amor (Zarzuela música) (pp. 57-94) ; Duendes son alcahuetes, y el espíritu Foleto (pp. 95-152) ; Duendes son alcahuetes, alias el Foleto (Segunda parte) (pp. 153-207) ; El luzero de Madrid, y divino labrador, san Isidro Labrador (pp. 208-266) ; No ay deuda que no se pague, y combidado de piedra (pp. 267-322) ; Cada uno es linage aparte, y los Mazas de Aragón (pp. 323-[377]) ; Ser fino y no parecerlo (pp. [378-430])
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Contiene: El gran chímico del mundo (Loa, Auto sacramental y entremés) (pp. 1-48) ; La xarretiera de Inglaterra, El mayor aprecio del descuido de una dama (pp. 49-99) ; El Austria en Jerusalem (pp. 100-149) ; Fieras de zelos y amor (Zarzuela) (pp. 150-179) ; El esclavo en grillos de oro (pp. 179-229) ; El sastre del campillo (pp. 230-274) ; Más vale el hombre que el nombre (pp. 275-338) ; El duelo contra su dama (pp. 339-388) / Francisco de Bances Candamo. San Bernardo Abad (pp. 389-435) ; El español más amante, y desgraciado Mazías (pp. 436-477) ; Las mesas de la Fortuna (Auto sacramental alegórico) (pp. 478-507) / Francisco de Bances Candamo, Juan de la Hoz y Mota.
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Reprints. Originally published between 1800 and 1857.
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The lactase enzyme allows lactose digestion in fresh milk. Its activity strongly decreases after the weaning phase in most humans, but persists at a high frequency in Europe and some nomadic populations. Two hypotheses are usually proposed to explain the particular distribution of the lactase persistence phenotype. The gene-culture coevolution hypothesis supposes a nutritional advantage of lactose digestion in pastoral populations. The calcium assimilation hypothesis suggests that carriers of the lactase persistence allele(s) (LCT*P) are favoured in high-latitude regions, where sunshine is insufficient to allow accurate vitamin-D synthesis. In this work, we test the validity of these two hypotheses on a large worldwide dataset of lactase persistence frequencies by using several complementary approaches. Methodology We first analyse the distribution of lactase persistence in various continents in relation to geographic variation, pastoralism levels, and the genetic patterns observed for other independent polymorphisms. Then we use computer simulations and a large database of archaeological dates for the introduction of domestication to explore the evolution of these frequencies in Europe according to different demographic scenarios and selection intensities. Conclusions Our results show that gene-culture coevolution is a likely hypothesis in Africa as high LCT*P frequencies are preferentially found in pastoral populations. In Europe, we show that population history played an important role in the diffusion of lactase persistence over the continent. Moreover, selection pressure on lactase persistence has been very high in the North-western part of the continent, by contrast to the South-eastern part where genetic drift alone can explain the observed frequencies. This selection pressure increasing with latitude is highly compatible with the calcium assimilation hypothesis while the gene-culture coevolution hypothesis cannot be ruled out if a positively selected lactase gene was carried at the front of the expansion wave during the Neolithic transition in Europe.
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SELECTOR is a software package for studying the evolution of multiallelic genes under balancing or positive selection while simulating complex evolutionary scenarios that integrate demographic growth and migration in a spatially explicit population framework. Parameters can be varied both in space and time to account for geographical, environmental, and cultural heterogeneity. SELECTOR can be used within an approximate Bayesian computation estimation framework. We first describe the principles of SELECTOR and validate the algorithms by comparing its outputs for simple models with theoretical expectations. Then, we show how it can be used to investigate genetic differentiation of loci under balancing selection in interconnected demes with spatially heterogeneous gene flow. We identify situations in which balancing selection reduces genetic differentiation between population groups compared with neutrality and explain conflicting outcomes observed for human leukocyte antigen loci. These results and three previously published applications demonstrate that SELECTOR is efficient and robust for building insight into human settlement history and evolution.