Survival and early seedling growth of conifers with different shade tolerance in a Sitka spruce spacing trial and relationship to understorey light climate

Abstract

Social stress results in altered glucocorticoid regulation and shorter survival in simian acquired immune deficiency syndrome

From early in the AIDS epidemic, psychosocial stressors have been proposed as contributors to the variation in disease course. To test this hypothesis, rhesus macaques were assigned to stable or unstable social conditions and were inoculated with the simian immunodeficiency virus. Animals in the unstable condition displayed more agonism and less affiliation, shorter survival, and lower basal concentrations of plasma cortisol compared with stable animals. Early after inoculation, but before the emergence of group differences in cortisol levels, animals receiving social threats had higher concentrations of simian immunodeficiency virus RNA in plasma, and those engaging in affiliation had lower concentrations. The results indicate that social factors can have a significant impact on the course of immunodeficiency disease. Socially induced changes in pituitary–adrenal hormones may be one mechanism mediating this relationship.

Characterization of serum amyloid A protein mRNA expression and secondary amyloidosis in the domestic duck

Secondary amyloidosis is a common disease of water fowl and is characterized by the deposition of extracellular fibrils of amyloid A (AA) protein in the liver and certain other organs. Neither the normal role of serum amyloid A (SAA), a major acute phase response protein, nor the causes of secondary amyloidosis are well understood. To investigate a possible genetic contribution to disease susceptibility, we cloned and sequenced SAA cDNA derived from livers of domestic ducks. This revealed that the three C-terminal amino acids of SAA are removed during conversion to insoluble AA fibrils. Analysis of SAA cDNA sequences from several animals identified a distinct genetic dimorphism that may be relevant to susceptibility to secondary amyloid disease. The duck genome contained a single copy of the SAA gene that was expressed in liver and lung tissue of ducklings, even in the absence of induction of acute phase response. Genetic analysis of heterozygotes indicated that only one SAA allele is expressed in livers of adult birds. Immunofluorescence staining of livers from adult ducks displaying early symptoms of amyloidosis revealed what appear to be amyloid deposits within hepatocytes that are expressing unusually high amounts of SAA protein. This observation suggests that intracellular deposition of AA may represent an early event during development of secondary amyloidosis in older birds.

Clerk's Book, A.D. 1742

Handwritten volume containing the Articles, weekly orations, and clerk's journal for the Harvard Latin Society recorded by the club's clerk, Jonathan Mayhew (Harvard AB 1744). The Articles define the Society's mission as to "improve ourselves in the knowledge of the Latin Tongue." The ten articles are signed to by ten members of the classes of 1743 and 1744. The journal which records the weekly meetings from April 14, 1742 through June 17, 1742 includes a transcription of the weekly oration in Latin; the first two entries are also translated into English. On the last page of the book, the "clerk's journal" provides a summary of each meeting with the date, the moderator, and the orators.

Annals of an Angus parish /

Includes index.

A method for the piano-forte /

Mode of access: Internet.

Complete works for pianoforte: Concertstück, pieces and variations;

Mode of access: Internet.

Institutes of natural philosophy, theoretical and practical. With some corrections; change in the order of the branches; and the addition of an appendix to the astronomical part, selected from Mr. Ewing's Practical astronomy.

"Appendix to the astronomy. Containing solar and lunar tables, with their explanation and use, and the projection of eclipses, selected from 'Ewing's Practical astronomy'": [233]-297.

An essay on the government of children : under three general heads, viz. health, manners, and education /

Mode of access: Internet.

Sermons preached to a country congregation : to which are added, a few hints for sermons, intended chiefly for the use of the younger clergy /

Pie de imp. v. 2-4: Printed by Strahan and Preston

The Annual register, or a view of the history, politics, and literature for the year ...

Mode of access: Internet.

Papers relating to Mary Queen of Scots.

Mode of access: Internet.

The speaker; or, miscellaneous pieces from the best English writers ... to which is prefixed an essay on elocution.

Mode of access: Internet.

The history of philosophy, from the earliest times to the beginning of the present century; drawn up from Brucker's Historia critica philosophiæ.

Mode of access: Internet.

French's standard drama ...

Mode of access: Internet.