Dammschnitt - Einschnitt ins Liebesleben : Auswirkungen eines Dammschnittes auf die Sexualität aus der weiblichen Perspektive

[s.c.]

Kommentierte Übersetzung des NASA-Berichtes „Pioneering Space: NASA’s Next Steps on the Path to Mars“ vom Englischen ins Deutsche

Die Bachelorarbeit besteht aus der Übersetzung des NASA-Berichtes „Pioneering Space: NASA’s Next Steps on the Path to Mars“ vom Englischen ins Deutsche und einer Textanalyse nach dem Analysemodell von Christiane Nord. Dieser Analyseansatz wird grob nach den sog. textexternen und textinternen Faktoren aufgeteilt. Zu den Besonderheiten und Herausforderungen der Übersetzung werden u.a. das hohe fachsprachliche Textniveau sowie diverse Abkürzungen und Abteilungsnamen innerhalb der NASA, die im Bericht auftauchen, gehören. Da darüber hinaus die Berichte und Kommunikation in der Weltraumszene hauptsächlich in englischer Sprache erfolgt, muss ein Kompromiss gefunden werden, um die Wörter so im Text einzubringen, dass der Textfluss nicht übertrieben gestört wird.

Kraftstoffeintrag ins Motoröl von aufgeladenen, direkteinspritzenden Ottomotoren

Otto-von-Guericke-Universität Magdeburg, Fakultät für Maschinenbau, Dissertation, 2015

Web AMPA INS Serrallarga

Aquest és un projecte web encarat a proporcionar un espai web per l'Associació de pares i mares d'un institut de secundària. Aquest espai web ha de facilitar la comunicació entre l'associació i les famílies dels alumnes, així com intentar anar integrant les gestions amb l'associació per tal de facilitar la participació i accés a tota la informació relacionada amb l'institut.

1.° Sextus Pompeius Festus de verborum significatione. — 2.° Anonymi tractatus de rhetorica et de dialectica. — 3.° Aristotelis epistola ad Alexandrum de secretis secretorum. — 4.° Senecae liber ad Galeotum de vita beata. — 5.° Oeconomicorum Aristotelis liber : interprete Leonardo Aretino. — 6.° Isidori, Hispalensis, synonyma. — 7.° Messalae Corvini ad Octavium Augustum de progenie sua breve compendium.

Colbertinus

Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity.

Cell-to-cell communication mediated by gap junctions made of Connexin36 (Cx36) contributes to pancreatic β-cell function. We have recently demonstrated that Cx36 also supports β-cell survival by a still unclear mechanism. Using specific Cx36 siRNAs or adenoviral vectors, we now show that Cx36 downregulation promotes apoptosis in INS-1E cells exposed to the pro-inflammatory cytokines (IL-1β, TNF-α and IFN-γ) involved at the onset of type 1 diabetes, whereas Cx36 overexpression protects against this effect. Cx36 overexpression also protects INS-1E cells against endoplasmic reticulum (ER) stress-mediated apoptosis, and alleviates the cytokine-induced production of reactive oxygen species, the depletion of the ER Ca(2+) stores, the CHOP overexpression and the degradation of the anti-apoptotic protein Bcl-2 and Mcl-1. We further show that cytokines activate the AMP-dependent protein kinase (AMPK) in a NO-dependent and ER-stress-dependent manner and that AMPK inhibits Cx36 expression. Altogether, the data suggest that Cx36 is involved in Ca(2+) homeostasis within the ER and that Cx36 expression is downregulated following ER stress and subsequent AMPK activation. As a result, cytokine-induced Cx36 downregulation elicits a positive feedback loop that amplifies ER stress and AMPK activation, leading to further Cx36 downregulation. The data reveal that Cx36 plays a central role in the oxidative stress and ER stress induced by cytokines and the subsequent regulation of AMPK activity, which in turn controls Cx36 expression and mitochondria-dependent apoptosis of insulin-producing cells.

Nouvelle carte routière de la France : d'après celle revue par de Simencourt indiquant les routes royales et départementales, chemins de traverse, ch[em]ins de fer et canaux navigables, avec les distances en chiffres / dressée par Frémin, géographe ; Gravé par Ch. Dyonnet ; Écrit sur acier par Ch. Simon

Échelle(s) : [ca 1:2 440 000], échelle 100 kilomètres [= 4,1 cm]

The Ins and Outs of Unemployment: A Conditional Analysis

We analyze how unemployment, job finding and job separation rates react to neutral and investment-specific technology shocks. Neutral shocks increase unemployment and explain a substantial portion of unemployment volatility; investment-specific shocks expand employment and hours worked and mostly contribute to hours worked volatility. Movements in the job separation rates are responsible for the impact response of unemployment while job finding rates for movements along its adjustment path. Our evidence qualifies the conclusions by Hall (2005) and Shimer (2007) and warns against using search models with exogenous separation rates to analyze the effects of technology shocks.

The ins and outs of unemployment: An analysis conditional on technology shocks

We analyze how unemployment, job finding and job separation rates reactto neutral and investment-specific technology shocks. Neutral shocks increaseunemployment and explain a substantial portion of it volatility; investment-specificshocks expand employment and hours worked and contribute to hoursworked volatility. Movements in the job separation rates are responsible for theimpact response of unemployment while job finding rates for movements alongits adjustment path. The evidence warns against using models with exogenousseparation rates and challenges the conventional way of modelling technologyshocks in search and sticky price models.

Genetic Variations and Diseases in UniProtKB/Swiss-Prot: The Ins and Outs of Expert Manual Curation.

During the last few years, next-generation sequencing (NGS) technologies have accelerated the detection of genetic variants resulting in the rapid discovery of new disease-associated genes. However, the wealth of variation data made available by NGS alone is not sufficient to understand the mechanisms underlying disease pathogenesis and manifestation. Multidisciplinary approaches combining sequence and clinical data with prior biological knowledge are needed to unravel the role of genetic variants in human health and disease. In this context, it is crucial that these data are linked, organized, and made readily available through reliable online resources. The Swiss-Prot section of the Universal Protein Knowledgebase (UniProtKB/Swiss-Prot) provides the scientific community with a collection of information on protein functions, interactions, biological pathways, as well as human genetic diseases and variants, all manually reviewed by experts. In this article, we present an overview of the information content of UniProtKB/Swiss-Prot to show how this knowledgebase can support researchers in the elucidation of the mechanisms leading from a molecular defect to a disease phenotype.