997 resultados para ENDOPEPTIDASE 22.19
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Resumen tomado de la publicación
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Esta actividad, llevada a cabo con los niños de Infantil del pueblo de Coronil, se basa en la organización de una visita para que los niños conocieran las ruinas románicas de Itálica en Sevilla. Previamente a la visita, en el centro y con ayuda de los padres, se organiza un taller en el que los niños a través de juegos, la lectura de libros y gracias a sus propias creaciones aprenden un poco más de la vida de los romanos. Tras este taller, se realiza la visita a Itálica. Se conocen las ruinas de una forma un poco especial, ya que fue un animador caracterizado de Trajano el que les guia en la visita. La última parte del proyecto consiste en transformar el pueblo de Coronil en una villa romana. Se realiza una representación en la que se recrean los espacios y la forma de vida de los romanos. Los propios niños de infantil son los que realizan la representación.
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Incluye guiones, cuaderno del maestro, fotografías y algunos trabajos
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Monogr??fico con el t??tulo: Educaci??n Social en la escuela. Resumen tomado de la publicaci??n
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Perturbations to the carbon cycle could constitute large feedbacks on future changes in atmospheric CO2 concentration and climate. This paper demonstrates how carbon cycle feedback can be expressed in formally similar ways to climate feedback, and thus compares their magnitudes. The carbon cycle gives rise to two climate feedback terms: the concentration–carbon feedback, resulting from the uptake of carbon by land and ocean as a biogeochemical response to the atmospheric CO2 concentration, and the climate–carbon feedback, resulting from the effect of climate change on carbon fluxes. In the earth system models of the Coupled Climate–Carbon Cycle Model Intercomparison Project (C4MIP), climate–carbon feedback on warming is positive and of a similar size to the cloud feedback. The concentration–carbon feedback is negative; it has generally received less attention in the literature, but in magnitude it is 4 times larger than the climate–carbon feedback and more uncertain. The concentration–carbon feedback is the dominant uncertainty in the allowable CO2 emissions that are consistent with a given CO2 concentration scenario. In modeling the climate response to a scenario of CO2 emissions, the net carbon cycle feedback is of comparable size and uncertainty to the noncarbon–climate response. To quantify simulated carbon cycle feedbacks satisfactorily, a radiatively coupled experiment is needed, in addition to the fully coupled and biogeochemically coupled experiments, which are referred to as coupled and uncoupled in C4MIP. The concentration–carbon and climate–carbon feedbacks do not combine linearly, and the concentration–carbon feedback is dependent on scenario and time.
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This paper presents a new analysis of ocean heat content changes over the last 50 yr using isotherms by calculating the mean temperature above the 148C isotherm and the depth of the 148C isotherm as separate variables. A new quantity called the ‘‘relative heat content’’ (‘‘RHC’’) is introduced, which represents the minimum local heat content change over time, relative to a fixed isotherm. It is shown how mean temperature and isotherm depth changes make separable and additive contributions to changes in RHC. Maps of RHC change between 1970 and 2000 show similar spatial patterns to a traditional fixed-depth ocean heat content change to 220 m. However, the separate contributions to RHC suggest a more spatially uniform contribution from warming above the isotherm, while isotherm depth changes show wind-driven signals, of which some are identifiable as being related to the North Atlantic Oscillation. The time series show that the warming contribution to RHC dominates the global trend, while the depth contribution only dominates on the basin scale in the North Atlantic. The RHC shows minima associated with the major volcanic eruptions (particularly in the Indian Ocean), and these are entirely contributed by mean temperature changes rather than isotherm depth changes. The depth change contributions to RHC are strongly affected by the recently reported XBT fall-rate bias, whereas the mean temperature contributions are not. Therefore, only the isotherm depth change contributions toRHCwill need to be reassessed as fall-rate-corrected data become available.
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This review article addresses recent advances in the analysis of foods and food components by capillary electrophoresis (CE). CE has found application to a number of important areas of food analysis, including quantitative chemical analysis of food additives, biochemical analysis of protein composition, and others. The speed, resolution and simplicity of CE, combined with low operating costs, make the technique an attractive option for the development of improved methods of food analysis for the new millennium.
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Cells are able to detect and respond to mechanical cues from their environment. Previous studies have investigated this mechanosensitivity on various cell types, including neural cells such as astrocytes. In this study, we have carefully optimized polyacrylamide gels, commonly used as compliant growth substrates, considering their homogeneity in surface topography, mechanical properties, and coating density, and identified several potential pitfalls for the purpose of mechanosensitivity studies. The resulting astrocyte response to growth on substrates with shear storage moduli of G` = 100 Pa and G` = 10 kPa was then evaluated as a function of coating density of poly-D-lysine using quantitative morphometric analysis. Astrocytes cultured on stiff substrates showed significantly increased perimeter, area, diameter, elongation, number of extremities and overall complexity if compared to those cultured on compliant substrates. A statistically significant difference in the overall morphological score was confirmed with an artificial intelligence-based shape analysis. The dependence of the cells` morphology on PDL coating density seemed to be weak compared to the effect of the substrate stiffness and was slightly biphasic, with a maximum at 10-100 mu g ml(-1) PDL concentration. Our finding suggests that the compliance of the surrounding tissue in vivo may influence astrocyte morphology and behavior.
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In most cultures, dreams are believed to predict the future on occasion. Several neurophysiological studies indicate that the function of sleep and dreams is to consolidate and transform memories, in a cyclical process of creation, selection and generalization of conjectures about the reality. The aim of the research presented here was to investigate the possible adaptative role of anticipatory dreams. We sought to determine the relationship between dream and waking in a context in which the adaptive success of the individual was really at risk, in order to mobilize more strongly the oneiric activity. We used the entrance examination of the Federal University of Rio Grande do Norte (UFRN) as a significant waking event in which performance could be independently quantified. Through a partnership with UFRN, we contacted by e-mail 3000 candidates to the 2009 examination. In addition, 150 candidates were approached personally. Candidates who agreed to participate in the study (n = 94) completed questionnaires specific to the examination and were asked to describe their dreams during the examinaton period. The examination performance of each candidate in the entrance examination was provided by the UFRN to the researcher. A total of 45 participants reported dreams related to the examination. Our results show a positive correlation between performance on the examination and anticipatory dreams with the event, both in the comparison of performance on objective and discursive, and in final approval (in the group that not dreamed with the exam the rate of general approval, 22,45%, was similar to that found in the selection process as a whole, 22.19%, while for the group that dreamed with the examination that rate was 35.56%). The occurrence of anticipatory dreams reflectes increased concern during waking (psychobiological mobilization) related to the future event, as indicated by higher scores of fear and apprehension, and major changes in daily life, in patterns of mood and sleep, in the group that reported testrelated dreams. Furthermore, the data suggest a role of dreams in the determination of environmentally relevant behavior of the vigil, simulating possible scenarios of success (dream with approval) and failure (nightmares) to maximize the adaptive success of the individual
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The aim of this work was to study a series of 11 different compositions of Ti-Zr binary alloys resistance to aggressive environment, i. e., their ability to keep their surface properties and mass when exposed to them as a way to evaluate their performance as biomaterials. The first stage was devoted to the fabrication of tablets from these alloys by Plasma-Skull casting method using a Discovery Plasma machine from EDG Equipamentos, Brazil. In a second stage, the chemical composition of each produced tablet was verified. In a third stage, the specimen were submitted to: as-cast microstructure analysis via optical and scanning electron microscopy (OM and SEM), x-ray dispersive system (EDS) chemical analysis via SEM, Vickers hardness tests for mechanical evaluation and corrosion resistence tests in a 0.9% NaCl solution to simulate exposition to human saliva monitored by open circuit potential and polarization curves. From the obtained results, it was possible to infer that specimens A1 (94,07 wt% Ti and 5,93% wt% Zr), A4 (77,81 wt % Ti and 22,19 wt % Zr) and A8 (27,83 wt% Ti and 72,17 wt% Zr), presented best performance regarding to corrosion resistance, homogeneity and hardness which are necessary issues for biomaterials to be applied as orthopedic and odontological prosthesis
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Este trabalho traz elementos para avaliar a esperança de sustentabilidade de sistemas de produção rural presentes na Amazônia. Faz uma caracterização desses sistemas e seus fundamentos produtivos e reprodutivos na mesorregião Nordeste Paraense, a mais densamente povoada do Estado do Pará, e constrói indicadores que incorporam, além de variáveis econômicas, variáveis que enunciam esperança de maior eficiênciaecológica. Pretende contribuir com novas perspectivas para as discussões sobre desenvolvimento e oferecer instrumentos para orientar as instituições que decidem por critérios de sustentabilidade.