943 resultados para Drinking in the Bible.


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Trans. of Voyage autour de la mer Morte.

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Alcohol use disorders (AUDs) are a major public health problem, and the few treatment options available to those seeking treatment offer only modest success rates. There remains a need to identify novel targets for the treatment of AUDs. The neuronal nicotinic acetylcholine receptors (nAChRs) represent a potential therapeutic target in the brain, as recent human genetic studies have implicated gene variants in the α5 nAChR subunit as high risk factors for developing alcohol dependence. Here, we evaluate the role of 5* nAChR for ethanol-mediated behaviors using α5+/+ and α5-/- mice. We characterized the effect of hypnotic doses of ethanol and investigated drinking behavior using an adapted Drinking-in-the Dark (DID) paradigm that has been shown to induce high ethanol consumption in mice. We found the α5 subunit to be critical in mediating the sedative effects of ethanol. The α5-/- mice showed slower recovery from ethanol-induced sleep, as measured by loss of righting reflex. Additionally the α5-/- mice showed enhanced impairment to ethanol-induced ataxia. We found the initial sensitivity to ethanol and ethanol metabolism to be similar in both α5+/+ and α5-/- mice. Hence the enhanced sedation is likely due to a difference in the acute tolerance of ethanol in mice deficient of the α5 subunit. However the α5 subunit did not play a role in ethanol consumption for ethanol concentrations ranging from 5% to 30% in the DID paradigm. Additionally, varenicline (Chantix®) was effective in reducing ethanol intake in α5-/- mice. Together, our data suggest that the α5 nAChR subunit is important for the sedative hypnotic doses of ethanol but does not play a role in ethanol consumption. Varenicline can be a treatment option even when there is loss of function of the α5 nAChR subunit.

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The present study investigated the longitudinal relationship between alcohol consumption at age 13, and at age 16. Alcohol-specific measures were frequency of drinking, amount consumed at last use and alcohol related harms. Self-report data were gathered from 1113 high school students at T1, and 981 students at T2. Socio-demographic data were gathered, as was information on context of use, alcohol-related knowledge and attitudes, four domains of aggression and delay reward discounting. Results indicated that any consumption of alcohol, even supervised consumption, at T1 was associated with significantly poorer outcomes at T2. In other words, compared to those still abstinent at age 13, those engaging in alcohol use in any context reported significantly more frequent drinking, more alcohol-related harms and more units consumed at last use at age 16. Results also support the relationship between higher levels of physical aggression at T1 and a greater likelihood of more problematic alcohol use behaviours at T2. The findings support other evidence suggesting that abstinence in early adolescence has better longitudinal outcomes that supervised consumption of alcohol. These results suggest support for current guidance on adolescent drinking in the United Kingdom (UK).

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Biblical justifications for a vegetarian diet seem to meet with much adversity within mainstream American culture. Texts suggesting that people were intended to be vegetarians can be found in the Bible. However, this interpretation of Biblical texts has not been widely accepted by Protestant Christianity. This research attempts to identifY social and religious characteristics of people who are vegetarian. Fundamentalism, denomination, belief in the inerrancy of the Bible, and strength of belief in Christianity are examined as factors related to supporting vegetarianism. The General Social Survey's data from 1993 and 1994 were used in this study. The data were analyzed using frequencies, means, cross tabulations. correlations, and regressions. The sample was 57% female and 87% white, the mean age was 46 and the average level of education was 13 years. The study found that, among the independent variables. belief in animal rights, rather than any specific religious views, had the strongest influence on vegetarianism.

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"Entered, according to Act of Congress, in the year 1854, by Lindsay & Blakiston ... Stereotyped by J. Fagan, printed by C. Sherman, plates printed by T. Sinclair"--Verso of title page.

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"This book is composed of three lectures, on the L.P. Stone foundation, delivered at Princeton theological seminary, on the third, fourth, and fifth of February, 1919."

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The first edition of the German original was issued Frankfurt, 1700, under the title "Entdecktes judenthum", but was suppressed until after a second edition appeared at Königsberg, 1711. Editions of the translation, with preface by J.P. Stehelin, were issued 1732-34 and 1742 under title: The traditions of the Jews ...

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Lectures delivered during author's ministry each Sabbath, winter of 1847-48.

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Mode of access: Internet.