999 resultados para Burnet, Thomas, 1635?-1715.


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Signaturas: *6, A-F4, G2, H-Z4, 2A-2Z4, 3A-3Z4, 4A-4Z4, 5A-5D4, 5E2, 5F4 ; *5, A-Z4, 2A-2Z4, 3A-3Y4, Z2, 4A4 ; *5, A-Z4, 2A-2Z4, 3A-3Z4, 4A-4N4, 4O5 ; *5, A-Z4, 2A-2Z4, 3A-3Z4, 4A-4O4, 4P2, 4Q1, 4R4 ; *5, A-Z4, 2A-2Z4, 3A-3M4, *2, A-S4.

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Natural killer cells constitute a population of lymphocytes able to non-specifically destroy virus-infected and some kinds of tumor cells. Since this lytic activity was shown by non-immunized animals the phenomenon is denominated natural killer (NK) activity and contrasts with specific cytotoxicity performed by cytolytic T lymphocytes (CTLs) because it does not depends on MHC-restricted peptides recognition. In fact, the main feature of most functional receptors of NK cells (NKRs) is their ability to be inhibited by different kinds of class I MHC antigens. In the middle of the 1950's, Burnet & Thomas forged the concept of tumor immunosurveillance and NK cells can be considered one of the main figures in this phenomenon both for effector and regulatory functions. In the present review the early studies on the biology of NK cells were revisited and both their antitumor activity and dependence on the activation by cytokines are discussed.

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Sign.: []1, [parágrafo]4, A-Z4, 2A-2Z4, 3A-3X4, *-3*2, 4*1

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Mode of access: Internet.

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Mode of access: Internet.

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Mode of access: Internet.

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Mode of access: Internet.

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v. 1. The first part: Of the progress made in the reformation during the reign of King Henry VIII.--v. 2. The second part: Of the progress made in the reformation till the settlement of it in the beginning of Queen Elizabeth's reign.--v. 3. The third part: Being a supplement to the two formerly published.--v. 4-5. A collection of records, letters, and original papers, with other instruments referred to in the first [and second] part[s] ... [Appendices] concerning some of the errors and falsehoods in Sanders' book of the English schism.--v. 6. A collection of records ... [etc.] referred to in the third part ... --v. 7. Editors preface. Corrigenda et addenda. Chronological index of records. General index.

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v. 1, pt. 1 The history of the Reformation of the Church of England. Of the progress made in it during the reign of King Henry VIII.--v. 1,pt. 2. A collection of records and original papers, with other instruments referred to in the former history.--v. 2,pt. 1. Of the progress made in it till the settlement of it in the beginning of Queen Elizabeth's reign.--v. 2.,pt. 2. A collection of records and original papers; with other instruments referred to in the second part of the history of the Reformation of the Church of England.--v. 3,pt. 1. Being a supplement to the two former parts.--v. 3,pt. 2. A collection of records, letters, and original papers; with other instruments referred to in the former history.

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Mode of access: Internet.