Comparison of the antidiabetic activity of Berberis lyceum root extract and berberine in alloxan-induced diabetic rats

Berberine has been shown to have hypoglycaemic activity in several in vitro and in vivo models, although the mechanism of action is not fully known. Berberis lyceum Royle root produces high concentrations of berberine, and in traditional medicine, the whole extract of this plant is used widely to treat diabetes. The antidiabetic activity of the ethanol root extract of Berberis lyceum was compared with pure berberine in normal and alloxan-diabetic rats using similar doses of each. The concentration of berberine in the extract was determined to be 80% dry weight with only trace amounts of other alkaloids present. The purpose of the study was to investigate the effects of berberine and a whole extract of Berberis lyceum on blood glucose and other parameters associated with diabetes, to compare the effects of the crude extract with those of pure berberine and thus validate its use as a therapeutic agent, and finally to identify any contribution of the other components of the extract to these effects. Oral administration of 50 mg/kg of Berberis extract and berberine to normal and experimental diabetic rats produced a significant (p < 0.05) reduction in blood glucose levels from days 3-7 days of treatment. Significant effects were also observed on the glucose tolerance, glycosylated haemoglobin, serum lipid profiles and body weight of experimental animals. Berberis extract and berberine demonstrated similar effects on all parameters measured, and although the extract was comparable in efficacy to berberine, it did not produce any effects additional to those shown by pure berberine. The results support the use of the extract in traditional medicine, and demonstrate that apart from being a highly cost-effective means of treating with berberine, the total extract does not appear to confer any additional benefits or disadvantages compared with the pure compound. Copyright (c) 2008 John Wiley & Sons, Ltd.

Attityder till betygsättning i ordning och uppförande : En studie bland lärare och elever i Ålands lyceum

Syftet med den här uppsatsen har varit att ta reda på hur lärare och elever i Ålands lyceum förhåller sig till ordnings- och uppförandekriterier i betygsättningen. Vi har sett på skillnader mellan kön och också mellan olika ämnen och vi har också jämfört vårt resultat med tidigare undersökningar som gjorts i Sverige. Vår undersökning har gjorts bland 104 elever i årskurs två på gymnasiet och åtta lärare i ämnena matematik, historia, svenska och idrott. Undersökningen bland eleverna gjordes genom enkäter och bland lärarna genom intervjuer.Resultatet visar att lärarna tycker att ordning och uppförande ska vägas in i ämnesbetyget, precis som det görs nu i Ålands lyceum. Det har visat sig att en majoritet av eleverna vill ha ett separat betyg eller omdöme i ordning och uppförande. Flickorna är klart positivare till ett separat betyg i ordning och uppförande. De tycker också att ordnings- och uppförandekriterier ska vägas in mera i betygen. Det som vi också kommit fram till är att lärarna följer läroplanen i stor utsträckning, vilket till stor del beror på att de fått göra den själva. Resultaten mellan vår undersökning och tidigare undersökningar gjorda i Sverige skiljer sig inte så mycket, trots att lärarna på Åland ska ta hänsyn till ordning och uppförande i betygsättningen, medan lärarna i Sverige inte ska det.

The Proscenium of the English Opera House in the Strand, (Late Lyceum), as it appeared on the Evening of the 21st. March 1817, with Walker's Exhibition of the Eidouranian - Front Boxes and Gallery

Signatur des Originals: S 36/G03857

New York, N.Y. and vicinity, 1961 : Brooklyn, N.Y.-N.J. (8 Sheet Set) (Raster Image)

This layer is a georeferenced raster image of the United States Geological Survey 7.5 minute topographic sheet map entitled: New York and vicinity : Brooklyn, N.Y.-N.J., 1957. It is part of an 8 sheet map set covering the metropolitan New York City area. It was published in 1961. Scale 1:24,000. The source map was prepared by the Geological Survey from 1:24,000-scale maps of Jamaica 1957, Brooklyn 1956, Coney Island 1955, and Far Rockaway 1954 7.5 minute quadrangles. The Far Rockaway quadrangle was previously compiled by the Army Map Service. Culture revised by the Geological Survey. Hydrography compiled from USC&GS charts 542 (1955), 745 (1956), and 369 (1956). The image inside the map neatline is georeferenced to the surface of the earth and fit to the Universal Transverse Mercator (UTM) Zone 18N NAD27 projection. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. USGS maps are typical topographic maps portraying both natural and manmade features. They show and name works of nature, such as mountains, valleys, lakes, rivers, vegetation, etc. They also identify the principal works of humans, such as roads, railroads, boundaries, transmission lines, major buildings, etc. Relief is shown with standard contour intervals of 10 and 20 feet; depths are shown with contours and soundings. Please pay close attention to map collar information on projections, spheroid, sources, dates, and keys to grid numbering and other numbers which appear inside the neatline. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

Agreement between the city of New York through the Board of Estimate and Apportionment and the Brooklyn Public Library.

Mode of access: Internet.

The Brooklyn Museum quarterly /

Title from cover.

The Collector's eye : the Ernest Erickson collections at the Brooklyn Museum /

Catalog of an exhibition held at the Brooklyn Museum, Mar. 27-May 18, 1987.

Fugitive slave law [electronic resource] : The religious duty of obedience to law; a sermon preached in the Second Presbyterian Church in Brooklyn, Nov. 24, 1850. /

Electronic text and image data.

Contributions - Brooklyn Botanic Garden.

This series consists of papers originally published in botanical or other periodicals, re-issued as "separates" without change of paging, and numbered consecutively.

Bulletin of the Brooklyn Entomological Society.

Mode of access: Internet.

Philippines freedom two generations hence : [address before audience in Academy of music, Brooklyn, November 19, 1913].

Clipping from Brooklyn daily eagle.

The ethics of the Greek philosophers, Socrates, Plato and Aristotle. A lecture given before the Brooklyn ethical association, season of 1896 1897,

Several of the plates are preceded by a leaf with descriptive letterpress.