Marques de biblioteca: Robert Brian Tate

Explicació del motius que Robert Brian Tate podia tenir per a triar l’humanista quatrecentista Joan Margarit i Pau com a figura del seu ex-libris

egr-4, a target of EGFR signaling, is required for the formation of the brian primordial and head regeneration in planarians

During the regeneration of freshwater planarians, polarity and patterning programs play essential roles in determining whether a head or a tail regenerates at anterior or posterior-facing wounds. This decision is made very soon after amputation. The pivotal role of the Wnt/β-catenin and Hh signaling pathways in re-establishing anterior-posterior (AP) polarity has been well documented. However, the mechanisms that control the growth and differentiation of the blastema in accordance with its AP identity are less well understood. Previous studies have described a role of Smed-egfr-3, a planarian epidermal growth factor receptor, in blastema growth and differentiation. Here, we identify Smed-egr-4, a zinc-finger transcription factor belonging to the early growth response gene family, as a putative downstream target of Smed-egfr-3. Smed-egr-4 is mainly expressed in the central nervous system and its silencing inhibits anterior regeneration without affecting the regeneration of posterior regions. Single and combinatorial RNA interference to target different elements of the Wnt/β-catenin pathway, together with expression analysis of brain- and anterior-specific markers, revealed that Smed-egr-4: (1) is expressed in two phases - an early Smed-egfr-3-independent phase and a late Smed-egfr-3-dependent phase; (2) is necessary for the differentiation of the brain primordia in the early stages of regeneration; and (3) that it appears to antagonize the activity of the Wnt/β-catenin pathway to allow head regeneration. These results suggest that a conserved EGFR/egr pathway plays an important role in cell differentiation during planarian regeneration and indicate an association between early brain differentiation and the proper progression of head regeneration.

Families of the traumatically brian-injured : a case study approach to perceptions of quality of service, degree of satisfaction, and family needs /

The purpose of this qualitative research study was to foster an understanding of the rehabilitation counselling practice offamilies of the brain-injured. Specifically, the study explores the perceptions of stakeholders in regards to the degree of satisfaction with the quality of service received. Questionnaires were administered, and semi-structured, openended interviews were conducted, with six participating families (n=8). Preliminary data were collected via two instruments: (i) the Family Participant Questionnaire, consisting of participants' sample characteristics, information pertaining to the history of the family, details of the injury, and information relating to the type, use, and need offamily services utilized; and (ii) the Community Integration Questionnaire, a measurement of the degree of social displacementllevel of community integration of the injured family member. Utilizing the procedural steps outlined by Colaizzi's (1978) method of protocol analysis, recommendations for a future program based on related and current family needs are discussed in detail. Substantiating and supporting information are offered to rehabilitation practitioners, educational planners, and policymakers alike, concerning the degree of satisfaction with rehabilitative service, and the means of improving upon the overall quality of health care to families of the brain-injured. Implications for clinical practice and research are also raised for discussion.

Menu - Dinner given by the Prime Minister of Canada The Right Honourable Brian Mulroney

A menu from a dinner given by The Right Honourable Brian Mulroney and Mrs. Mila Mulroney during a visit by the Prime Minister of the Italian Republic, Giulio Andreotti. The dinner was held March 8, 1992 at The Westin Harbour Castle in Toronto and features Inniskillin wines.

Aplicación de la metodología de Brian Blum al desarrollo del proyecto de David y Goliat

Tesis (Maestría en Informática) U.A.N.L.

Discurs del Dr. Robert Brian Tate com a doctor honoris causa per la Universitat de Girona

Discurs pronunciat pel Dr. Robert Brian Tate (Belfast, 1921), en el decurs de l'acte d'investidura de Doctors Honoris Causa, celebrat a la Universitat de Girona l'octubre de 2004. El seu discurs versa sobre la seva trajectòria professional

Discurs de presentació del professor Robert Brian Tate, a càrrec de la Dra. Mariàngela Vilallonga

En el discurs de concessió del doctorat honoris causa de la Universitat de Girona, la Dra. Mª Vilallonga glossa la lliçó d'història raonada i el llegat de Robert Brian Tate

Discurs del rector de la Universitat de Girona, Dr.Joan Batlle, en l'acte d'investidura com doctors honoris causa de Robert Brian Tate, Joan Bertran Rusca i Jaume Gil Aluja

Discurs d'investidura de doctors honoris causa per la Universitat de Girona, del rector Joan Batlle

Marques de biblioteca: Robert Brian Tate

Explicació del motius que Robert Brian Tate podia tenir per a triar l’humanista quatrecentista Joan Margarit i Pau com a figura del seu ex-libris