Recueil de nouvelles pieces philosophiques,

Edited by graf Ernst Christoph von Manteuffel.

Beschreibung des Königreichs Siam ...

A translation of the author's Du royaume de Siam, Paris, 1691.

Historia Iulii Caesaris.

This book, formerly ascribed to "Julius Celsus", was claimed for Petrarch, by Karl Ernst Christoph Schneider. cf. History of classical scholarship, by Sandys. v. 3, p. 115.

Albrecht Dürer.

Mode of access: Internet.

Christoph Ernst Friedrich Weyse, Brustbild

Signatur des Originals: S 36/G02507

Christoph Ernst Friedrich Weyse, Brustbild

Signatur des Originals: S 36/G04448

Christoph Daniel Ebelings, Professors der Geschichte am Hamburgischen Gymnasium und Bibliothekars, Erdbeschreibung und Geschichte von Amerika : die Vereinten Staaten von Nordamerika.

Vol. 7 has imprint: Hamburg 1816, bei Hoffmann und Campe.

Briefwechsel des Herzogs Christoph von Wirtemberg /

Includes bibliographies.

Ad virum nobilissimum atque excellentissimum dominum doctorem Albertum Hallerum medicum et anatomicum apud bernenses helvetos clarissimum De vasis linguae salivalibus atque sanguiferis epistola Christoph. Iacobi Trevv, med. doct. reip. Norimb. ...

Mode of access: Internet.

Review of "Christoph Schlingensief : art without borders" edited by Tara Forrest and Anna Teresa Scheer

Christoph Schlingensief: Art Without Borders, edited by Tara Forrest and Anna Teresa Scheer, is the first English-language collection of essays about this extraordinary German artist. As Forrest and Scheer suggest in their introduction, ‘access to Schlingensief’s highly challenging productions has been hampered by the fact that very little has been published on his oeuvre in the English-speaking world’. This collection aims to introduce English-speaking artists, scholars and academics to Schlingensief’s extensive, experimental, and at times highly controversial body of work across film, theatre, television, live art and activism...

Prevalence and clinical outcomes for patients with ALK-positive resected stage I to III adenocarcinoma : results from the European Thoracic Oncology Platform Lungscape Project

PURPOSE: The prevalence of anaplastic lymphoma kinase (ALK) gene fusion (ALK positivity) in early-stage non-small-cell lung cancer (NSCLC) varies by population examined and detection method used. The Lungscape ALK project was designed to address the prevalence and prognostic impact of ALK positivity in resected lung adenocarcinoma in a primarily European population. METHODS: Analysis of ALK status was performed by immunohistochemistry (IHC) and fluorescent in situ hybridization (FISH) in tissue sections of 1,281 patients with adenocarcinoma in the European Thoracic Oncology Platform Lungscape iBiobank. Positive patients were matched with negative patients in a 1:2 ratio, both for IHC and for FISH testing. Testing was performed in 16 participating centers, using the same protocol after passing external quality assessment. RESULTS: Positive ALK IHC staining was present in 80 patients (prevalence of 6.2%; 95% CI, 4.9% to 7.6%). Of these, 28 patients were ALK FISH positive, corresponding to a lower bound for the prevalence of FISH positivity of 2.2%. FISH specificity was 100%, and FISH sensitivity was 35.0% (95% CI, 24.7% to 46.5%), with a sensitivity value of 81.3% (95% CI, 63.6% to 92.8%) for IHC 2+/3+ patients. The hazard of death for FISH-positive patients was lower than for IHC-negative patients (P = .022). Multivariable models, adjusted for patient, tumor, and treatment characteristics, and matched cohort analysis confirmed that ALK FISH positivity is a predictor for better overall survival (OS). CONCLUSION: In this large cohort of surgically resected lung adenocarcinomas, the prevalence of ALK positivity was 6.2% using IHC and at least 2.2% using FISH. A screening strategy based on IHC or H-score could be envisaged. ALK positivity (by either IHC or FISH) was related to better OS.

Walter and Freddy Godshaw (Gottschalk) with their uncle Ernst Meyerhof; London, England.

From left to right: Walter Godshaw, Ernst Meyerhof, and Freddy Godshaw

Ernst Gottschalk sitting in a car petting his dog Whip; London, England.

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Portrait of Franz Catzenstein with his uncle Ernst Gottschalk.

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