HPV: lesões orais e periorais de comportamento benigno

Communication presented at the HPV 2015, 30th International Papillomavirus Conference, 17-21 September, Lisbon, Portugal.

[Los concilios nacionales de Toledo fueron asambleas eclesiásticas y nunca tuvieron el carácter de Cortes ó Estados generales del Reino] : discurso leído por Don Benigno Jimenez y Cubas, Licenciado en Jurisprudencia, en el acto solemne de recibir la investidura de Doctor en dicha Facultad.

Índice.

Osservazioni teologiche e critiche di monsignor Jacopo-Benigno Bossuet ... sopra gli errori contenuti nella nuova Biblioteca degli autori ecclesiastici del signor Dupin ... Si aggiungono la censura di monsign. Harlay arcivescovo di Parigi sopra la detta Biblioteca, e la ritrattazione dello stesso sign. Dupin. Traduzione dalla lingua franzese nella italiana.

Mode of access: Internet.

Diseño de un modelo de situación problema, con la unidad facilitadora solidaria llamada Belisol, para fortalecer el pensamiento numérico y variacional, en los estudiantes de la Institución Educativa Rural Benigno Mena González

Al analizar los resultados deficientes de las Pruebas Saber, del PTA ( Programa Todos a Aprender del MEN), y la participación en las Olimpiadas del Conocimiento, de los estudiantes de la Institución Educativa Rural Benigno Mena González del municipio de San Jerónimo, se consideró implementar un proyecto pedagógico, como plan de mejoramiento para la enseñanza y aprendizaje de las matemáticas, que sirviera como una iniciativa para fortalecer los pensamientos numérico y variacional en los estudiantes de secundaria de la Institución; se buscaba, con la implementación de esta propuesta, desarrollar habilidades en dominio, comprensión y solución de situaciones problemas cotidianas dentro del contexto escolar y desde la innovación de nuevas prácticas metodológicas en los procesos educativos. Desde esta perspectiva, nace el interrogante: ¿Cómo modelar una situación problema, teniendo como motivo la unidad facilitadora solidaria denominada Belisol, para fortalecer el pensamiento numérico y variacional, en los estudiantes de la Institución Educativa Rural Benigno Mena González del municipio de San Jerónimo?, para dar tránsito a una propuesta de investigación innovadora. Ahora bien, para intervenir y reflexionar sobre este interrogante, se propuso el método de Investigación Acción Participación (IAP), el cual se aplica a estudios que se interesan sobre realidades humanas y problemáticas cotidianas o sociales, que además, sean reales, de la acción, y de constante participación de los sujetos, entidades o comunidades involucradas; aquí cabe la posibilidad de un aprendizaje cooperativo, colectivo, y por supuesto, colaborativo donde se ha planteado como motivo de la situación problema planteada la unidad financiera llamada Belisol con el fin de exteriorizar los fundamentos de una acción formativa, orientada a la incursión en el ámbito de la educación matemática económica financiera, a través del ejercicio del ahorro escolar y el trueque, promoviendo de esta manera el espíritu solidario en la comunidad Benigniana.

Lipoidoproteinose

OBJETIVO: Apresentar as características clínicas, tratamento cirúrgico e achado histológico de um caso de lipoidoproteinose. DESCRIÇÃO DO CASO: Criança do sexo masculino, cinco anos de idade, branco, que procurou atendimento odontológico na Universidade. A mãe da criança relatou presença de intensa halitose e dificuldade na alimentação e higienização bucal, decorrentes de crescimento gengival generalizado nos arcos dentários superior e inferior. No exame clínico, verificaram-se comprometimento funcional e estético generalizado (rouquidão, artralgia bilateral no joelho e tornozelo, lesões tumorais nas orelhas, entre outros), além de extensa hiperplasia gengival em ambos os arcos dentários. Optou-se pelo tratamento cirúrgico, com remoção do tecido hiperplásico e exodontia de todos os dentes decíduos e de dois permanentes. O exame histopatológico da peça cirúrgica confirmou o diagnóstico de lipoidoproteinose. COMENTÁRIOS: A lipoidoproteinose é uma doença rara caracterizada pela deposição da substância hialina na pele, membranas mucosas e nos órgãos internos. Os sinais que podem surgir após o nascimento, são: rouquidão; lesões pápulo-nodulares na cabeça, pescoço e membros; lesões papulares amareladas nas margens das pálpebras. O curso desta doença é benigno e crônico.

Computed tomography and scintigraphy exams for diagnosis and treatment planning of the condylar osteochondroma: a case report

PURPOSE: To report an uncommon case of osteochondroma affecting the mandibular condyle of a young patient and to illustrate the important contributions of different imaging resources to the diagnosis and treatment planning of this lesion. CASE DESCRIPTION: A 24-year-old female patient with the chief complaint of an increasing facial asymmetry and pain in the left pre-auricular region, revealing a reduced mouth opening, mandibular deviation and posterior cross-bite over a period of 18 months. Panoramic radiography revealed an enlargement of the left condyle, whereas computed tomography (CT) sections and three-dimensional CT showed a well-defined bone growth arising from condylar neck. The scintigraphy exam showed an abnormal osteogenic activity in the left temporomandibular joint. The condyle was surgically removed and after 18 months follow-up the panoramic radiography and CT scans showed no signs of recurrence. CONCLUSION: Although osteochondroma is a benign bone tumor that rarely arises in cranial and maxillofacial region, it should be considered in the differential diagnosis of slow-growing masses of the temporomandibular area and the use of different imaging exams significantly contribute to the correct diagnosis and treatment planning of this pathological condition.

Neuromodulation approaches for the treatment of major depression: challenges and recommendations from a working group meeting

The use of neuromodulation as a treatment for major depressive disorder (MDD) has recently attracted renewed interest due to development of other non-pharmacological therapies besides electroconvulsive therapy (ECT) such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), deep brain stimulation (DBS), and vagus nerve stimulation (VNS). METHOD: We convened a working group of researchers to discuss the updates and key challenges of neuromodulation use for the treatment of MDD. RESULTS: The state-of-art of neuromodulation techniques was reviewed and discussed in four sections: [1] epidemiology and pathophysiology of MDD; [2] a comprehensive overview of the neuromodulation techniques; [3] using neuromodulation techniques in MDD associated with non-psychiatric conditions; [4] the main challenges of neuromodulation research and alternatives to overcome them. DISCUSSION: ECT is the first-line treatment for severe depression. TMS and tDCS are strategies with a relative benign profile of side effects; however, while TMS effects are comparable to antidepressant drugs for treating MDD; further research is needed to establish the role of tDCS. DBS and VNS are invasive strategies with a possible role in treatment-resistant depression. In summary, MDD is a chronic and incapacitating condition with a high prevalence; therefore clinicians should consider all the treatment options including invasive and non-invasive neuromodulation approaches.

Dengue and dengue hemorrhagic fever among adults: Clinical outcomes related to viremia, serotypes, and antibody response

Background. Clinical manifestations of dengue vary in different areas of endemicity and between specific age groups, whereas predictors of outcome have remained controversial. In Brazil, the disease burden predominantly affects adults, with an increasing trend toward progression to dengue hemorrhagic fever (DHF) noted. Methods. A cohort of adults with confirmed cases of dengue was recruited in central Brazil in 2005. Patients were classified according to the severity of their disease. Associations of antibody responses, viremia levels (as determined by real-time polymerase chain reaction [PCR]), and serotypes (as determined by multiplex PCR) with disease severity were evaluated. Results. Of the 185 symptomatic patients > 14 years of age who had a confirmed case of dengue, 26.5% and 23.2% were classified as having intermediate dengue fever (DF)/ DHF (defined as internal hemorrhage, plasma leakage, manifested signs of shock, and/ or thrombocytopenia [platelet count, <= 50,000 platelets/mm(3)]) and DHF, respectively. The onset of intermediate DF/ DHF and DHF occurred at a late stage of disease, around the period of defervescence. Patients with DHF had abnormal liver enzyme levels, with a > 3-fold increase in aspartate aminotransferase level, compared with the range of values considered to be normal. Overall, 65% of patients presented with secondary infections with dengue virus, with such infection occurring in similar proportions of patients in each of the 3 disease category groups. Dengue virus serotype 3 (DV3) was the predominant serotype, and viremia was detected during and after defervescence among patients with DHF or intermediate DF/ DHF. Conclusions. Viremia was detected after defervescence in adult patients classified as having DHF or intermediate DF/ DHF. Secondary infection was not a predictor of severe clinical manifestation in adults with infected with the DV3 serotype.