Effects of pH on asexual reproduction and statolith formation of the scyphozoan, Aurelia labiata, 2010

Although anthropogenic infuences such as global warming, overfishing, and eutrophication may contribute to jellyfish blooms, little is known about the effects of ocean acidification on jellyfish. Most medusae form statoliths of calcium sulfate hemihydrate that are components of their balance organs (statocysts). This study was designed to test the effects of pH (7.9, within the average current range, 7.5, expected by 2100, and 7.2, expected by 2300) combined with two temperatures (9 and 15°C) on asexual reproduction and statolith formation of the moon jellyfish, Aurelia labiata. Polyp survival was 100% after 122 d in seawater in all six temperature and pH combinations. Because few polyps at 9°C strobilated, and temperature effects on budding were consistent with published results, we did not analyze data from those three treatments further. At 15°C, there were no significant effects of pH on the numbers of ephyrae or buds produced per polyp or on the numbers of statoliths per statocyst; however, statolith size was signi?cantly smaller in ephyrae released from polyps reared at low pH. Our results indicate that A. labiata polyps are quite tolerant of low pH, surviving and reproducing asexually even at the lowest tested pH; however, the effects of small statoliths on ephyra fitness are unknown. Future research on the behavior of ephyrae with small statoliths would further our understanding of how ocean acidi?cation may affect jellyfish survival in nature.

El 24 de junio de 1935 : Suncha, Estrellita y Aurelia derramaron lágrimas por Carlitos

Fondo Margaritainés Restrepo

Risk Profiles and Penetrance Estimations in Multiple Endocrine Neoplasia Type 2A Caused by Germline RET Mutations Located in Exon 10

Multiple endocrine neoplasia type 2 is characterized by germline mutations in RET. For exon 10, comprehensive molecular and corresponding phenotypic data are scarce. The International RET Exon 10 Consortium, comprising 27 centers from 15 countries, analyzed patients with RET exon 10 mutations for clinical-risk profiles. Presentation, age-dependent penetrance, and stage at presentation of medullary thyroid carcinoma (MTC), pheochromocytoma, and hyperparathyroidism were studied. A total of 340 subjects from 103 families, age 4-86, were registered. There were 21 distinct single nucleotide germline mutations located in codons 609 (45 subjects), 611 (50), 618 (94), and 620 (151). MTC was present in 263 registrants, pheochromocytoma in 54, and hyperparathyroidism in 8 subjects. Of the patients with MTC, 53% were detected when asymptomatic, and among those with pheochromocytoma, 54%. Penetrance for MTC was 4% by age 10, 25% by 25, and 80% by 50. Codon-associated penetrance by age 50 ranged from 60% (codon 611) to 86% (620). More advanced stage and increasing risk of metastases correlated with mutation in codon position (609-620) near the juxtamembrane domain. Our data provide rigorous bases for timing of premorbid diagnosis and personalized treatment/prophylactic procedure decisions depending on specific RET exon 10 codons affected. Hum Mutat 32:51-58, 2011. (C) 2010 Wiley-Liss, Inc.

Foucault and Feminism

Online encyclopedia providing detailed, scholarly information on key topics and philosophers in all areas of philosophy. The IEP is free of charge, is available to all internet users world wide, and is continually revised and updated.

Fungos contaminantes e produtores de aflatoxinas em castanha do Pará (Bertholletia excelsa HUMB. & BONPL 1808)

Cem amostras de castanhas do Para, procedentes dos Estados do Amazonas e Sao Paulo, foram analisadas micológico e toxicologicamente para aflatoxinas B1 e G1. Isolou-se 312 colônias de fungos, sendo 91 do gênero Aspergillus, 83 do gênero Penicillium e as restantes incluídas em 23 gêneros diferentes. Entre as amostras de Aspergillus, 26 foram aflatoxigênicos, distribuídos em 3 espécies: Aspergillus flavas Link (18); Aspergillus parasiticus Speare (7) e Aspergillus fresenii Subram (1). Dos 100 extratos de castanhas analisados 3 foram positivos para aflatoxina.

Cubozoa e Scyphozoa (Cnidaria: Medusozoa) de águas costeiras do Brasil

As espécies de Cubozoa e Scyphozoa costeiras que ocorrem no Brasil são descritas, com base em espécimes de coleções de museus e exemplares recém-coletados. Chaves de identificação e um glossário também são apresentados. As espécies descritas são: Aurelia sp.; Cassiopea xamachana Bigelow, 1892; Chiropsalmus quadrumanus (Müller, 1859); Chrysaora lactea Eschscholtz, 1829; Drymonema dalmatinum Haeckel, 1880; Linuche unguiculata (Swartz, 1788); Lychnorhiza lucerna Haeckel, 1880; Nausithoe aurea Silveira & Morandini, 1997; Phyllorhiza punctata von Lendenfeld, 1884; Stomolophus meleagris Agassiz, 1862; Tamoya haplonema Müller, 1859 e Tripedalia cystophora Conant, 1897.

Regulatory assessment of in vitro skin corrosion and irritation data within the European framework: Workshop recommendations

Validated in vitro methods for skin corrosion and irritation were adopted by the OECD and by the European Union during the last decade. In the EU, Switzerland and countries adopting the EU legislation, these assays may allow the full replacement of animal testing for identifying and classifying compounds as skin corrosives, skin irritants, and non irritants. In order to develop harmonised recommendations on the use of in vitro data for regulatory assessment purposes within the European framework, a workshop was organized by the Swiss Federal Office of Public Health together with ECVAM and the BfR. It comprised stakeholders from various European countries involved in the process from in vitro testing to the regulatory assessment of in vitro data. Discussions addressed the following questions: (1) the information requirements considered useful for regulatory assessment; (2) the applicability of in vitro skin corrosion data to assign the corrosive subcategories as implemented by the EU Classification, Labelling and Packaging Regulation; (3) the applicability of testing strategies for determining skin corrosion and irritation hazards; and (4) the applicability of the adopted in vitro assays to test mixtures, preparations and dilutions. Overall, a number of agreements and recommendations were achieved in order to clarify and facilitate the assessment and use of in vitro data from regulatory accepted methods, and ultimately help regulators and scientists facing with the new in vitro approaches to evaluate skin irritation and corrosion hazards and risks without animal data.

Introducció: Violencia deliberada. Las raíces de la violencia patriarcal

El dominio de los hombres sobre las mujeres es un fenómeno histórico que caracteriza las formaciones sociales estatales de Grecia y Roma, del Próximo Oriente antiguo y del Egipto faraónico, y son los distintos tipos de violencia —física, sexual y simbólica— sus herramientas principales de construcción y de permanencia.Este libro reúne las ponencias presentadas en el simposio internacional Violencia deliberada. Sus autoras y autores analizan las violencias sexistas que, desde la antigüedad, como si se tratara de un hecho ineluctable, impregnan las vidas de muchas mujeres, como Neera, la extranjera; Pacula Annia, la sacerdotista, y Agripina, la madre de Nerón, o Aurelia Atiena, la ninfa Io y la virgen asceta Principia. Ellas y otras muchas, cuyos nombres desconocemos, son las verdaderas protagonistas de este libro. Del valor y la determinación de las mujeres nombradas y evocadas en estas páginas, y de tantas otras con las que compartimos hoy nuestras vidas, surgen la luz y el aliento para (re)accionar frente a las violencias patriarcales.

Introducció: Violencia deliberada. Las raíces de la violencia patriarcal

El dominio de los hombres sobre las mujeres es un fenómeno histórico que caracteriza las formaciones sociales estatales de Grecia y Roma, del Próximo Oriente antiguo y del Egipto faraónico, y son los distintos tipos de violencia —física, sexual y simbólica— sus herramientas principales de construcción y de permanencia.Este libro reúne las ponencias presentadas en el simposio internacional Violencia deliberada. Sus autoras y autores analizan las violencias sexistas que, desde la antigüedad, como si se tratara de un hecho ineluctable, impregnan las vidas de muchas mujeres, como Neera, la extranjera; Pacula Annia, la sacerdotista, y Agripina, la madre de Nerón, o Aurelia Atiena, la ninfa Io y la virgen asceta Principia. Ellas y otras muchas, cuyos nombres desconocemos, son las verdaderas protagonistas de este libro. Del valor y la determinación de las mujeres nombradas y evocadas en estas páginas, y de tantas otras con las que compartimos hoy nuestras vidas, surgen la luz y el aliento para (re)accionar frente a las violencias patriarcales.

The burnout syndrome and associated personality disturbances. The study in three graduate programs in Dentistry at the University of Barcelona

Objective: Determine the presence of"burnout" syndrome and characteristic personality patterns in the students and faculty of three graduate programs in Dentistry at the University of Barcelona: Department of Oral Surgery and Implantology, Department of Orthodontics and Department of Integrated Dentistry. Materials and Methods: The study was carried out in 78 dentists. The level of"burnout" was evaluated using the Maslach Burnout Inventory, socio-demographic variables and, finally, the personality test. Results: Oral surgeons constituted the group of highlevel"burnout". The profile of an individual with a propensity to"burn out" is a single man, with a median age of 27, that is in the first years of the graduate program and that combines studies with 30 hours of clinical practice and/or other work (p<0,05). Narcissistic and borderline are the types of personality most frequently found in the individuals that present"burnout" syndrome (p<0,05). Conclusions: In general, no high levels of"burnout" were registered in the studied population, only 2-3%, if applying strict definition of"burnout", and 10% if these criteria were amplified. We believe it is necessary to identify the individuals with a tendency towards"burnout", in order to establish preventive measures and avoid future negative behaviour at work as well as at the personal level.

Assessing positive mental health in people with chronic physical health problems: correlations with socio-demographic variables and physical health status

Background: A holistic perspective on health implies giving careful consideration to the relationship between physical and mental health. In this regard the present study sought to determine the level of Positive Mental Health (PMH) among people with chronic physical health problems, and to examine the relationship between the observed levels of PMH and both physical health status and socio-demographic variables. Methods: The study was based on the Multifactor Model of Positive Mental Health (Lluch, 1999), which comprises six factors: Personal Satisfaction (F1), Prosocial Attitude (F2), Self-control (F3), Autonomy (F4), Problem-solving and Self-actualization (F5), and Interpersonal Relationship Skills (F6). The sample comprised 259 adults with chronic physical health problems who were recruited through a primary care center in the province of Barcelona (Spain). Positive mental health was assessed by means of the Positive Mental Health Questionnaire (Lluch, 1999). Results: Levels of PMH differed, either on the global scale or on specific factors, in relation to the following variables: age: global PMH scores decreased with age (r=-0.129; p=0.038); b) gender: men scored higher on F1 (t=2.203; p=0.028) and F4 (t=3.182; p=0.002), while women scored higher on F2 (t -3.086; p=0.002) and F6 (t=-2.744; p=0.007); c) number of health conditions: the fewer the number of health problems the higher the PMH score on F5 (r=-0.146; p=0.019); d) daily medication: polymedication patients had lower PMH scores, both globally and on various factors; e) use of analgesics: occasional use of painkillers was associated with higher PMH scores on F1 (t=-2.811; p=0.006). There were no significant differences in global PMH scores according to the type of chronic health condition. The only significant difference in the analysis by factors was that patients with hypertension obtained lower PMH scores on the factor Autonomy (t=2.165; p=0.032). Conclusions: Most people with chronic physical health problems have medium or high levels of PMH. The variables that adversely affect PMH are old age, polypharmacy and frequent consumption of analgesics. The type of health problem does not influence the levels of PMH. Much more extensive studies with samples without chronic pathology are now required in order to be able to draw more robust conclusions.

Recueil de pièces fugitives sur divers personnages du temps de Charles IX, et analyse de divers ouvrages du xviie siècle.

Contient : « Passio domini nostri cardinalis Saccheti » ; Paralèlle de M. le Prince [de Condé] et de M. de Turene, » in-impr ; « Epistre du coq à l'asne (1565 et 1585) » ; « L'arche de Noë (1585) » ; « De Gasparo Colignio » ; « La Nicque à Nocque (1585) » ; « Le désespoir du Courtisan » ; « Coq à l'asne (1585) » ; « Le songe de Chicot » ; « Li popoli a l'archiduca » ; « Le qu'as-tu veu de la Cour » ; « Novelle de Aurelia (1561) ; » publiée par MM. Baguenault de Puchesse, Auvray et de Lacombe, Documents sur les guerres de religion dans l'Orléanais. (Orléans, 1902, in-8°), p. 13 ; « Complainte de M. Pierre Lizet sur le trespas de son nez » ; « Epitaphe du mullet de Berthelin, lieutenant de Nyort (1559) » ; « La ville de Paris au cardinal de Lorraine » ; « Imitation des maudissons d'Ovide contre Ibis » ; « Sur Pierre Ronsard » ; Sonnets, épitaphes et autres pièces sur les principaux personnages du temps de Charles IX, François de Lorraine, duc de Guise (fol. 129), Charles, cardinal de Lorraine (fol. 130), Catherine de Médicis (fol. 133), Antoine de Bourbon, roi de Navarre (fol. 136), D'Escars (fol. 138), Ruzé général des finances (fol. 140), Marie Stuart (fol. 142), Dolet (fol. 143), Paul III et Paul IV (fol. 144), le président Lizet (fol. 144), Jules III et les cardinaux, (fol. 145), Louis Guillard, évêque de Chartres (fol. 146), le président Gentil, Marot (fol. 150), Cl. Le Sueur (fol. 151), Jacques de Beaune [Samblançay] (fol. 152), le maréchal de Brissac (fol. 156), Jean Péricard (fol. 157), Jeanne d'Albret (fol. 166), divers procureurs, gens des comptes, etc ; Analyses et extraits de divers ouvrages des PP. Senault et Le Moyne, de Balzac, de Scudéry, Gombaud, Malleville, président Maynard, Voiture, Perrot d'Ablancourt, Pietro della Valle, Molière, Tristan l'Hermite, l'abbé de Marolles, la légation du cardinal Chigi (1664), Brantôme, L'Estoile, baron de l'Isola, Condé, Bussy-Rabutin, Pasquin, etc