Cruise Report 71-S-3

(PDF contains 7 pages.)

Cruise Report 71-S-5: Bottomfish

(PDF contains 8 pages.)

Cruise Report 71-S-6: Sportfish Investigations

(PDF contains 1 pages.)

Cruise Report 71-S-7: Crab

(PDF contains 6 pages.)

Cruise Report 71-S-8: Crab

(PDF contains 3 pages.)

Diário da Constituinte [gravação de vídeo] : [programa n. 387]

Já estão prontas as emendas que a liderança do PMDB vai apresentar ao projeto de Constituição. São ao todo 50 emendas sobre os seguintes pontos: mandato - o partido defende 4 anos para o Presidente Sarney, Sistema de Governo - Parlamentarismo, Estabilidade - garantia de emprego contra as demissões imotivadas, saúde - defende o sistema único, meio ambiente - mantém o texto da Sistematização que protege o meio ambiente, Empresa Nacional - empresa com sede no Brasil e com controle de pessoas que residam no país, Questão Indígena - quer ampliar o texto do projeto para garantir aos índios a posse e a demarcação das suas terras, Estabilidade do Servidor Público- não concorda com o artigo que dá estabilidade a todos os servidores com mais de 5 anos de serviço. Já estão prontas também as Emendas do Centrão, que são ao todo 10, em torno da Ordem Social e da Ordem Econômica. O Centrão começou a negociar as emenda com o Grupo dos 32. Os dois grupos poderão apresentar emendas em conjunto. O presidente da Constituinte está só esperando o fim do prazo de entrega de emendas para tentar um novo acordo com os líderes políticos. Ele quer aprovar os artigos do projeto de Constituição que não foram emendados. O senador Mansueto de Lavor procura Ulisses Guimarães para denunciar a falsificação da sua assinatura na emenda que prevê 5 anos para o mandato do Presidente Sarney. O senador declara que ele é favorável aos 4 anos do mandato.

Results of the Austrian-Ceylonese hydrobiological mission 1970 of the Institute of Zoology of the University of Vienna (Austria) and the Department of Zoology of the University of Sri Lanka, Vidyalankara Campus, Kelaniya. Pt. 19. Aquatic and semiaquatic Hemiptera of Sri Lanka from the Austrian Indo-Pacific expedition, 1970-71

This report concerns the aquatic and semiaquatic Hemiptera collected in Sri Lanka by Prof. Starmühlner and Prof. Costa during November and December 1970. A surprising number of new species have been found in the Starmühlner-Costa material, even in groups for which comprehensive revisions exist. Seven new species are described here.

DE-71-induced apoptosis involving intracellular calcium and the Bax-mitochondria-caspase protease pathway in human neuroblastoma cells In vitro

Polybrominated diphenyl ethers (PBDEs) are used extensively as flame-retardants and are ubiquitous in the environment and in wildlife and human tissue. Recent studies have shown that PBDEs induce neurotoxic effects in vivo and apoptosis in vitro. However, the signaling mechanisms responsible for these events are still unclear. In this study, we investigated the action of a commercial mixture of PBDEs (pentabrominated diphenyl ether, DE-71) on a human neuroblastoma cell line, SK-N-SH. A cell viability test showed a dose-dependent increase in lactate dehydrogenase leakage and 3-(4,5-dimethylthia-zol-2-yl)-2,5-diphenyl-tetrazolium bromide reduction. Cell apoptosis was observed through morphological examination, and DNA degradation in the cell cycle and cell apoptosis were demonstrated using flow cytometry and DNA laddering. The formation of reactive oxygen species was not observed, but DE-71 was found to significantly induce caspase-3, -8, and -9 activity, which suggests that apoptosis is not induced by oxidative stress but via a caspase-dependent pathway. We further investigated the intracellular calcium ([Ca2+](i)) levels using flow cytometry and observed an increase in the intracellular Ca2+ concentration with a time-dependent trend. We also found that the N-methyl d-aspartate (NMDA) receptor antagonist MK801 (3 mu M) significantly reduced DE-71-induced cell apoptosis. The results of a Western blotting test demonstrated that DE-71 treatment increases the level of Bax translocation to the mitochondria in a dose-dependent fashion and stimulates the release of cytochrome c (Cyt c) from the mitochondria into the cytoplasm. Overall, our results indicate that DE-71 induces the apoptosis of ([Ca2+](i)) in SK-N-SH cells via Bax insertion, Cyt c release in the mitochondria, and the caspase activation pathway.

Erratum: Generalized Smarr relation for Kerr-AdS black holes from improved surface integrals (Physical Review D (2005) 71 (044016)

SCOPUS: er.j