Model domains in C-3 with abelian automorphism group

It is shown that every hyperbolic rigid polynomial domain in C-3 of finite-type, with abelian automorphism group is equivalent to a domain that is balanced with respect to some weight.

Yb^3＋掺杂锌锗碲酸盐玻璃的热分析、光谱和激光性质

设计了组成为0．70TeO2-(0．20-x)ZnO-xGeO2—0．05La2O3-0．025K2O-0．025Na2O-0．01Yb2O3(摩尔分数x=0,0．05，0．10，0．15和0．20)的碲酸盐激光玻璃，测试了热学性质、吸收光谱、荧光光谱和荧光寿命。计算了Yb^3+离子的吸收截面、受激发射截面、荧光有效线宽等参数。结果表明，组成为0．70TeO2-0．20GeO2-0．05La2O3-0．025K2O-0．025Na2O的玻璃具有优于著名的碲锌钠(TZN)玻璃的热稳定性，高的受激发射截面(1

Trabajo y sociedad. Primer ciclo, módulo 3.

El sistema de educación a distancia propuesto por el Centro Nacional de Educación Básica a Distancia (CENEBAD) programa la enseñanza básica de adultos en tres ciclos. Este libro de texto corresponde al tercer módulo del primer ciclo. Se centra en el tema 'Trabajo y sociedad' que se estructura en cuatro unidades didácticas en las que se abordan contenidos de las áreas de lenguaje, matemáticas, ciencias sociales y ciencias de la naturaleza.

Sociedad y cultura. Tercer ciclo, módulo 3.

Libro de texto correspondiente al tercer módulo del tercer ciclo del programa de educación de adultos propuesto por el Centro Nacional de Educación Básica a Distancia (CENEBAD). Este módulo aborda la influencia que la sociedad y la cultura ejercen en la persona estructurándo el tema en cuatro unidades didácticas que, de forma interdisciplinar, abarcan contenidos de las áreas de lengua, matemáticas, ciencias naturales y ciencias sociales. La obra de lectura que debe leer el alumno como complemento es 'Del Miño al Bidasoa' de Camilo José Cela.

Matemáticas (3). Tercer curso.

La obra forma parte de un conjunto de materiales didácticos que tienen la finalidad de facilitar a los profesores el desarrollo del nuevo currículo, ofreciendo propuestas de programación y unidades didácticas. Se trata de materiales con cierto carácter experimental, que se adaptan a un esquema general propuesto por el Centro de Desarrollo Curricular del MEC. Este trabajo está basado en la experiencia desarrollada en el I.E.S. María Zambrano. La programación consta de cinco núcleos temáticos: Números, Algebra, Gráficos y funciones, Estadística y azar, y Geometría. En cada uno se especifican las unidades de las que consta, temporalización, orientaciones metodológicas e indicaciones para la evaluación. Cada unidad contiene los correspondientes conocimientos previos, objetivos, contenidos, actividades, recursos didácticos y ejemplos y ejercicios para su desarrollo. También desarrolla por completo la unidad 'Figuras geométricas: del plano al espacio'.

Música (3). Tercer curso.

Se presenta un material didáctico orientado al profesorado de Educación Secundaria Obligatoria (E.S.O.) que imparte la asignatura de música. De forma genérica se analiza la programación propuesta, especificando los objetivos perseguidos, los contenidos, la metodología a seguir, los temas transversales que se abordan, los recursos necesarios y las orientaciones para la evaluación. El proyecto se estructura en seis unidades didácticas que, de forma progresiva, acercan al alumno al aprendizaje musical. Para cada unidad didáctica se presentan los objetivos, contenidos, actividades que la conforman y sesiones en las se divide y los recursos necesarios para su desarrollo. Se adjunta un casette con grabaciones para la primera unidad didáctica 'La música en nuestras vidas'..

Study of the ℤ3 symmetry in QCD at finite temperature and chemical potential using a worm algorithm

Traditional Monte Carlo simulations of QCD in the presence of a baryon chemical potential are plagued by the complex phase problem and new numerical approaches are necessary for studying the phase diagram of the theory. In this work we consider a ℤ3 Polyakov loop model for the deconfining phase transition in QCD and discuss how a flux representation of the model in terms of dimer and monomer variable solves the complex action problem. We present results of numerical simulations using a worm algorithm for the specific heat and two-point correlation function of Polyakov loops. Evidences of a first order deconfinement phase transition are discussed. © 2013 American Institute of Physics.

Adjuvant bevacizumab-containing therapy in triple-negative breast cancer (BEATRICE): primary results of a randomised, phase 3 trial

BACKGROUND The addition of bevacizumab to chemotherapy improves progression-free survival in metastatic breast cancer and pathological complete response rates in the neoadjuvant setting. Micrometastases are dependent on angiogenesis, suggesting that patients might benefit from anti-angiogenic strategies in the adjuvant setting. We therefore assessed the addition of bevacizumab to chemotherapy in the adjuvant setting for women with triple-negative breast cancer. METHODS For this open-label, randomised phase 3 trial we recruited patients with centrally confirmed triple-negative operable primary invasive breast cancer from 360 sites in 37 countries. We randomly allocated patients aged 18 years or older (1:1 with block randomisation; stratified by nodal status, chemotherapy [with an anthracycline, taxane, or both], hormone receptor status [negative vs low], and type of surgery) to receive a minimum of four cycles of chemotherapy either alone or with bevacizumab (equivalent of 5 mg/kg every week for 1 year). The primary endpoint was invasive disease-free survival (IDFS). Efficacy analyses were based on the intention-to-treat population, safety analyses were done on all patients who received at least one dose of study drug, and plasma biomarker analyses were done on all treated patients consenting to biomarker analyses and providing a measurable baseline plasma sample. This trial is registered with ClinicalTrials.gov, number NCT00528567. FINDINGS Between Dec 3, 2007, and March 8, 2010, we randomly assigned 1290 patients to receive chemotherapy alone and 1301 to receive bevacizumab plus chemotherapy. Most patients received anthracycline-containing therapy; 1638 (63%) of the 2591 patients had node-negative disease. At the time of analysis of IDFS, median follow-up was 31·5 months (IQR 25·6-36·8) in the chemotherapy-alone group and 32·0 months (27·5-36·9) in the bevacizumab group. At the time of the primary analysis, IDFS events had been reported in 205 patients (16%) in the chemotherapy-alone group and in 188 patients (14%) in the bevacizumab group (hazard ratio [HR] in stratified log-rank analysis 0·87, 95% CI 0·72-1·07; p=0·18). 3-year IDFS was 82·7% (95% CI 80·5-85·0) with chemotherapy alone and 83·7% (81·4-86·0) with bevacizumab and chemotherapy. After 200 deaths, no difference in overall survival was noted between the groups (HR 0·84, 95% CI 0·64-1·12; p=0·23). Exploratory biomarker assessment suggests that patients with high pre-treatment plasma VEGFR-2 might benefit from the addition of bevacizumab (Cox interaction test p=0·029). Use of bevacizumab versus chemotherapy alone was associated with increased incidences of grade 3 or worse hypertension (154 patients [12%] vs eight patients [1%]), severe cardiac events occurring at any point during the 18-month safety reporting period (19 [1%] vs two [<0·5%]), and treatment discontinuation (bevacizumab, chemotherapy, or both; 256 [20%] vs 30 [2%]); we recorded no increase in fatal adverse events with bevacizumab (four [<0·5%] vs three [<0·5%]). INTERPRETATION Bevacizumab cannot be recommended as adjuvant treatment in unselected patients with triple-negative breast cancer. Further follow-up is needed to assess the potential effect of bevacizumab on overall survival.

Na 1 Nachlass Max Horkheimer, 74 - Korrespondenzen u.a. mit Käte von Hirsch (p. II 8, 232-369)

1 Brief von F. Pollock an Frederick J. Hacker, 1945; 1 Brief von Frederick J. Hacker an Max Horkheimer, sowie 2 Memoranden von Max Horkheimer; 5 Briefe zwischen Willy Hartner und Max Horkheimer, 1948; 3 Briefe und eine Drucksache von Fred Herzberg an Max Horkheimer, 1947; 1 Brief und 3 Memoranden von Max Horkheimer an Fred Herzberg, 1947; 2 Briefe von Heinz Herald an Max Horkheimer, 1946 sowie 1 Gutachten und Beilage von Max Horkheimer an Heinz Herald, 1946; 2 Briefe zwischen Josef Haurand und Max Horkheimer, 1949, 1950; 3 Briefe und Beilage zwischen Herta Herzog und Max Horkheimer, 1949; 23 Briefe zwischen dem Hessischen Staatsministerium für Kultus und Unterricht und Max Horkheimer, 1948-1949 siehe auch Hessischer Minister für Erziehung und Volkdsbildung; 2 Briefe von Eduard Heumann an Max Horkheimer, 1948-1949; 1 Brief und Beilage von George J. Hexter an A. Lourie; 35 Briefe zwischen Käte von Hirsch und Max Horkheimer, 1941-1948;

Ostracoda in sediment core CRP-3 from the Ross Sea, Antarctica

A total of eighteen species of marine ostracods, in at least twelve genera, have been recovered from Early and Late Oligocene glacio-marine sediments from boreholes CRP-3 and CRP-2/2A in the Victoria Land Basin, Ross Sea, Antarctica. Faunas are sparse and generally moderately-well preserved. Previously, three species or closely related species have been recorded only from glacial settings (Kuiperiana meridionalislain (Müller), Australicythere polylyca (Müller), Hemicytheridea aff. H. kinggeorgeensis Blaszyk), but palaeotemperatures somewhat higher than at present in the Ross Sea are suggested by the presence of Austrocythere reticulotuberculata Hartmann, Cluthia aff. C. antiqua Ayress & Drapala and Cytherella? sp. 4796. Majungaella sp. 4471 is an enigmatic component, representing a genus previously known only from warm Cretaceous and Eocene, and relatively warm interglacial Pliocene habitats in southern Gondwana and the Antarctic Peninsula. Palaeobiogeographical considerations indicate that during Early Oligocene times, the Ross Sea area had faunal links with both Antarctic Peninsula/South America and southern Australasia. Three species present in the Early Oligocene glacial environments at Cape Roberts have survived to the Recent in the cool-cold Antarctic/Sub-Antarctic region: Austrocythere reticulotuberculata Hartmann, Australicythere polylyca (Müller), and Kuiperiana meridionalis (Müller).

Solar radiation over and under sea ice and photographic quantification of Ice algal aggregates during the POLARSTERN cruise ARK-XXVII/3 (IceArc) in summer 2012

The ice cover of the Arctic Ocean has been changing dramatically in the last decades and the consequences for the sea-ice associated ecosystem remain difficult to assess. Algal aggregates underneath sea ice have been described sporadically but the frequency and distribution of their occurrence is not well quantified. We used upward looking images obtained by a remotely operated vehicle (ROV) to derive estimates of ice algal aggregate biomass and to investigate their spatial distribution. During the IceArc expedition (ARK-XXVII/3) of RV Polarstern in late summer 2012, different types of algal aggregates were observed floating underneath various ice types in the Central Arctic basins. Our results show that the floe scale distribution of algal aggregates in late summer is very patchy and determined by the topography of the ice underside, with aggregates collecting in dome shaped structures and at the edges of pressure ridges. The buoyancy of the aggregates was also evident from analysis of the aggregate size distribution. Different approaches used to estimate aggregate biomass yield a wide range of results. This highlights that special care must be taken when upscaling observations and comparing results from surveys conducted using different methods or on different spatial scales.

Particulate and phytoplankton absorption during POLARSTERN cruises ANT-XXVI/3 and ANT-XXVIII/3

The euphotic depth (Zeu) is a key parameter in modelling primary production (PP) using satellite ocean colour. However, evaluations of satellite Zeu products are scarce. The objective of this paper is to investigate existing approaches and sensors to estimate Zeu from satellite and to evaluate how different Zeu products might affect the estimation of PP in the Southern Ocean (SO). Euphotic depth was derived from MODIS and SeaWiFS products of (i) surface chlorophyll-a (Zeu-Chla) and (ii) inherent optical properties (Zeu-IOP). They were compared with in situ measurements of Zeu from different regions of the SO. Both approaches and sensors are robust to retrieve Zeu, although the best results were obtained using the IOP approach and SeaWiFS data, with an average percentage of error (E) of 25.43% and mean absolute error (MAE) of 0.10 m (log scale). Nevertheless, differences in the spatial distribution of Zeu-Chla and Zeu-IOP for both sensors were found as large as 30% over specific regions. These differences were also observed in PP. On average, PP based on Zeu-Chla was 8% higher than PP based on Zeu-IOP, but it was up to 30% higher south of 60°S. Satellite phytoplankton absorption coefficients (aph) derived by the Quasi-Analytical Algorithm at different wavelengths were also validated and the results showed that MODIS aph are generally more robust than SeaWiFS. Thus, MODIS aph should be preferred in PP models based on aph in the SO. Further, we reinforce the importance of investigating the spatial differences between satellite products, which might not be detected by the validation with in situ measurements due to the insufficient amount and uneven distribution of the data.