993 resultados para 366.38
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Censorship and Performance, edited by Tom Sellar, examines the politics of censorship, and continuing contests over the ‘right’ to claim theatrical and cultural stages for controversial forms of social and self representation, at the start of the twenty-first century. In bringing this collection together, Sellar has taken a broad-based approach to the concept of censorship in theatrical performance—and, indeed, to the concept of theatrical performance itself. Sellar and his contributors clearly accept that surveillance, suppression and restriction of specific forms of representation is a complex, culturally specific phenomenon. In this sense, Censorship and Performance addresses direct political control over content, as well as thornier arguments about media controversy, moral panic, and the politics of self-censorship amongst artists and arts organisations.
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Genetic polymorphisms in hepatically expressed UGT1A1 and UGT1A9 contribute to the interindividual variability i-n irinotecan disposition and toxicity. We screened UGT1A1 (UGT1A1*60, g.−3140G>A, UGT1A1*28 and UGT1A1*6) and UGT1A9 (g.−118(T)9>10 and I399C>T) genes for polymorphic variants in the promoter and coding regions, and the genotypic effect of UGT1A9 I399C>T polymorphism on irinotecan disposition in Asian cancer patients was investigated. Blood samples were collected from 45 patients after administration of irinotecan as a 90 min intravenous infusion of 375 mg/m2 once in every 3 weeks. Genotypic–phenotypic correlates showed that cancer patients heterozygous or homozygous for the I399C>T allele had approximately 2-fold lower systemic exposure to SN-38 (P<0.05) and a trend towards a higher relative extent of glucuronidation (REG) of SN-38 (P>0.05). UGT1A1–1A9 diplotype analysis showed that patients harbouring the H1/H2 (TG6GT10T/GG6GT9C) diplotype had 2.4-fold lower systemic exposure to SN-38 glucuronide (SN-38G) compared with patients harbouring the H1/H5 (TG6GT10T/GG6GT10C) diplotype (P=0.025). In conclusion, this in vivo study supports the in vitro findings of Girard et al. and suggests that the UGT1A9 I399C>T variant may be an important glucuronidating allele affecting the pharmacokinetics of SN-38 and SN-38G in Asian cancer patients receiving irinotecan chemotherapy.
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Airports are a place of transition, empty halls of fleeting comings, goings and waitings. 'Gate 38' follows the experience of four groups of young people trapped at this point of departure. As contact with the outside world is cut off, the focus is placed squarely on what they’re doing, and where they’re going. A non-traditional musical set at the end of the world. Commissioned by MacGregor State High School's Centre of Artistic Development, script development included workshops with the CAD class of 2007. No musical score required.
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Raman spectra of the uranyl titanate mineral davidite-(La) (La,Ce)(Y,U,Fe2+)(Ti,Fe3+)20(O,OH)38 were analysed and related to the mineral structure. Observed bands are attributed to the TiO and (UO2)2+ stretching and bending vibrations, U-OH bending vibrations, H2O and (OH)- stretching, bending and libration modes. U-O bond lengths in uranyls and O-H…O bond lengths are calculated from the wavenumbers assigned to the stretching vibrations. Raman bands of davidite-(La) are in harmony with those of the uranyl oxyhydroxides. The mineral davidite-(La) is metamict as is evidenced by the intensity of the UO stretching and bending modes being of lower intensity than expected and with bands that are significantly broader.
Resumo:
Airports are a place of transition, empty halls of fleeting comings, goings and waitings. 'Gate 38' follows the experience of four groups of young people trapped at this point of departure. As contact with the outside world is cut off, the focus is placed squarely on what they’re doing, and where they’re going. A non-traditional musical set at the end of the world. Commissioned by MacGregor State High School's Centre of Artistic Development, script development included workshops with the CAD class of 2007. No musical score required.
Context-specific stressors, work-related social support and work-family conflict : a mediation study
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Understanding the antecedents of work-family conflict is important as it allows organisations to effectively engage in work design for professional employees. This study examines the impact of sources of social support as antecedents of work-family conflict. The hypotheses were tests using Partial Least Squares modelling on a sample of 366 professional employees. The path model showed that context-specific stressors impacted positively on job demand, which led to higher levels of work-family conflict. Contrary to our expectation, non-work related social support did not have any statistical relationship with job demand and work-family conflict. In addition, individuals experiencing high job demands were found to obtain more social support from both work and non-work-related sources. Individuals with more work-related social support were less likely to have less work-family conflict. Surprisingly, non-work social support sources had no statistically significant relationship with work-family conflict.
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Abstract: We report the growth and the electron cyclotron resonance measurements of n-type Si/Si0.62Ge0.38 and Si0.94Ge0.06/Si0.62Ge0.38 modulation-doped heterostructures grown by rapid thermal chemical vapor deposition. The strained Si and Si0.94Ge0.06 channels were grown on relaxed Si0.62Ge0.38 buffer layers, which consist of 0.6 mu m uniform Si0.62Ge0.38 layers and 0.5 mu m compositionally graded relaxed SiGe layers from 0 to 38% Ge. The buffer layers were annealed at 800 degrees C for 1 h to obtain complete relaxation. A 75 Angstrom Si(SiGe) channel with a 100 Angstrom spacer and a 300 Angstrom 2 X 10(19) cm(-3) n-type supply layer was grown on the top of the buffer layers. The cross-sectional transmission electron microscope reveals that the dense dislocation network is confined to the buffer layer, and relatively few dislocations terminate on the surface. The plan-view image indicates the threading dislocation density is about 4 X 10(6) cm(-2). The far-infrared measurements of electron cyclotron resonance were performed at 4 K with the magnetic field of 4-8 T. The effective masses determined from the slope of the center frequency of the absorption peak versus applied magnetic field plot are 0.203m(0) and 0.193m(0) for the two dimensional electron gases in the Si and Si0.94Ge0.06 channels, respectively. The Si effective mass is very close to that of a two dimensional electron gas in an Si MOSFET (0.198m(0)). The electron effective mass of Si0.94Ge0.06 is reported for the first time and is about 5% lower than that of pure Si.
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Article 38(1) of the Statute of International Court of Justice (hereinafter ICJ) is today generally seen as a direction to the significant sources of international law, which the world court must consider in resolving disputes; however, the list is not exhaustive nor encompasses all the formal and material sources of the international legal system. Article 38 of the Statute of ICJ was written ninety years ago in a different world, a question is under debate in many states, whether or not sources mentioned in Article 38 of the statute are compatible with needs of 21st century ? In recent decade, many new actors come on the stage which have transformed international law and now it is not only governs relations among states but also covers many International Organizations. Article 38(2) does refer to the other possible sources but does not define them. Moreover, law is a set of rules that citizens must follow to regulate peace and order in society. These laws are binding on both the individual and the state on a domestic and international level. Do states regard this particular rule as a rule of international law? The modern legal system of states is in the form of a specified and well organized set of rules, regulating affairs of different organs of a state. States also need a body of rules for their intercourse with each other. These sets of rules among states are called “International Law.” This article examines international law, its foundation and sources. It considers whether international conventions and treaties can be the only way states can considerably create international law, or there is a need for clarity about the sources of international law. Article is divided into two parts, the first one deals with sources of international law discussed in Article 38 of the statute of International Court of Justice whereas the second one discusses the material and formal sources of law, which still need reorganization as sources of law.
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Migraine is a debilitating neurological disorder affecting around 1 in 7 people worldwide, but its molecular mechanisms remain poorly understood. Some debate exists over whether migraine is a disease of vascular dysfunction, or a result of neuronal dysfunction with secondary vascular changes. Genome-wide association (GWA) studies have thus far identified 13 independent loci associated with migraine. To identify new susceptibility loci, we performed the largest genetic study of migraine to date, comprising 59,674 cases and 316,078 controls from 22 GWA studies. We identified 45 independent single nucleotide polymorphisms (SNPs) significantly associated with migraine risk (P < 5 x 10-8) that map to 38 distinct genomic loci, including 28 loci not previously reported and the first locus identified on chromosome X. Furthermore, a subset analysis for migraine without aura (MO) identified seven of the same loci as from the full sample, whereas no loci reached genome-wide significance in the migraine with aura (MA) subset. In subsequent computational analyzes, the identified loci showed enrichment for genes expressed in vascular and smooth muscle tissues, consistent with a predominant theory of migraine that highlights vascular etiologies.
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CaO-SiO2-FeOx-P2O5-MgO bearing slags are typical in the basic oxygen steelmaking (BOS) process. The partition ratio of phosphorus between slag and steel is an index of the phosphorus holding capacity of the slag, which determines the phosphorus content achievable in the finished steel. The influences of FeO concentration and basicity on the equilibrium phosphorus partition ratios were experimentally determined at temperatures of 1873 and 1923 K, for conditions of MgO saturation. The partition ratio initially increased with basicity but attained a constant value beyond basicity of 2.5. An increase in FeO concentration up to approximately 13 to 14 mass pet was beneficial for phosphorus partition.
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We report the far-infrared measurements of the electron cyclotron resonance absorption in n-type Si/Si0. 62Ge0.38 and Si0.94Ge0.06 /Si0. 62Ge0.38 modulation- doped heterostructures grown by rapid thermal chemical vapor deposition. The strained Si and Si0.94Ge0.06 channels were grown on relaxed Si0.62Ge0.38 buffer layers, which consist of 0.6 μm uniform Si0.62Ge0.38 layers and 0.5 μm compositionally graded relaxed SiGe layers from 0% Ge to 38 % Ge. The buffer layers were annealed at 800 °C for 1 hr to obtain complete relaxation. The samples had 100 Å spacers and 300 Å 2×1019 cm-3 n-type supply layers on the tops of the 75 Å channels. The far-infrared measurements of electron cyclotron resonance were performed at 4K with the magnetic field of 4 – 8 Tesla. The effective masses determined from the slope of center frequency of absorption peak vs applied magnetic field plot are 0.20 mo and 0.19 mo for the two dimensional electron gases in the Si and Si0.94Ge0.06 channels, respectively. The Si effective mass is very close to that of two dimensional electron gas in Si MOSFET (0.198mo). The electron effective mass of Si0.94Ge0.06 is reported for the first time and about 5 % lower than that of pure Si.
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El dióxido de carbono es el más importante de los Gases de Efecto Invernadero, por la actividad humana, tanto en términos de su cantidad como de su potencial efecto sobre el calentamiento global. Este es producido cuando se usa combustible fósil para generar energía y cuando los bosques son deforestados y quemados. La vegetación arbórea es una fuente y a la vez un sumidero natural de CO2. El presente estudio se realizó en el municipio de Nandaime departamento de Granada 20 10, con el objetivo de evaluar el carbono almacenado en los componentes biomasa aérea, hojarasca y suelo en tres sucesiones de edad (9, 15 y 19 años), en bosque seco tropical. Se hizo un inventario forestal (fustal 200 m2 y latizal 25 m2). Se cortó el árbol promedio en fustales Se pesó y muestreo la biomasa aérea y hojarasca, en las cuales se determinó en laboratorio el porcentaje de humedad y contenido de carbono. La mayor cantidad de árboles fue en la edad de 9 años con 2,366.7 árboles/ha. Los promedios de diámetro en fustal fueron 10.92, 14.7 y 15.97 cm, para 9, 15 y 19 años respectivamente. Los promedios de diámetro en latizal fueron 6.29, 6.41 y 6.43 cm, para 9 15 y 19 años respectivamente. Los promedios de altura en fustal fueron 6.92, 10.21 y 10.78 m, para 9 15 y19 años respectivamente. Los promedios de altura en latizal fueron 5.25, 6.00 y 8.13 m, para 9 15 y19 años respectivamente. La mayor cantidad de área basal y volumen fue en la edad de 9 años con 38.66 m 2/a y 356.83 m3/ha. Según el índice de diversidad Shannon-Wiener y Simpson se determinó que el sitio más diverso en fustal fue la sucesión de 15 años de edad y el menos diverso el nivel de 19 años, en latizal el más diverso fue el de 15 años y el menos diverso el de 19. En la edad 19 años , se cuantifico la mayor cantidad de hojarasca con 5.69 t/ha, pero el mayor contenido de carbono fue en 9 años con 1.11 t/ha. En la edad 9 años, se cuantifico la mayor cantidad de biomasa y carbono en ramas y hojas con 206.82 y 37.49t/ha, respectivamente. Para fuste, se cuantifico la mayor cantidad de biomasa y carbono en la edad de 9 años con 149.98 y 47.63 t/ha, respectivamente. El carbono almacenado en el suelo fueron 22.5, 27.68 y 42.39 t/ha, para 9, 15 y19 años respectivamente. La tasa de fijación de la biomasa aérea fue 9.46, 7.11 y 6.23 t/año, para 9, 15 y 19 años respectivamente.
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Con el objetivo de darle seguimiento al manejo de Plutella xylostella (L) considerada como plaga principal del cultivo del repollo (Brassica oleracea (L), Se evaluó el efecto que ejercen las temperaturas sobre el aislado 38/87 de Beauveria bassiana. (Bals) Vuill, realizado en el laboratorio de control microbial de la Universidad Nacional Agraria, (U.NA). Managua, Nicaragua. Las temperaturas evaluadas fueron 23, 25, 26, 28, 30 °C. con 75% de humedad relativa y una misma concentración 10º conidias/ml aplicando las conidias a las larvas por el método de inmersión y aspersión de las hojas de repollo. La prueba de Tukey estableció diferencias significativas entre tratamientos siendo la temperatura de 26ºc la más óptima en la mortalidad de larvas, para ambos métodos, con porcentajes de mortalidad por aspersión de 87.2% e inmersión con 81.7%, seguido de las temperaturas de 30ºC con 73.4% inmersión y 70.9% aspersión. Los valores más bajos del ensayo se obtuvieron con un porcentaje de 37.0% para la temperatura de 23ºC por el método de aspersión. El análisis de varianza realizado para determinar el nivel de significancia entre ambos métodos de aplicación, resultó con diferencias Significativas. El método de aplicación influye en los resultados de bioensayos. Se encontró que la inoculación de larvas por inmersión resulta más eficiente en la mortalidad de larvas. Los valores de TL50(tiempo letal medio) variaron en dependencia de la temperatura siendo el TL50 más bajo en la temperatura de 30ºC por el método de inmersión con O.72 días después de la inoculación , seguida de la temperatura de 26ºC con 2.52 días después de la inoculación. Por el método de aspersión se obtuvo mejores resultados en las temperaturas de 26 y 28ºC con 1.15 y 6.37 días. respectivamente.