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We recently mapped the belt mutation in Brown Swiss cattle to a 922 kb interval on BTA3. In this study, we analysed two additional cattle breeds with the belted phenotype: Galloway and Dutch Belted (Lakenvelder). By genotyping microsatellites in solid-coloured and belted Galloways, we confirmed that the belt mutation in Galloways is strongly associated with the same chromosomal locus as in Brown Swiss cattle. Subsequently, we analysed 36 SNPs in the belt interval in three breeds. We identified a single belt-associated haplotype for each of the analysed breeds. The three breed-specific belt haplotypes share alleles in four blocks. Three of these blocks comprise only one single or two consecutive markers, while the largest shared haplotype block encompasses nine consecutive SNPs in a 336 kb interval. The large shared haplotype across divergent breeds suggests a common mutation for the belt phenotype in all three breeds. We identified a potential candidate gene within this interval coding for the developmental transcription factor HES6. We re-sequenced the complete HES6 coding sequence in belted and solid-coloured cattle but did not find belt-associated polymorphisms. In conclusion, our data provide strong evidence in favour of a common founder for the belt phenotype in different cattle breeds and have resulted in an improved fine-mapping of the causative mutation.

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u.a.: Klage über die Einsamkeit in der Provinz; Ferdinand Laban; Arthur Schopenhauer;

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Frankfurter Dialekttheater, Wilhelm Sauerwein: "Der Gräff, wie er leibt und lebt", "Gräff im Grünen", "Der Amerikaner", Carl Malß, Pfeifer: "Die Brunnenfahrt", Sauerwein: Briefe an Wilhelm Rieger (verloren), Collegzeitung, Geplante Sauerwein-Gesamtausgabe

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126 Briefe zwischen Max Horkheimer und Leo Löwenthal, Januar - August 1948; 1 Brief von Max Horkheimer an Herbert Marcuse, 1948; 2 Briefe zwischen Theodor W. Adorno und Leo Löwenthal, 1948; 1 Brief von Leo Löwenthal an Samuel H. Flowerman, 15.06.1948; 3 Briefe zwischen Erich Preiser und Leo Löwenthal, 1948; 1 Brief von Max Horkheimer an Howard Wilson, 28.08.1948; 1 Brief von Paul Lazarsfeld an Leo Löwenthal, 26.08.1948; 1 Brief von Käte Hirsch an Leo Löwenthal, [1948]; 1 Brief von Willy Haas an Max Horkheimer, 15.07.1948; 1 Brief von Max Horkheimer an Moses Finley, 16.08.1948; 1 Brief von Max Horkheimer an Robert J. Havighurst, [August 1948]; 1 Brief (Auszug) von Hans Mayer an Max Horkheimer, 23.03.1948; 1 Brief von Julius Schwietering an Max Horkheimer, 18.02.1948; 1 Brief von E. Stein an Max Horkheimer, 26.06.1948;

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Fil: Banzato, Guillermo. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

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Fil: Banzato, Guillermo. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.

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