Marguerite Tolbert Papers - Accession 203

Marguerite Tolbert (1893-1982) was a Winthrop alumna (class of 1914), club woman, and administrator with the Opportunity School in Columbia, South Carolina. The Marguerite Tolbert Papers consist of correspondence, manuscripts, galley proofs, biographical sketches, newspaper clippings, and other records relating to the publication of the book, South Carolina’s Distinguished Women of Laurens County. Miss Tolbert served as coordinator for the book project. Also included is an unpublished manuscript written by Clara Yarborough concerning the terms of office of seven former South Carolina governors. Miss Yarborough served as secretary under these governors.

Loss of tumor suppressor mir-203 mediates overexpression of LIM and SH3 Protein 1 (LASP1) in high-risk prostate cancer thereby increasing cell proliferation and migration

Several studies have linked overexpression of the LIM and SH3 domain protein 1 (LASP1) to progression of breast, colon, liver, and bladder cancer. However, its expression pattern and role in human prostate cancer (PCa) remained largely undefined. Analysis of published microarray data revealed a significant overexpression of LASP1 in PCa metastases compared to parental primary tumors and normal prostate epithelial cells. Subsequent gene-set enrichment analysis comparing LASP1-high and -low PCa identified an association of LASP1 with genes involved in locomotory behavior and chemokine signaling. These bioinformatic predictions were confirmed in vitro as the inducible short hairpin RNA-mediated LASP1 knockdown impaired migration and proliferation in LNCaP prostate cancer cells. By immunohistochemical staining and semi-quantitative image analysis of whole tissue sections we found an enhanced expression of LASP1 in primary PCa and lymph node metastases over benign prostatic hyperplasia. Strong cytosolic and nuclear LASP1 immunoreactivity correlated with PSA progression. Conversely, qRT-PCR analyses for mir-203, which is a known translational suppressor of LASP1 in matched RNA samples revealed an inverse correlation of LASP1 protein and mir-203 expression. Collectively, our results suggest that loss of mir-203 expression and thus uncontrolled LASP1 overexpression might drive progression of PCa.

Ms. hebr. oct. 203 - [Sammelband in 10 Teilen: Handschriftenkonvolut]

Vorbesitzer: N. Brüll

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 203 - Kritische Nachfragen von Dr. jur. Hermann Georg Du Roi zur Ethik im 2. Band der "Welt als Wille und Vorstellung"

u.a.: Stellung der Ethik in der Parerga und Paralipomena, 2. Band;

Ms.Ff.F.Stoltze 3. 203 - Brief von Emil Neubürger an Friedrich Stoltze

Zu einem Besuch Stoltzes

Ausst. 203 - Passio Christi ab Alberto Durer Nurenbergensi effigiata cu[m] varij generis carminibus Fratris Benedicti Chelidonij Musophili

Vorbesitzer: Heinrich Anton Cornill-d'Orville (Exlibris im Vorderdeckel)

Na 1 Nachlass Max Horkheimer, 576 - Korrespondenzen mit Friedrich (Frederick) Pollock (p. VI 32, 1-203)

1 Brief von Frederick Pollock an Robert M. MacIver, [1941]; 1 Brief von Max Horkheimer an Lou Eisler, 06.11.1941; 1 Brief von Paul Guggenheim an Frederick Pollock, 20.10.1941; 1 Brief von der Library of Congress (Washington) an Frederick Pollock, 19.10.1941; 1 Brief von S. Lorris an Frederick Pollock, 15.10.1941; 1 Brief von Frederick Pollock an Glidden Buick, 22.09.1941; 1 Brief von Margot von Mendelssohn an das Department of State (Washington), 02.09.1941; 1 Brief von Stephen Duggan an Frederick Pollock, 07.08.1941;

Ms. lat. oct. 203 - La Cortona convertita

Vorbesitzer: Michelangelo Gualandi

Carlo Gisnburg. Mitos, emblemas, indicios. Morfología e historia. España, Gedisa, 1989, 203 p.

Fil: Bragoni, Beatriz.

Element oxides in basaltic glass fragments from ODP Hole 203-1243B

Sand-sized basaltic glass fragments were recovered in the liner of Core 203-1243B-19R, the deepest recovery from Hole 1243B. Microprobe analysis of 582 glassy cuttings cluster into five compositionally distinct groups, most of which are unlike the lithologic units described on board ship. Drilling operations intended to sweep cuttings from the caving hole and differences between the cuttings and geochemically distinct lithologic units of the upper part of the basement indicate that the cuttings came mainly, if not entirely, from the lower part of the hole. They give information about the part of Hole 1243B that had poor core recovery. Enriched mid-ocean-ridge basalt (MORB) from the upper part of the hole and transitional MORB from two groups of cuttings from sources low in the hole may be a trace of the Galápagos plume on the Pacific plate or may be a normal consequence of eruptions from two distinct magmas on fast-spreading crust.