(Table T1) Calcium carbonate mineralogy and stable isotopic composition of ODP Hole 182-1132C sediments

Petrographic observation and carbonate mineralogic and stable isotopic investigation were conducted on lower Oligocene to middle Miocene sediments recovered during Ocean Drilling Program Leg 182 from Site 1132, located at a water depth of 218.5 m immediately seaward of the shelf-slope break of the eastern Eyre Terrace in the western Great Australian Bight. The middle Miocene section consists of bioclastic packstone and grainstone with an interval of partially silicified nannofossil-foraminiferal chalk and is slightly to densely dolomitized. By contrast, the lower Oligocene to lower Miocene section is characterized by a predominance of planktonic and benthic foraminifers, high porosity, absence of chert, and weak dolomitization. The carbon and oxygen isotopic composition of calcites and dolomites between two sections, however, shows no significant difference.

Planktonic foraminiferal stratigraphy and datum levels of ODP Leg 182 sites

Planktonic foraminifers from Ocean Drilling Program Leg 182, Holes 1126B and 1126C, 1128B and 1128C, 1130A and 1130B, 1132B, and 1134A and 1134B confirm the neritic record that during the early Miocene the Great Australian Bight region was in a cool-temperate regime with abundant Globoturborotalita woodi. Warm marine environments started to develop in the later part of the early Miocene, and the region became warm temperate to subtropical in the early middle Miocene with abundant Globigerinoides, Orbulina, and Globorotalia, corresponding to global warming at the Miocene climatic optimum. Fluctuations between cool- and warm-temperate conditions prevailed during the late Miocene, as indicated by abundant Globoconella conoidea and Menardella spp. A major change in planktonic foraminiferal assemblages close to the Miocene/Pliocene boundary not only drove many Miocene species into extinction but also brought about such new species as Globorotalia crassaformis and Globoconella puncticulata. Warm-temperate environments continued into the early and mid-Pliocene before being replaced by cooler conditions, supporting numerous Globoconella inflata and Globigerina quinqueloba. Based on data from this study and published results from the Australia-New Zealand region, we established a local planktonic foraminifer zonation scheme for separating the southern Australian Neogene (SAN) into Zones SAN1 to SAN19 characterizing the Miocene and Zones SAN20 to SAN25 characterizing the Pliocene. The Neogene sections from the Great Australian Bight are bounded by hiatuses of ~0.5 to >3 m.y. in duration, although poor core recovery in some holes obscured a proper biostratigraphic resolution. A total of 15 hiatuses, numbered 1 to 15, were identified as synchronous events from the base of the Miocene to the lower part of the Pleistocene. We believe that these are local manifestations of major third-order boundaries at about (1) 23.8, (2) 22.3, (3) 20.5, (4) 18.7, (5) 16.4, (6) 14.8, (7) 13.5, (8) 11.5, (9) 9.3, (10) 7.0, (11) 6.0, (12) 4.5, (13) 3.5, (14) 2.5, and (15) 1.5 Ma, respectively. This hiatus-bounded Neogene succession samples regional transgressions and stages of southern Australia and reveals its stepwise evolutionary history.

(Table 1) Porewater analysis with respect to gypsum from different ODP holes

The stability of gypsum in marine sediments has been investigated through the calculation of its saturation index at the sediment in situ temperature and pressure, using the entire ODP/IODP porewater composition database (14416 samples recovered from sediments collected during 95 ODP and IODP Legs). Saturation is reached in sediment porewaters of 26 boreholes drilled at 23 different sites, during 12 ODP/IODP Legs. As ocean bottom seawater is largely undersaturated with respect to gypsum, the porewater Ca content or its SO4 concentration, or both, must increase in order to reach equilibrium. At several sites equilibrium is reached either through the presence of evaporitic gypsum layers found in the sedimentary sequence, and/or through a salinity increase due to the presence of evaporitic brines with high concentrations of Ca and SO4. Saturation can also be reached in porewaters of seawater-like salinity (~ 35 per mil), provided sulfate reduction is limited. In this case, saturation is due to the alteration of volcanogenic material which releases large amounts of Ca to the porewaters, where the Ca concentration can reach 55 times its seawater value as for example at ODP Leg 134 site 833. At a few sites, saturation is reached in hydrothermal environments, or as a consequence of the alteration of the basaltic basement. In addition to the well known influence of brines on the formation of gypsum, these results indicate that the alteration of sediments rich in volcanogenic material is a major process leading to gypsum saturation in marine sediment porewaters. Therefore, the presence of gypsum in ancient and recent marine sediments should not be systematically interpreted as due to hypersaline waters, especially if volcanogenic material is present.

MCF7/LCC2: A 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780

The development of resistance to the antiestrogen tamoxifen occurs in a high percentage of initially responsive patients. We have developed a new model in which to investigate acquired resistance to triphenylethylenes. A stepwise in vitro selection of the hormone-independent human breast cancer variant MCF-7/LCC1 against 4-hydroxytamoxifen produced a stable resistant population designated MCF7/LCC2. MCF7/LCC2 cells retain levels of estrogen receptor expression comparable to the parental MCF7/LCC1 and MCF-7 cells. Progesterone receptor expression remains estrogen inducible in MCF7/LCC2 cells, although to levels significantly lower than observed in MCF-7 and MCF7/LCC1 cells. MCF7/ LCC2 cells form tumors in ovariectomized nude mice without estrogen supplementation, and these tumors are tamoxifen resistant but can be tstrogen stimulated. Significantly, MCF7/LCC2 cells have retained sensitivity to the steroidal antiestrogen ICI 182,780. These data suggest that some breast cancer patients who acquire resistance to tamoxifen may not develop cross-resistance to treatment with steroidal antiestrogens.

Plan otvoda zemli kollektiva "Poltavt︠s︡y" Krivorogskogo okruga Sofievskogo raĭona ploshchadiʻ︠u︡ 182 desi︠a︡tiny

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Plan otvoda zemli kollektiva "Poltavt︠s︡y" Krivorogskogo okruga Sofievskogo raĭona ploshchadiʻ︠u︡ 182 desi︠a︡tiny

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Sapientia, 1991, Vol. XLVI, nº 182 (número completo)

Contenido: Capacidad de la mente humana para alcanzar el ser de las cosas, hasta el mismo Esse Subsistens (IV) / Octavio Nicolás Derisi – Nuestro conocimiento real de Dios y los enunciados teológicos / Juan A. Casaubón – Saber divino y saber humano de la negatividad y del mal / Joseph de Finance – La vigencia de los principios de Santo Tomás de Aquino concernientes a la moralidad de la guerra / Mario E. Sacchi – Notas para una metodología jurídica realista a partir de una lectura de Tomás de Aquino / Renato Rabbi-Baldi Cabanillas – Notas y comentarios -- Bibliografía

Diário da Constituinte [gravação de vídeo] : [programa n. 182]

O atual projeto de Constituição propõe um sistema misto de governo, com a existência do presidente, como chefe de Estado, e do primeiro-ministro, chefe da administração federal. A proposta não agrada os presidencialistas. Deputado Wagner Lago (PMDB-MA) diz que o parlamentarismo pressupõe partidos políticos fortes e uma burocracia estatal eficiente, o que não é caso do Brasil. O Deputado Paes Andrade (PMDB-CE), representante dos parlamentaristas, afirma que o grupo quer o fortalecimento do Poder Legislativo, recolocando-o no centro das decisões nacionais. Na sessão O Povo Pergunta, cidadã quer saber se a nova Constituição está voltada para os pequenos interesses ou para o interesse da maioria. O Deputado Waldir Pugliese (PMDB-PR) responde que tem esperança de que a nova Constituição seja feita em favor da grande maioria do povo brasileiro. Crianças entregam emenda popular ao Presidente da Assembleia Nacional Constituinte, Deputado Ulysses Guimarães (PMDB-SP), pedindo proteção ao menor em situação de risco e o direito ao ensino gratuito a partir dos sete anos de idade. O Deputado Robson Marinho (PMDB-SP) declara que a nova Constituição deve começar pelas crianças. Deficientes físicos entregam emenda popular buscando um tratamento de igualdade e respeito pelos seus direitos. Sessão Extraordinária da Assembleia Nacional Constituinte (ANC) teve como tema a educação. O Deputado Sólon Borges dos Reis (PTB-SP) afirma que as escolas privadas devem ser autofinanciadas. O Deputado Eraldo Tinoco (PFL-BA) considera que algumas instituições sem fins lucrativos devem receber financiamento público.

Diário da Constituinte [gravação de vídeo] : [programa n. 182 A]

O Relator da Assembleia Nacional Constituinte (ANC) Bernardo Cabral (PMDB-AM) irá examinar todas as emendas e redigir novo relatório. O Senador Itamar Franco (PL-MG) percebe uma preocupação exagerada com o número de artigos da Constituição e considera perigoso deixar tudo para a legislação ordinária e legislação complementar. Grande movimento no último dia para a entrega das emendas dos constituintes e das emendas populares. A Deputada Lúcia Braga (PFL-PB) acredita que a sociedade deve continuar mobilizada, sendo necessário que ela acompanhe o trabalho sério que está sendo feito. O Deputado Érico Pegoraro (PFL-RS) almeja um texto constitucional que não abrigue apenas a burguesia, mas principalmente quarenta milhões de brasileiros que não têm um salário mínimo para sobreviver. O Deputado Cunha Bueno (PDS-SP) é a favor do parlamentarismo monárquico, pois os países onde ele existe são estáveis e democráticos. O Deputado Mário Lima (PMDB-BA) relata sobre a emenda popular que trata do monopólio estatal do petróleo, mantendo-o integral e sem os contratos de risco. O Deputado Mário Covas (PMDB-SP) entregou a emenda que pede eleições diretas para presidente da república em 1988 ao Presidente da Assembleia Nacional Constituinte (ANC), Ulysses Guimarães. Em seu discurso o Deputado Mário Covas elogiou o Deputado Ulysses Guimarães, o "Senhor das Diretas". O Deputado Ulysses Guimarães faz um balanço final das emendas populares.