(Table S1) Diatom species richness from the Early Pleistocene to present

The extent to which the spatial distribution of marine planktonic microbes is controlled by local environmental selection or dispersal is poorly understood. Our ability to separate the effects of these two biogeographic controls is limited by the enormous environmental variability both in space and through time. To circumvent this limitation, we analyzed fossil diatom assemblages over the past ~1.5 million years from the world oceans and show that these eukaryotic microbes are not limited by dispersal. The lack of dispersal limitation in marine diatoms suggests that the biodiversity at the microbial level fundamentally differs from that of macroscopic animals and plants for which geographic isolation is a common component of speciation.

ICI 164,384, a pure antagonist of estrogen-stimulated MCF-7 cell proliferation and invasiveness

Estrogen is known to stimulate the proliferation and basement membrane invasiveness of the MCF-7 human breast cancer cell line. We have compared the new steroidal antiestrogen ICI 164,384, the triphenylethylene 4-hydroxytamoxifen (OHT), and the benzothiophene LY 117018, for their effects on the proliferation and invasiveness of the MCF-7 cell line and its antiestrogen-resistant variant LY-2. While all three antiestrogens blocked the proliferative effects of 17β-estradiol on MCF-7 cells, OHT and LY 117018, but not ICI 164,384 stimulated their proliferation in the absence of estrogen. The proliferative effects of OHT and LY 117018 were blocked by ICI 164,384. Basement membrane invasiveness of MCF-7 cells was stimulated by 17β-estradiol and OHT, but not LY 117018 or ICI 164,384. Both ICI 164,384 and Ly 117018 were able to block the invasiveness induced by either 17β-estradiol or OHT. The LY-2 antiestrogen-resistant variant of the MCF-7 cell line showed increased basal proliferation, and responded only slightly to estrogen. ICI 164,384, but not OHT or LY 117018 antagonized the effects of 17β-estradiol, but did not reduce proliferation below control levels. The LY-2 line was not resistant to the antiestrogenic effects of LY 117018 or ICI 164,384 on invasiveness, and was stimulated by LY 117018 for this parameter. Thus, ICI 164,384 is a pure antiestrogen for MCF-7 cell proliferation and invasiveness, and may offer clinical advantage over nonsteroidal antiestrogens which can stimulate these activities in tumor models in vitro.

Sapientia, 1987, Vol. XLII, nº 164 (número completo)

Contenido: Dios en la filosofía (cont.) / Octavio N. Derisi -- El acto constitutivo del conocimiento y de la cognoscibilidad o verdad / Octavio N. Derisi -- Presupuestos necesarios para una recta formulación del concepto de ciencia práctica / Federico Mihura Seeber -- Filosofía tomista, educación y teología en Fray Alberto García Vieyra O.P. 1912-1985 / Alberto Caturelli -- Notas y comentarios -- Bibliografía

Diário da Constituinte [gravação de vídeo] : [programa n. 164]

O Senador Afonso Arinos (PFL-RJ), Presidente da Comissão de Sistematização da Assembleia Nacinal Constituinte (ANC), debate diversos assuntos polêmicos com o Presidente da ANC, Deputado Ulysses Guimarães (PMDB-SP) e lideranças partidárias. Ele é favorável ao adiamento da decisão dos temas polêmicos, para evitar um número exagerado de artigos na nova Constituição. O ator José Dumond pede a população que ocupe seu espaço na discussão da Constituinte. O Deputado Eduardo Moreira (PMDB-SC) defende emenda do Deputado Eduardo Jorge (PT-SP) que beneficia aposentados. No Plenário, o Senador Francisco Rollemberg (PMDB-SE) pede a transferência, para o Estado de Sergipe, de uma grande área pertencente ao Estado da Bahia. O Deputado João Machado Rollemberg (PFL-SE) apoia essa ideia, porque a região não está sendo assistida pelo Estado da Bahia. O Deputado Gil César (PMDB-MG) almeja a negociação da dívida externa, para que o Brasil continue tendo acesso aos capitais externos.

Final Supplemental Environmental Document Pacific herring commercial fishing regulations (Sections 163, 163.1, and 164, Title 14, California Code of Regulations)

(PDF contains 63 pages.)

Cultivation methods for Lemnaceae [Translation from: Wiadomosci Botaniczne 7(2) 153-164, 1963]

Representatives from the family of Lemnaceae (duckweed) make ideal experimental material for research into a succession of phytophysiological processes with regard to growth rate and vegetative reproduction. They are also easy to maintain in sterile cultures. Lemnaceae belong to the higher flowering plants (flowers are rarely produced), however they are distinguished by a much simplified morphological and anatomical structure. As water plants they possess the advantage, that they can be cultivated in synthetic media under laboratory conditions controlled by the application of both a known light intensity and temperature. This paper describes experimental research of growth of Lemnaceae in different conditions. Some of the variables were mineral media, illumination and aeration.