Lógicas de acção na gestão intermédia das escolas : o caso do departamento curricular das expressões

O tema da investigação prende-se com a gestão intermédia das escolas, especificamente, o departamento curricular de expressões (DCEXP). Este estudo analisa as mudanças provocadas pelo novo modelo de estrutura intermédia estabelecido pelo DL nº 75/2008, de 22 de Abril, tendo em conta os vários modelos de agrupamento de escolas vigentes no actual sistema educativo. Procurou-se conhecer a perspectiva de directores, coordenadores de departamento de expressões e professores do mesmo departamento sobre os processos organizacionais e as lógicas de acção desenvolvidas. Para consolidar as múltiplas interrogações e o trajecto final assentar numa reflexão solidamente construída, o corpus teórico envolveu duas grandes temáticas: abordagem da escola como organização e o seu desenvolvimento no sistema educativo português. Em termos metodológicos, optou-se por um estudo qualitativo, com características exploratórias e descritivas. Para a recolha de dados, seleccionámos três agrupamentos de escolas de três concelhos limítrofes ao distrito de Lisboa (um agrupamento vertical, um agrupamento horizontal e um mega agrupamento). Os sujeitos participantes de cada agrupamento foram os directores, os coordenadores do departamento curricular de expressões, um professor do mesmo departamento com muita experiência profissional e um com menos experiência. Realizaram-se doze entrevistas semi-estruturadas, constituídas por um conjunto de questões formuladas a partir dos objectivos e organizadas em temas. Para analisar os dados, utilizámos a técnica de análise de conteúdo. A análise das representações dos diversos grupos de entrevistados permitiu vislumbrar que, apesar da aceitação das mudanças estabelecidas pelos normativos vigentes, as lógicas de acção mantêm-se centradas nas disciplinas de forma fragmentada, dificultando processos colaborativos interdisciplinares. A insatisfação em relação ao actual modelo é consensual em todos os grupos de entrevistados tendo presente a sua complexidade que resulta de aspectos relacionados com a sua dimensão e multidisciplinaridade. No entanto, também vislumbrámos aspectos potenciadores do DCEXP que o valorizam na organização escolar e no processo educativo dos alunos.

Aspiração manual de trombos no enfarte agudo do miocárdio com supradesnivelamento segmento ST: impacto da técnica de aspiração manual de trombos na reperfusão do miocárdio durante a intervenção coronária percutânea primária

Mestrado em Tecnologia de Diagnóstico e Intervenção Cardiovascular. Área de especialização: Intervenção Cardiovascular.

Virtual power players dealing with excessive wind power situations using real time pricing

The increasing importance given by environmental policies to the dissemination and use of wind power has led to its fast and large integration in power systems. In most cases, this integration has been done in an intensive way, causing several impacts and challenges in current and future power systems operation and planning. One of these challenges is dealing with the system conditions in which the available wind power is higher than the system demand. This is one of the possible applications of demand response, which is a very promising resource in the context of competitive environments that integrates even more amounts of distributed energy resources, as well as new players. The methodology proposed aims the maximization of the social welfare in a smart grid operated by a virtual power player that manages the available energy resources. When facing excessive wind power generation availability, real time pricing is applied in order to induce the increase of consumption so that wind curtailment is minimized. The proposed method is especially useful when actual and day-ahead wind forecast differ significantly. The proposed method has been computationally implemented in GAMS optimization tool and its application is illustrated in this paper using a real 937-bus distribution network with 20310 consumers and 548 distributed generators, some of them with must take contracts.

Gil Eannes: le navire-hòpital de la flotte morutière portugaise

Vesalius 2008; XIV: 23-26

Defying Standard Criteria for Digital Replantation: A Case Series

INTRODUCTION: There is much controversy regarding the current indications and contraindications for digital replantation. PRESENTATION OF CASE: Three patients with absolute contraindications for digital replantation according to classical criteria are presented (Case 1: multilevel amputation of the hand and fingers; Case 3: avulsion of the thumb; Case 4: index amputation proximal to the insertion of the flexor digitorum superficialis). In addition a patient with a very distal digital amputation (Case 2), whose indication for replantation is controversial is also presented. In all cases, the patients were replanted and showed good functional and aesthetical results. DISCUSSION: Most authors advocate that the classical indications for replantation have been validated by experience, are predicated on the potential for long-term function, and should be followed in most if not all cases. However, some surgeons have been adopting a more liberal attitude with good results. CONCLUSION: The clinical cases presented in this paper suggest that the standard criteria for digital replantation should not be followed rigidly but instead should be regarded as a general guide.

Curtis's botanical magazine.

v.33=no.1329-1373 (1811)

Bestimmung von Präferenzen bei der Studiengangs- und Studienortwahl aus Sicht von Studierenden mittels Choice-Based Conjointanalyse

Diese Bachelorarbeit gliedert sich in einen theoretischen und einen praktischen Abschnitt. Zunächst werden Studien- und Berufswahlmodelle aus theoretischer Sicht betrachtet. Dabei ist festzuhalten, dass kein Ansatz existiert, der den komplexen Studienwahlprozess vollständig abbildet und erklärt. Jedoch ergänzen sich verschiedene Modelle, sodass alle bedeutenden Einflussfaktoren berücksichtigt sind. Ebenso die Conjointanalyse wird einer theoretischen Betrachtung unterzogen. Als eine Methode der Präferenzmessung wird dieses Analyseverfahren häufig eingesetzt, um die Vorziehenswürdigkeit von Produkten zu ermitteln. Sowohl im Bereich der Neuproduktentwicklung, als auch bei der Marktsegmentierung und der Preisfindung findet die Analyse Verwendung. Sehr charakteristisch für die Methodik ist, dass die Präferenzbeurteilung ganzheitlich für das Produkt erfolgt und nicht direkt einzelne Produkteigenschaften bei der Auskunftsperson abgefragt werden. Besonders relevant für diese Arbeit ist die Choice-Based Conjointanalyse. Die Vorziehenswürdigkeit von Konzepten werden basierend auf Auswahlentscheidungen von Probanden erfasst. Die Beweggründe bei der Studienortwahl aus Sicht der Studierenden an der Hochschule Anhalt werden im praktischen Abschnitt dieser Ausarbeitung mit Hilfe der Choice-Based Conjointanalyse untersucht. Dafür wurde ein Fragebogen entwickelt. Es konnte ermittelt werden, dass sowohl der Ruf der Hochschule, als auch die Heimatnähe und die Höhe des Semesterbeitrages bedeutende Einflussfaktoren bei der Studiengangwahl darstellen. Darüber hinaus werden Motive der Studiengangwahl analysiert. Festzuhalten ist, dass sowohl intrinsische Motive, aber auch extrinsische Motive von hoher Wichtigkeit sind.

Involvement of circulating CEA in liver metastases from colorectal cancers re-examined in a new experimental model.

Both experimental and clinical data show evidence of a correlation between elevated blood levels of carcinoembryonic antigen (CEA) and the development of liver metastases from colorectal carcinomas. However, a cause-effect relationship between these two observations has not been demonstrated. For this reason, we developed a new experimental model to evaluate the possible role of circulating CEA in the facilitation of liver metastases. A CEA-negative subclone from the human colon carcinoma cell line CO115 was transfected either with CEA-cDNA truncated at its 3' end by the deletion of 78 base pairs leading to the synthesis of a secreted form of CEA or with a full-length CEA-cDNA leading to the synthesis of the entire CEA molecule linked to the cell surface by a GPI anchor. Transfectants were selected either for their high CEA secretion (clone CO115-2C2 secreting up to 13 microg CEA per 10(6) cells within 72 h) or for their high CEA membrane expression (clone CO115-5F12 expressing up to 1 x 10(6) CEA molecules per cell). When grafted subcutaneously, CO115-2C2 cells gave rise to circulating CEA levels that were directly related to the tumour volume (from 100 to 1000 ng ml(-1) for tumours ranging from 100 to 1000 mm3), whereas no circulating CEA was detectable in CO115 and CO115-5F12 tumour-bearing mice. Three series of nude mice bearing a subcutaneous xenograft from either clone CO115-2C2 or the CO115-5F12 transfectant, or an untransfected CO115 xenograft, were further challenged for induction of experimental liver metastases by intrasplenic injection of three different CEA-expressing human colorectal carcinoma cell lines (LoVo, LS174T or CO112). The number and size of the liver metastases were shown to be independent of the circulating CEA levels induced by the subcutaneous CEA secreting clone (CO115-2C2), but they were directly related to the metastatic properties of the intrasplenically injected tumour cells.

Loss of connexin40 is associated with decreased endothelium-dependent relaxations and eNOS levels in the mouse aorta.

Upon agonist stimulation, endothelial cells trigger smooth muscle relaxation through the release of relaxing factors such as nitric oxide (NO). Endothelial cells of mouse aorta are interconnected by gap junctions made of connexin40 (Cx40) and connexin37 (Cx37), allowing the exchange of signaling molecules to coordinate their activity. Wild-type (Cx40(+/+)) and hypertensive Cx40-deficient mice (Cx40(-/-)), which also exhibit a marked decrease of Cx37 in the endothelium, were used to investigate the link between the expression of endothelial connexins (Cx40 and Cx37) and endothelial nitric oxide synthase (eNOS) expression and function in the mouse aorta. With the use of isometric tension measurements in aortic rings precontracted with U-46619, a stable thromboxane A(2) mimetic, we first demonstrate that ACh- and ATP-induced endothelium-dependent relaxations solely depend on NO release in both Cx40(+/+) and Cx40(-/-) mice, but are markedly weaker in Cx40(-/-) mice. Consistently, both basal and ACh- or ATP-induced NO production were decreased in the aorta of Cx40(-/-) mice. Altered relaxations and NO release from aorta of Cx40(-/-) mice were associated with lower expression levels of eNOS in the aortic endothelium of Cx40(-/-) mice. Using immunoprecipitation and in situ ligation assay, we further demonstrate that eNOS, Cx40, and Cx37 tightly interact with each other at intercellular junctions in the aortic endothelium of Cx40(+/+) mice, suggesting that the absence of Cx40 in association with altered Cx37 levels in endothelial cells from Cx40(-/-) mice participate to the decreased levels of eNOS. Altogether, our data suggest that the endothelial connexins may participate in the control of eNOS expression levels and function.

Cost of Illness and Contingent Valuation : Controlling for the Motivations of Expressed Preferences in an Attempt to Avoid Double-Counting

This paper addresses the issue of double counting of health impacts in the context of cost of illness valuation. Double counting occurs when estimates are jointly used, which rely on valuation techniques that overlap. As a solution, we propose to limit the scope of each of the valuation method to a specific range of impacts. In order to limit the contingentvaluation method to the exclusive valuation of intangible costs, we propose a three steps approach : (1) leave the respondents free to valuate the consequences which matter to them, (2) elicit respondent's motivations, (3) control for the influence motivations have on elicited values. This procedure was applied in a Swiss contingent-valuation. An econometric treatment was applied in order to limit the scope of the estimates of the contingent valuation method to intangibles,therefore the possibility to a combination of methods with the risk of double-counting and underestimating costs being kept to a minimum.