HIV incidence estimates and HIV/AIDS concurrent diagnosis in Houston/Harris County

The purpose of this dissertation was to estimate HIV incidence among the individuals who had HIV tests performed at the Houston Department of Health and Human Services (HDHHS) public health laboratory, and to examine the prevalence of HIV and AIDS concurrent diagnoses among HIV cases reported between 2000 and 2007 in Houston/Harris County. ^ The first study in this dissertation estimated the cumulative HIV incidence among the individuals testing at Houston public health laboratory using Serologic Testing Algorithms for Recent HIV Seroconversion (STARHS) during the two year study period (June 1, 2005 to May 31, 2007). The HIV incidence was estimated using two independently developed statistical imputation methods, one developed by the Centers for Disease Control and Prevention (CDC), and the other developed by HDHHS. Among the 54,394 persons who tested for HIV during the study period, 942 tested HIV positive (positivity rate=1.7%). Of these HIV positives, 448 (48%) were newly reported to the Houston HIV/AIDS Reporting System (HARS) and 417 of these 448 blood specimens (93%) were available for STARHS testing. The STARHS results showed 139 (33%) out of the 417 specimens were newly infected with HIV. Using both the CDC and HDHHS methods, the estimated cumulative HIV incidences over the two-year study period were similar: 862 per 100,000 persons (95% CI: 655-1,070) by CDC method, and 925 per 100,000 persons (95% CI: 908-943) by HDHHS method. Consistent with the national finding, this study found African Americans, and men who have sex with men (MSM) accounted for most of the new HIV infections among the individuals testing at Houston public health laboratory. Using CDC statistical method, this study also found the highest cumulative HIV incidence (2,176 per 100,000 persons [95%CI: 1,536-2,798]) was among those who tested in the HIV counseling and testing sites, compared to the sexually transmitted disease clinics (1,242 per 100,000 persons [95%CI: 871-1,608]) and city health clinics (215 per 100,000 persons [95%CI: 80-353]. This finding suggested the HIV counseling and testing sites in Houston were successful in reaching high risk populations and testing them early for HIV. In addition, older age groups had higher cumulative HIV incidence, but accounted for smaller proportions of new HIV infections. The incidence in the 30-39 age group (994 per 100,000 persons [95%CI: 625-1,363]) was 1.5 times the incidence in 13-29 age group (645 per 100,000 persons [95%CI: 447-840]); the incidences in 40-49 age group (1,371 per 100,000 persons [95%CI: 765-1,977]) and 50 or above age groups (1,369 per 100,000 persons [95%CI: 318-2,415]) were 2.1 times compared to the youngest 13-29 age group. The increased HIV incidence in older age groups suggested that persons 40 or above were still at risk to contract HIV infections. HIV prevention programs should encourage more people who are age 40 and above to test for HIV. ^ The second study investigated concurrent diagnoses of HIV and AIDS in Houston. Concurrent HIV/AIDS diagnosis is defined as AIDS diagnosis within three months of HIV diagnosis. This study found about one-third of the HIV cases were diagnosed with HIV and AIDS concurrently (within three months) in Houston/Harris County. Using multivariable logistic regression analysis, this study found being male, Hispanic, older, and diagnosed in the private sector of care were positively associated with concurrent HIV and AIDS diagnoses. By contrast, men who had sex with men and also used injection drugs (MSM/IDU) were 0.64 times (95% CI: 0.44-0.93) less likely to have concurrent HIV and AIDS diagnoses. A sensitivity analysis comparing difference durations of elapsed time for concurrent HIV and AIDS diagnosis definitions (1-month, 3-month, and 12-month cut-offs) affected the effect size of the odds ratios, but not the direction. ^ The results of these two studies, one describing characteristics of the individuals who were newly infected with HIV, and the other study describing persons who were diagnosed with HIV and AIDS concurrently, can be used as a reference for HIV prevention program planning in Houston/Harris County. ^

Tuberculosis in Texas correctional facilities between 2005--2009

It has been well documented that inmates incarcerated in prisons and correctional facilities exhibit higher incidence and prevalence of mycobacterium tuberculosis (TB) disease than the general population. This has public health implications because correctional systems may serve as reservoirs for TB disease that can lead to TB outbreaks in the facilities or can be spread to the general public once inmates are released. Although Texas has one of the largest correctional systems in both the US and the world, little is known about TB prevalence and incidence among Texas inmates. The purpose of this study was to elucidate the relationship between TB incidence and incarceration in Texas correctional facilities and investigate differences in various demographic factors. ^ The study used the national TB database from the US Centers for Disease Control and Prevention (CDC) to calculate and compare the overall incidences of TB disease among correctional facility inmates and similar non-inmates in Texas during 2005–2009. Data were also stratified by age, gender, race/ethnicity, birth status, and HIV status and compared between inmates and non-inmates using chi-squared analysis and relative risks with 95% confidence intervals to assess any significant differences. ^ Results suggest that the overall TB incidence among Texas correctional facility inmates per year (88.6 per 100,000) was significantly higher than that of Texas non-inmates (6.3 per 100,000); a 14 fold difference. Relative risk analyses by gender, race/ethnicity, and those with HIV infection found that the TB incidences for all these demographics were significantly and consistently higher in inmates compared to non-inmates. In particular, Hispanic inmates were more likely to develop TB than their non-inmate counterparts by a relative risk of 23.9 (95% CI 19.4–29.4). Likewise, both male and female inmates were more likely to develop TB than non-inmates (RR = 10.2, 95% CI 8.5–12.2; RR = 20.8, 95% CI 12.2–25.3, respectively), although female inmates unconventionally exhibited a higher TB incidence and relative risk than males inmates, which has not been shown. Among those with HIV infections, correctional facility inmates were 2.6 times were likely to develop TB disease than non-inmates (95% CI 1.5–4.4). ^ Inmates in Texas correctional facilities have a higher incidence of TB than non-inmates. Part of this higher risk may be because a large proportion of inmates come from populations already at high risks for TB, such as foreign born immigrants, those infected with HIV, and low SES groups such as many racial/ethnic minorities. Thus, these results may be used as a basis for more controlled and detailed research in the area, and to further characterize incarceration as a risk factor for TB incidence. They may also bring much needed attention about this health disparity to public health officials, legislators, and health administrators to expand and improve TB control in Texas correctional facilities, particularly among inmates released to the community, and reduce the risk of TB transmission to the general population.^

The Relationship of Provincial Economic Level and Child Injury Mortality in Thailand: A Cross-Sectional Analysis in a Middle Income Country

The objective of this cross-sectional study was to examine the relationship of provincial economic development indices with incidences of child injury mortality in Thailand from 1999 - 2001. All injury deaths among children age 1-14 years were included. The independent variables included gross provincial product per capita (GPP/c), poverty and inequality indices, material and social deprivation indices, population in rural/ urban areas, and migration. Due to multicollinearity of such variables, the 76 provinces were categorized by GPP/c quartile, and means of overall injury, drowning, and transport-related mortality rates were compared among quartile groups. Spearman’s rho correlation between GPP/c and injury mortality rates was also performed. Finally, factor analysis was employed to create a set of factors to be treated as uncorrelated variables and stepwise multiple regression was carried out for the effects of the factors on injury mortality rates. A significant direct relationship was observed between GPP/c and overall injury mortality among children age 1-4 years, and 10-14 year-olds of both genders. Drowning was the main cause of this relationship among children age 1-4 years, and transport-related injury was the principle cause among children age 10-14 years. Conversely, provinces with lower GPP/c experienced higher injury mortality rates among school-age children 5-9 years old for both genders, mostly due to drowning. Factor analysis, and multiple regression results confirmed the relationships between economic development and injury mortality rates. These findings revealed that economic development had an adverse impact on injury-related mortality among children 1 to 4 and 10 to14 in Thailand.

Investigation of I -compounds (newly discovered indigenous DNA modifications) by different approaches

I-compounds are newly discovered covalent DNA modifications detected by the $\sp{32}$P-postlabeling assay. They are age-dependent, tissue-specific and sex-different. The origin(s), chemistry and function(s) of I-compounds are unknown. The total level of I-compounds in 8-10 month old rat liver is 1 adduct in 10$\sp7$ nucleotides, which is not neglectable. It is proposed that I-compounds may play a role in spontaneous tumorigenesis and aging.^ In the present project, I-compounds were investigated by several different approaches. (1) Dietary modulation of I-compounds. (2) Comparison of I-compounds with persistent carcinogen DNA adducts and 5-methylcytosine. (3) Strain differences of I-compounds in relation to organ site spontaneous tumorigenesis. (4) Effects of nongenotoxic hepatocarcinogenes on I-compounds.^ It was demonstrated that the formation of I-compounds is diet-related. Rats fed natural ingredient diet exhibited more complex I-spot patterns and much higher levels than rats fed purified diet. Variation of major nutrients (carbohydrate, protein and fat) in the diet, produced quantitative differences in I-compounds of rat liver and kidney DNAs. Physiological level of vitamin E in the diet reduced intensity of one I-spot compared with vitamin E deficient diet. However, extremely high level of vitamin E in the diet gave extra spot and enhanced the intensities of some I-spots.^ In regenerating rat liver, I-compounds levels were reduced, as carcinogen DNA adducts, but not 5-methylcytosine, i.e. a normal DNA modification.^ Animals with higher incidences of spontaneous tumor or degenerative diseases tended to have a lower level of I-compounds.^ Choline devoid diet induced a drastic reduction of I-compound level in rat liver compared with choline supplemented diet. I-compound levels were reduced after multi-doses of carbon tetrachloride (CCl$\sb4$) exposure in rats and single dose exposure in mice. An inverse relationship was observed between I-compound level and DNA replication rate. CCl$\sb4$-related DNA adduct was detected in mice liver and intensities of some I-spots were enhanced 24 h after a single dose exposure.^ The mechanisms and explanations of these observations will be discussed. I-compounds are potentially useful indicators in carcinogenesis studies. ^

Activation of c -Met contributes to growth and metastasis of human colorectal carcinoma

c-Met is the protein tyrosine kinase receptor for hepatocyte growth factor/scatter factor (HGF/SF) and mediates several normal cellular functions including proliferation, survival, and migration. Overexpression of c-Met correlates with progression and metastasis of human colorectal carcinoma (CRC). The goals of this study were to determine if overexpression of c-Met directly contributes to tumorigenicity and liver metastatic potential of colon cancer, and what are the critical pathways regulated by c-Met in this process. The studies used two colon tumor cell lines, KM12SM and KM20, which express high levels of constitutively active c-Met and are highly metastatic in nude mice. To examine the effects of c-Met overexpression, subclones of theses lines with reduced c-Met expression were obtained following transfection with a c-Met specific targeting ribozyme. Reduction of c-Met in KM12SM cells abolished liver metastases when cells were injected intrasplenically in an experimental metastasis assay. However, c-Met downregulation in theses clones was unstable. Three stable KM20 clones with a 25–35% reduction in c-Met protein levels but 60–90% reduction in basal c-Met autophosphorylation and kinase activity were obtained. While HGF increased c-Met kinase activity in the clones with reduced c-Met, the activity was less than that observed in parental or control transfected cells. Correlating with the reduction in c-Met kinase activity, subclones with reduced c-Met expression had significantly reduced in vitro growth rates, soft-agar colony forming abilities, and increased apoptosis. HGF/SF treatment did not affect anchorage-dependent growth or soft-agar colony forming abilities. Further, c-Met downregulation significantly impaired the ability of HGF/SF to induce migration. To examine the effects of reduced c-Met on tumor formation, parental and c-Met reduced KM20 cells were grown subcutaneously and intrahepatically in nude mice. c-Met downregulation delayed, but did not abolish growth at the subcutaneous site. When these cells were injected intrahepatically, both tumor incidences and size were significantly reduced. To further understand the molecular basis of c-Met in promoting tumor growth, the activation of several signaling intermediates that have been implicated in c-Met mediated growth, survival and migration were compared between KM20 parental cells and subclones with reduced c-Met expression levels. The expression and activity (as determined by phosphorylation) of AKT and Erk1/2 were unaltered. In contrast, Src kinase activity, as measured by immune complex kinase assay, was reduced 2–5 fold following c-Met downregulation. As Src has been implicated in growth, survival and migration, Src activation in c-Met overexpressing lines is likely contributing to the tumorigenic and metastatic capabilities of colon tumor cell lines that overexpress c-Met. Collectively, these results suggest that c-Met overexpression plays a causal role in the development of CRC liver metastases, and that c-Src and c-Met inhibitors may be of potential therapeutic benefit for late-stage colon cancer. ^

Tradición Clásica en Iberoamerica

La Tradición Clásica en Iberoamérica presenta la relación de los países sudamericanos con Europa occidental, desde el punto de vista de la vinculación estrictamente cultural. El estudio incluye dieciocho países de habla hispana, uno de habla portuguesa y, en cierto aspecto, Puerto Rico. Se señalan tres etapas culturales que presentan diferentes inidencias de la antigüedad clásica en Iberoamérica. Ellas son: 1. La Conquista, 2. La independenicia y 3. El siglo XX en adelante. Iberoamérica constituye el mito de la utopía descubierta por Europa y retiene en su esencia vital el sentimiento utópico por la búsqueda constante de la unidad en la pluralidad.

Tradición Clásica en Iberoamerica

La Tradición Clásica en Iberoamérica presenta la relación de los países sudamericanos con Europa occidental, desde el punto de vista de la vinculación estrictamente cultural. El estudio incluye dieciocho países de habla hispana, uno de habla portuguesa y, en cierto aspecto, Puerto Rico. Se señalan tres etapas culturales que presentan diferentes inidencias de la antigüedad clásica en Iberoamérica. Ellas son: 1. La Conquista, 2. La independenicia y 3. El siglo XX en adelante. Iberoamérica constituye el mito de la utopía descubierta por Europa y retiene en su esencia vital el sentimiento utópico por la búsqueda constante de la unidad en la pluralidad.

Tradición Clásica en Iberoamerica

La Tradición Clásica en Iberoamérica presenta la relación de los países sudamericanos con Europa occidental, desde el punto de vista de la vinculación estrictamente cultural. El estudio incluye dieciocho países de habla hispana, uno de habla portuguesa y, en cierto aspecto, Puerto Rico. Se señalan tres etapas culturales que presentan diferentes inidencias de la antigüedad clásica en Iberoamérica. Ellas son: 1. La Conquista, 2. La independenicia y 3. El siglo XX en adelante. Iberoamérica constituye el mito de la utopía descubierta por Europa y retiene en su esencia vital el sentimiento utópico por la búsqueda constante de la unidad en la pluralidad.

Diurnal and seasonal measurements of seawater chemistry, temperature and PAR in Hurricane Hole, U.S. Virgin Islands - 2010-2012

Risk analyses indicate that more than 90% of the world's reefs will be threatened by climate change and local anthropogenic impacts by the year 2030 under "business-as-usual" climate scenarios. Increasing temperatures and solar radiation cause coral bleaching that has resulted in extensive coral mortality. Increasing carbon dioxide reduces seawater pH, slows coral growth, and may cause loss of reef structure. Management strategies include establishment of marine protected areas with environmental conditions that promote reef resiliency. However, few resilient reefs have been identified, and resiliency factors are poorly defined. Here we characterize the first natural, non-reef coral refuge from thermal stress and ocean acidification and identify resiliency factors for mangrove-coral habitats. We measured diurnal and seasonal variations in temperature, salinity, photosynthetically active radiation (PAR), and seawater chemistry; characterized substrate parameters; and examined water circulation patterns in mangrove communities where scleractinian corals are growing attached to and under mangrove prop roots in Hurricane Hole, St. John, US Virgin Islands. Additionally, we inventoried the coral species and quantified incidences of coral bleaching, mortality, and recovery for two major reef-building corals, Colpophyllia natans and Diploria labyrinthiformis, growing in mangrove-shaded and exposed (unshaded) areas. Over 30 species of scleractinian corals were growing in association with mangroves. Corals were thriving in low-light (more than 70% attenuation of incident PAR) from mangrove shading and at higher temperatures than nearby reef tract corals. A higher percentage of C. natans colonies were living shaded by mangroves, and no shaded colonies were bleached. Fewer D. labyrinthiformis colonies were shaded by mangroves, however more unshaded colonies were bleached. A combination of substrate and habitat heterogeneity, proximity of different habitat types, hydrographic conditions, and biological influences on seawater chemistry generate chemical conditions that buffer against ocean acidification. This previously undocumented refuge for corals provides evidence for adaptation of coastal organisms and ecosystem transition due to recent climate change. Identifying and protecting other natural, non-reef coral refuges is critical for sustaining corals and other reef species into the future.

Gender-preferential intergenerational patterns in primary education attainment : a quantitative analysis of a case of rural Mindanao, the Philippines

The Philippines has achieved a relatively high standard of education. Previous researches, most of which deal with Luzon Island, have indicated that rural poverty alleviation began partly due to the increased investment in education. However, the suburban areas beyond Luzon Island have rarely been studied. This study examines a case from rural Mindanao, and investigates the determinants and factors associated with children's education, with a special focus on delays in schooling, which may be a cause of dropout and holdover incidences, as well as exploring gender-specific differential patterns. The result shows that after controlling other socioeconomic attributes, (1) delays in schooling, as well as years completed, are more favorable for girls than boys; (2) the level of maternal education is equally associated with the child(ren)’s education level regardless of their gender; and (3) paternal education is preferentially and favorably influential to the same-gender child(ren), i.e., son(s). To reduce the boy-unfriendly gender bias in primary education, this study suggests two future tasks, i.e., providing boy-specific interventions to enhance the magnitude of the father-son educational virtuous circle, and comparing the magnitude of gender-equal maternal education influence and boy-preferential paternal education influence to specify which effect is larger.

Combination of optical and on-destructivemechanicaltechniques for the measurement of maturity in peach

Increasing consumer dissatisfaction related with lack of ripeness in peach has been repeatedly reported since 1990 to the present day. There is thus, a great interest in improving the assessment of peach maturity, currently based on Magness Taylor firmness (destructive, highly variable, and time consuming) and colour (not reliable for highly coloured varieties). The present research studies as an alternative several non-destructive (ND) measurements, based on multispectral imaging, visible spectra, and low mass impact response. Their relationship with maturity, as well as the potential of their combination was studied. As a result, two rather independent (R2 = 0.3) groups of non-destructive measurements, chlorophyll related optical indexes and low mass impact (LMI) measurements, were identified. Optical measurements showed the best behaviour for assessing maturity at harvest, while LMI measurements reflected handling incidences, showing a promising potential to be used to control transport and postharvest handling.

Estimación de ahorro por inspección del regulador del mercado energético a las instalaciones de energías renovables

La Administración General del Estado, a través de la Comisión Nacional de la Energía, y en colaboración con los órganos competentes de las Comunidades Autónomas correspondientes, realiza inspecciones periódicas y aleatorias cada año, sobre las instalaciones de generación eléctrica, siguiendo los criterios de elección e indicaciones que la Secretaria General de la Energía del Ministerio de Industria, Turismo y Comercio imponga en cada caso. En este proyecto se analizan las distintas incidencias de las distintas tecnologías estudiadas, así como las consecuencias jurídicas y económicas. También se ofrecen las distintas propuestas de sanción como consecuencia de estas incidencias. El objeto del presente proyecto es el estudio de la reducción de costes al estado si el organismo competente (Comisión Nacional de Energía) liquidase a las diferentes instalaciones en función de las irregularidades detectadas como consecuencia de las inspecciones realizadas durante el plan 2011/2012, así como una estimación de dicho ahorro al extrapolar dichos resultados al total de instalaciones ABSTRACT The Central Government, through the National Energy Commission, in cooperation with the competent bodies of the Autonomous Communities concerned, realizes periodic and random inspections every year on electricity generation facilities, following the criteria of choice and indications that the General Secretary of Energy from the Ministry of Industry, Tourism and Commerce impose in each case. This project analyses the different incidences of the different technologies studied as well as the legal and economic consequences. It is also offered different proposals of sanction as a result of these incidents. The purpose of this project is to study the reduction of costs to the state if the competent agency (CNE) decided to close the different facilities depending on the irregularities as a result of inspections conducted during the plan 2011/2012 and as an estimate of the savings to extrapolate these results to all the facilities.

Human Factor in Resilience Systems

This paper shows the importance of a holistic comprehension of the Earth as a living planet, where man inhabits and is exposed to environmental incidences of different nature. The aim of the paper here summarized is a reflection on all these concepts and scientific considerations related to the important role of men in the handling of natural hazards. Our Planet is an unstable and dynamical system highly sensitive to initial conditions, as proposed by Chaos theory (González-Miranda 2004); it is a complex organic whole, which responds to minimal variations which can affect several natural phenomena such as plate tectonics, solar flares, fluid turbulences, landscape formation, forest fires, growth and migration of populations and biological evolution. This is known as the “butterfly effect” (Lorenz 1972), which means that a small change of the system causes a chain of events leading to large-scale unpredictable consequences. The aim of this work is dwelling on the importance of the knowledge of these natural and catastrophic geological, biological and human systems so much sensible to equilibrium conditions, to prevent, avoid and mend their effects, and to face them in a resilient way

Novatests : metodología y herramienta software de apoyo para los ingenieros de prueba junior

La Ingeniería de Pruebas está especializada en la verificación y validación del Software,y formalmente se define como: “Proceso de desarrollo que emplea métodos rigurosos para evaluar la corrección y calidad del producto a lo largo de todo su ciclo de vida” [3]. Este proceso comprende un conjunto de métodos, procedimientos y técnicas formalmente definidas las cuales, usadas de forma sistemática, facilitan la identificación de la mayor cantidad de errores y fallos posibles de un software. Un software que pase un proceso riguroso de pruebas es un producto de calidad que seguramente facilitará la labor del Ingeniero de Software en la corrección de futuras incidencias, algunas de ellas generadas tras la implantación en el entorno real. Este proceso constituye un área de la Ingeniería del Software y una especialidad por tanto, de la misma. De forma simple, la consecución de una correcta Verificación y Validación del Software requiere de algunas actividades imprescindibles como: - Realizar un plan de pruebas del proyecto. - Actualizar dicho plan y corregirlo en caso necesario. - Revisar los documentos de análisis de requisitos. - Ejecutar las pruebas en las diferentes fases del desarrollo del proyecto. - Documentar el diseño y la ejecución de las pruebas. - Generar documentos con los resultados y anomalías de las pruebas ya ejecutadas. Actualmente, la Ingeniería de Pruebas no es muy reconocida como área de trabajo independiente sino más bien, un área inmersa dentro de la Ingeniería de Software. En el entorno laboral existe el perfil de Ingeniero de Pruebas, sin embargo pocos ingenieros de software tienen claro querer ser Ingenieros de Pruebas (probadores o testers) debido a que nunca han tenido la oportunidad de enfrentarse a actividades prácticas reales dentro de los centros de estudios universitarios donde cursan la carrera. Al ser un área de inherente ejercicio profesional, la parte correspondiente de la Ingeniería de Pruebas suele enfocarse desde un punto de vista teórico más que práctico. Hay muchas herramientas para la creación de pruebas y de ayuda para los ingenieros de pruebas, pero la mayoría son de pago o hechas a medida para grandes empresas que necesitan dicho software. Normalmente la gente conoce lo que es la Ingeniería de Pruebas únicamente cuando se empieza a adquirir experiencia en dicha área en el ejercicio profesional dentro de una empresa. Con lo cual, el acercamiento durante la carrera no necesariamente le ha ofrecido al profesional en Ingeniería, la oportunidad de trabajar en esta rama de la Ingeniería del Software y en algunos casos, NOVATests: Metodología y herramienta software de apoyo para los Ingenieros de Prueba Junior 4 los recién egresados comienzan su vida profesional con algún desconocimiento en este sentido. Es por el conjunto de estas razones, que mi intención en este proyecto es proponer una metodología y una herramienta software de apoyo a dicha metodología, para que los estudiantes de carreras de Ingeniería Software y afines, e ingenieros recién egresados con poca experiencia o ninguna en esta área (Ingenieros de Pruebas Junior), puedan poner en práctica las actividades de la Ingeniería de Pruebas dentro de un entorno lo más cercano posible al ejercicio de la labor profesional. De esta forma, podrían desarrollar las tareas propias de dicha área de una manera fácil e intuitiva, favoreciendo un mayor conocimiento y experiencia de la misma. ABSTRACT The software engineering is specialized in the verification and validation of Software and it is formally defined as: “Development process which by strict methods evaluates and corrects the quality of the product along its lifecycle”. This process contains a number of methods, procedures and techniques formally defined which used systematically make easier the identification of the highest quantity of error and failures within a Software. A software going through this rigorous process of tests will become a quality product that will help the software engineer`s work while correcting incidences. Some of them probably generated after the deployment in a real environment. This process belongs to the Software engineering and therefore it is a specialization itself. Simplifying, the correct verification and validation of a software requires some essential activities such as: -Create a Test Plan of the project - Update this Test Plan and correct if necessary - Check Requirement’s specification documents -Execute the different tests among all the phases of the project - Create the pertinent documentation about design and execution of these tests. - Generate the result documents and all the possible incidences the tests could contain. Currently, the Test engineering is not recognized as a work area but an area immerse within the Software engineering. The professional environment includes the role of Test engineer, but only a few software engineers have clear to become Test engineers (testers) because they have never had the chance to face this activities within the university study centers where they take study of this degree. Since there are little professional environments, this area is focused from a theoretical way instead of a more practical vision. There are plenty of tools helping the Test engineer, but most of them are paid tools or bespoke tools for big companies in need of this software. Usually people know what test engineering is by starting working on it and not before, when people start acquiring experience in this field within a company. Therefore, the degree studied have not approach this field of the Software engineering before and in some cases the graduated students start working without any knowledge in this area. Because of this reasons explained, it is my intention to propose this Project: a methodology and a software tool supporting this methodology so the students of software engineering and similar ones but also graduated students with little experience in this area (Junior Test Engineers), can afford practice in this field and get used to the activities related with the test engineering. Because of this they will be able to carry out the proper tasks of this area easier, enforcing higher and better knowledge and experience of it.

The Benefits of Sampling Sports During Childhood

Sampling may promote prolonged engagement in sport by limiting physical injuries (Fraser-Thomas et al., 2005). Overtraining injuries are a concern for young athletes who specialize in one sport and engage in high volumes of deliberate practice (Hollander, Meyers, & Leunes, 1995; Law, Côté, & Ericsson, 2007). For instance, young gymnasts who practice for over 16 hours a week have been shown to have higher incidences of back injuries (Goldstein, Berger, Windier, & Jackson, 1991). A sampling approach in child-controlled play (e.g. deliberate play) rather than highly adult-controlled practice (e.g. deliberate practice) has been proposed as a strategy to limit overuse and other sport-related injuries (Micheli, Glassman, & Klein, 2000). In summary, sampling may protect against sport attrition by limiting sport related injuries and allowing children to have early experiences in sport that are enjoyable. Psychosocial Benefits of Sampling Only a small percentage of children who participate in school sports ever become elite athletes. Therefore, the psychosocial outcomes of sport participation are particularly important to consider. Recent studies with youth between the ages of 11 to 17 have found that those who are involved in a variety of extracurricular activities (e.g. sports, volunteer, arts) score more favourably on outcome measures such as Grade Point Average (GPA; Fredricks & Eccles, 2006a) and positive peer relationships (Fredricks & Eccles, 2006b) than youth who participate in fewer activities. These patterns are thought to exist due to each extracurricular activity bringing its own distinct pattern of socialization experiences that reinforce certain behaviours and/or teach various skills (Fredricks & Eccles, 2006b; Rose-Krasnor, Bussen, Willoughby, & Chambers, 2006). This contention is corroborated by studies of children and youths' experiences in extracurricular activities indicating that youth have unique experiences in each activity that contribute to their development (Hansen, Larson, & Dworkin, 2003; Larson, Hansen, & Moneta, 2006). This has led Wilkes and Côté (2007) to propose that children who sample different activities (through their own choice or by virtue of parental direction), have a greater chance of developing the following five developmental outcomes compared to children who specialize in one activity: 1) life skills, 2) prosocial behaviour, 3) healthy identity, 4) diverse peer groups and 5) social capital.