Multiprobabilistic prediction in early medical diagnoses

This paper describes the methodology of providing multiprobability predictions for proteomic mass spectrometry data. The methodology is based on a newly developed machine learning framework called Venn machines. Is allows to output a valid probability interval. The methodology is designed for mass spectrometry data. For demonstrative purposes, we applied this methodology to MALDI-TOF data sets in order to predict the diagnosis of heart disease and early diagnoses of ovarian cancer and breast cancer. The experiments showed that probability intervals are narrow, that is, the output of the multiprobability predictor is similar to a single probability distribution. In addition, probability intervals produced for heart disease and ovarian cancer data were more accurate than the output of corresponding probability predictor. When Venn machines were forced to make point predictions, the accuracy of such predictions is for the most data better than the accuracy of the underlying algorithm that outputs single probability distribution of a label. Application of this methodology to MALDI-TOF data sets empirically demonstrates the validity. The accuracy of the proposed method on ovarian cancer data rises from 66.7 % 11 months in advance of the moment of diagnosis to up to 90.2 % at the moment of diagnosis. The same approach has been applied to heart disease data without time dependency, although the achieved accuracy was not as high (up to 69.9 %). The methodology allowed us to confirm mass spectrometry peaks previously identified as carrying statistically significant information for discrimination between controls and cases.

Improving pedagogy in the middle years

There has been considerable emphasis over the last decade on effective teaching and learning in the middle years of schooling, associated with the particular responses to schooling of adolescent students in a period of their lives when issues of identity, commitment, and independence are central to their experience and concern. Extensive research and development has generated considerable reform in Years 5 to 9. Improved understandings of students' different learning styles and needs has led to more diverse and strategic selection of teaching methods. However, there is still considerable scope for improving the quality of contemporary approaches to the education and development of adolescents. A number of major research projects have been conducted by the Victorian Department of Education and Training (DE&T) middle years strategy team since 1998, including the Middle Years Research and Development (MYRAD) project, the Middle Years Literacy, and Middle Years Numeracy Research projects. Currently, the focus has shifted to a more explicit framing of a Middle Years pedagogical framework. The Middle Years Pedagogy Research and Development (MYPRAD) project has developed an explicit pedagogical framework that is grounded in research findings from previous projects and from the literature more generally.

The infant feeding activity and nutrition trial (INFANT) an early intervention to prevent childhood obesity : cluster-randomised controlled trial

Background : Multiple factors combine to support a compelling case for interventions that target the development of obesity-promoting behaviours (poor diet, low physical activity and high sedentary behaviour) from their inception. These factors include the rapidly increasing prevalence of fatness throughout childhood, the instigation of obesity-promoting behaviours in infancy, and the tracking of these behaviours from childhood through to adolescence and adulthood. The Infant Feeding Activity and Nutrition Trial (INFANT) aims to determine the effectiveness of an early childhood obesity prevention intervention delivered to first-time parents. The intervention, conducted with parents over the infant's first 18 months of life, will use existing social networks (first-time parent's groups) and an anticipatory guidance framework focusing on parenting skills which support the development of positive diet and physical activity behaviours, and reduced sedentary behaviours in infancy.

Methods/Design : This cluster-randomised controlled trial, with first-time parent groups as the unit of randomisation, will be conducted with a sample of 600 first-time parents and their newborn children who attend the first-time parents' group at Maternal and Child Health Centres. Using a two-stage sampling process, local government areas in Victoria, Australia will be randomly selected at the first stage. At the second stage, a proportional sample of first-time parent groups within selected local government areas will be randomly selected and invited to participate. Informed consent will be obtained and groups will then be randomly allocated to the intervention or control group.

Discussion : The early years hold promise as a time in which obesity prevention may be most effective. To our knowledge this will be the first randomised trial internationally to demonstrate whether an early health promotion program delivered to first-time parents in their existing social groups promotes healthy eating, physical activity and reduced sedentary behaviours. If proven to be effective, INFANT may protect children from the development of obesity and its associated social and economic costs.

What's the difference and where is the evidence? Investigating student teachers learning about literacy in a school based vs university based experience

This paper is in response to increasing national and international interest in the role of university teacher education programs in preparing pre-service  teachers in the area of early years literacy. The most effective manner to  facilitate this learning in teacher education is however not known and much debate exists about the merits of university-based versus school-based  approaches. It is within this context that the authors of this paper conducted a study that investigated student teachers learning about literacy through two different approaches both with distinctive design features. The first approach offered student teachers a school based experience, adopting a two hour micro-teaching model in a preparatory classroom; the other, a mainstream university based approach where students attended a tutorial for two hours. These two approaches were then compared for factors that student teachers articulated through a written survey. In analysing the data, two main findings emerged; firstly from the student teachers’ perspective, choice of approach resulted in improved learning and secondly, from the researchers’ perspective that student teachers placed in the school based approach emerged with a deeper understanding of the complexity of literacy teaching in general.

Understanding and developing structure - its importance for mathematics learning

This issue comes at a time when mathematics education research is becoming more intently focused on the development of "structure" as salient to generalised mathematics learning. Not surprisingly the attention on structure creates particular synergies with the increasingly rich field of research on algebraic thinking and arithmetic processes, particularly in the early years. In many ways, this special issue is concerned with describing the process of "structuring" that enables abstraction and generalisation. A recent MERJ special issue, Abstraction in Mathematics Education (Mitchelmore & White, 2007), illustrated theories of abstraction aligning these to notions of underlying structure. The importance of structure in the transition from school to university was also highlighted by Godfrey and Thomas (2008), and Novotna and Hoch (2008) in the previous special issue of MERJ (Thomas, 2008). In this special issue we present six papers that provide evidence of developing structure as critical for all learners of mathematics throughout schooling.

Literacy in early childhood and primary education : issues, challenges and solutions

Literacy in Early Childhood and Primary Education provides a comprehensive introduction to literacy teaching and learning. The book explores the continuum of literacy learning and children's transitions from early childhood settings to junior primary classrooms and then to senior primary and beyond. Reader-friendly and accessible, this book equips pre-service teachers with the theoretical underpinnings and practical strategies to teach literacy. It places the 'reading wars' firmly in the past as it examines contemporary research and practices. The book covers important topics such as assessment, multiliteracies, reading difficulties and diverse classrooms. Each chapter includes learning objectives, reflective questions and definitions of key terms to engage and assist readers. Written by an expert author team and featuring real-world examples from literacy teachers and learners, the book will help pre-service teachers feel confident teaching literacy to diverse age groups and abilities.

How do early childhood teachers understand and support the needs of young English language Learners

In Australia, over one third of all children in Early Childhood programs speak a first language other than English. Despite considerable work into teachers' beliefs on cultural diversity, attention to aspects of second language acquisition in the Early Years has been limited within the Early Childhood field. This paper reports on a small study investigating how four early childhood educators understand theory of Second Language Acquisition (SLA) and bilingualism, and how they cater for language-minority students in their programs. The findings revealed a complex interplay between the way participants interpret and support the needs of these children, their experience in the field, and professional education. The teachers in the study reveal various perspectives on how SLA and bilingualism manifest during the early years, and how they affect the learning of children with a Language Background other than English (LBOTE). The teachers also seemed to rely on experiential and intuitive approaches in planning and teaching English Language Learners (ELLs). This study brings new perspectives to understanding the nature of teachers' beliefs and practice regarding English language learners.

Becoming numerate with information and communications technologies in the twenty-first century

This article draws on data from a three-year Australian Research Council-funded study that examined the ways in which young children become numerate in the twenty-first century. We were interested in the authentic problem-solving contexts that we believe are required to create meaningful learning. This being so, our basic tenet was that such experiences should involve the use of information and communications technologies (ICT) where relevant, but not in tokenistic ways. This article highlights learning conditions in which young children can become numerate in contemporary times. We consider ‘academic’ or ‘school-based’ mathematical tasks in the context of a Mathematical Tasks Continuum. This continuum was conceptualised to enable focused and detailed thinking about the scope and range of mathematical tasks that young children are able to engage within contemporary school contexts. The data from this study show that most of the tasks the children experienced in early years mathematics classes were unidimensional in their make up. That is, they focus on the acquisition of specific skills and then they are practiced in disembedded contexts. We suggest that the framework created in the form of the Mathematical Tasks Continuum can facilitate teachers thinking about the possible ways in which they could extend children’s academic work in primary school mathematics, so that the process of becoming numerate becomes more easily related to authentic activities that they are likely to experience in everyday life.

Communication keys: understanding the importance of the early childhood teacher's role in children's language and literacy development within a holistic, integrative approach to child development

Early childhood is a critical period in children’s lives during which experiences and the quality of the interactions lay the foundation for their subsequent learning and behavior, impacting upon the their lives. In response to Early Years research that identifies the positive impact of quality early years education upon children’s future learning, governments worldwide are implementing changes in policy, processes, professional learning and practice and are pouring funds into early childhood education. A range of approaches and multiple strategies are being adopted in an effort to improve children’s health, education and overall well-being, including the holistic and integrative approach such as that undertaken in Indonesia. This paper argues that high quality Early Childhood teachers play an important role within these approaches and this is discussed in light of the research - policy - praxis nexus, with language and literacy development as a focus area.

Teacher knowledge, child interest and parent expectation: Factors influencing multicultural programs in an early childhood setting

© 2015, Early Childhood Australia Inc. All rights reserved. MULTICULTURAL CURRICULA/PROGRAMS assume an important role within a cultural approach to learning and teaching in early childhood education in New Zealand. Te Whariki, the national early childhood curriculum framework of New Zealand, is an emancipatory and socially constructive document that emphasises equity, social justice and the important position of culture in children's learning and development. In practice this means developing early childhood programs that are sensitive and responsive to the needs and interests of children and families of minority cultures. Drawing on a critical social constructivist framework, this study of one early childhood centre in New Zealand identifies the features of its multicultural curriculum. The paper argues that a devotion to supporting children of minority cultures has persisted in the curriculum, but there is a reliance on mainstream pedagogy focused on children's learning within the centre environment and teachers' subjective knowledge about children's needs.

Ensinar-aprender frações em um curso de formação continuada para professores dos anos iniciais do ensino fundamental: conhecimentos e dificuldades evidenciadas

Este estudo apresenta os dados de uma pesquisa realizada na Universidade Federal do Pará - UFPA, no ano de 2009, em uma turma do Curso de Especialização em Educação em Ciências e Matemáticas para as Séries Iniciais. Durante o período em que se estudou o tema frações, nesse curso de formação continuada, foram investigados os conhecimentos e dificuldades que emergem no fazer ensinar-aprender das professoras que ensinam matemática nos anos iniciais do ensino fundamental. A fundamentação teórica usada para dar suporte a este estudo está apoiada em trabalhos dos autores: Brousseau (2009, 2008, 1996), D’Amore (2007), Pais (2006, 2005), Almouloud (2007), Igliori (2008), Bittencourt (1998). A pesquisa é qualitativa na modalidade descritiva. De uma turma composta de 29 (vinte e nove) professoras que frequentavam o curso de formação, 5 (cinco) foram selecionadas, dentre as que possuíam maior tempo de experiência em sala de aula, para serem os sujeitos investigados na pesquisa. Outras 10 (dez) professoras estão citadas, por terem dado valiosas contribuições para fundamentar as análises. Os instrumentos de investigação usados foram o caderno de campo, questionário, teste e registro produzido pelas professoras pesquisadas. Estes dados foram organizados e apresentados em forma de episódios. Os resultados apontam conhecimentos e dificuldades no fazer ensinar-aprender das professoras em relação ao tema frações. Algumas dificuldades identificadas: 1) fazer comparações entre frações; 2) fazer a representação esquemática de frações. O conhecimento identificado: 1) a construção de equação linear como resultado da leitura e interpretação de problemas com aplicação de frações; 2) a resolução algébrica de problemas envolvendo frações. Entretanto, essas professoras, conscientes de possuírem tais dificuldades, mostraram-se motivadas a superá-las. Essa motivação ficou evidenciada pelo comprometimento que apresentaram ao desenvolver as tarefas que foram propostas no referido curso.

o ensino de leitura na escola: um olhar sobre as concepções de professores do 1º ciclo do ensino fundamental de uma escola municipal de Bauru - SP

This research is being read, thus rendering text on the pole of understanding, as a practice effective dialogue and therefore responsive through which the reader, author, text and context interact. To this end, the reader must turn their knowledge systems and relate them to the linguistic materiality. Thus, aimed to investigate whether the teaching of reading in the early years of elementary school literacy builds skills related to this cultural practice and its relationship to the conceptions of classroom teachers of reading, as well as the teaching and learning methodologies practiced in class classroom. Therefore, I base this research on the theoretical basis of linguistic studies and expository sociointeractionist redefine that, among other things, the concepts of language, genre and text. As for the methodological framework, this study followed the methodology of literature research and fieldwork. The fieldwork took place from the perspective of observing the pedagogical practice of teaching reading, in order to investigate how the educational activities are conducted in a reading room for the third year of elementary school, part of the municipal education Bauru- SP. Were used as instruments of data collection the questionnaire given to school teachers and the school studied the direct observation of teaching practice of one of these professionals. The results of data analysis indicate that the teachers surveyed know key content for teaching reading, as well as renovations of the theoretical and methodological studies of reading, with the consequence that the practices of reading done in the classroom limit the role of student as a reader and does not guarantee the formation of the reader

Práticas dialógicas em sala de aula: condição fundante do sujeito letrado

This research intend to situate the process of literacy as a practice interlocutive acquisition of written language, through which students interact with each other and the teacher, and through these interactions are constituted as a subject of dialogue and history. So he had as an aim to investigate through the key concepts of dialogism Bakhtin and discourse analysis, the possibilities of teaching and learning of reading and writing, using language in use, showing the dialogical practices in order to demonstrate that the verbal interactions that result from the actual discursive situations, actually originated in the classroom, from working with the genre can guide the teaching of reading and writing and its social use. Therefore, I base this research on the methodological framework of literature and field. This takes place in view of observed teaching practice related to the early years of literacy and, therefore, to investigate such activities are carried out that reading and writing during the teaching of mother tongue, as are utilized practices of orality and literacy in room classroom and, even if the teacher makes use of this type of language for the acquisition of written language. The results of analysis of data collected by the instruments used, namely, questionnaires, systematic observation and textual production of the students, point to the fact that the literacy teaching practices, classroom researched are far from forming a student literate because the fact of the teachers surveyed knew not the key content for teaching the language, means that they will lead to literacy, from the point of view of language as a monologic process.

Interfaces da construção da prática docente no ensino de ciências naturais nos anos iniciais da escola pública municipal de Manaus - AM

Pós-graduação em Educação - FCT