958 resultados para chitosan derivative


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Using the operator formalism, we obtain the bosonic representation for the free fermion field satisfying an equation of motion with higher-order derivatives. Then, we consider the operator solution of a generalized Schwinger model with higher-derivative coupling. Since the increasing of the derivative order implies the introduction of an equivalent number of extra fermionic degrees of freedom, the mass acquired by the gauge field is bigger than the one for the standard two-dimensional QED. An analysis of the problem from the functional integration point of view corroborates the findings of canonical quantization, and corrects certain results previously announced in the literature on the basis of Fujikawa's technique.

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Isoniazid was encapsulated into microspheres of alginate-chitosan by means of a complex coacervation method in an emulsion system. Since the encapsulation of isoniazid tends to be limited by its hydrophilic characteristics, this study proposes its microencapsulation by adsorption. The particles were prepared in three steps: (1) preparation of a W/O emulsion; (2) phase separation; and (3) adsorption of the drug. The isolated particles were placed in a solution of the drug under stirring to allow adsorption. The morphology and particle size were analysed by scanning electron microscopy (SEM). The isoniazid content was determined by extraction in 1 m phosphate buffer pH 7.5 under stirring for 4 h. Finally, the samples were filtered and analysed in an UV/VIS spectrophotometer at 260 nm. In vitro release tests were carried out in 0.05 m phosphate buffer pH 7.5. The results showed that microspheres of alginate-chitosan obtained were of spherical shape. The emulsion used for microparticle formation allows the preparation of particles with a narrow size distribution. The adsorption observed is probably of chemical nature, i.e. there is an ionic interaction between the drug and the surface of the particles.

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The nonminimal pure spinor formalism for the superstring is used to prove two new multiloop theorems which are related to recent higher-derivative R-4 conjectures of Green, Russo, and Vanhove. The first theorem states that when 0 < n < 12, partial derivative R-n(4) terms in the Type II effective action do not receive perturbative contributions above n/2 loops. The second theorem states that when n <= 8, perturbative contributions to partial derivative R-n(4) terms in the IIA and IIB effective actions coincide. As shown by Green, Russo, and Vanhove, these results suggest that d=4 N=8 supergravity is ultraviolet finite up to eight loops.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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In some practical problems, for instance in the control systems for the suppression of vibration in mechanical systems, the state-derivative signals are easier to obtain than the state signals. New necessary and sufficient linear matrix inequalities (LMI) conditions for the design of state-derivative feedback for multi-input (MI) linear systems are proposed. For multi-input/multi-output (MIMO) linear time-invariant or time-varying plants, with or without uncertainties in their parameters, the proposed methods can include in the LMI-based control designs the specifications of the decay rate, bounds on the output peak, and bounds on the state-derivative feedback matrix K. These design procedures allow new specifications and also, they consider a broader class of plants than the related results available in the literature. The LMIs, when feasible, can be efficiently solved using convex programming techniques. Practical applications illustrate the efficiency of the proposed methods.

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The structure of 5,7,9,10-tetramethoxy-3-methyl-1 H-naphtho[2,3-c]pyran-1-one, C18H18O6, a derivative of a natural isocoumarin isolated from Paepalanthus bromelioides, was determined by X-ray analysis, which unequivocally confirmed the previously assigned structure. Small deviations from the standard angles, resulting from steric hindrance between the methoxyl and carbonyl groups, were observed.

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One of the overall goals of industries is to use packages that do not cause environmental problems at disposal time, but that have the same properties as the conventional ones. The goal of this study is to synthesize edible films based on hydroxypropyl methylcellulose (HPMC) with guava puree and chitosan (CS) nanoparticles. This was divided into two stages, the first is the synthesis of chitosan nanoparticles and the second is the production of the films. For the nanoparticles, average size and zeta potential measurements were performed. The characterizations of mechanical and thermal properties, solubility and water vapor permeability tests were conducted in the films. It was observed that when the nanoparticles were added to HPMC and guava puree films, they improved their mechanical and thermal properties, as well as decreased the films solubility and permeability. The potential application of the films prepared would be in edible films with flavor and odor to extend the shelf life of products.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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4-Methylpyrimidine-2-thione reacts with methylmercury hydroxide to give the thiolate derivative HgMe(SC4H2N2Me-2), the X-ray structure of which reveals pairs of molecules with a mercury-mercury distance of 3.10 Å.

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We present a higher derivative gauge theory in (2 + 1) dimensions which can have its parameters suitably tuned in order to become a consistent quantum field theory, in the sense that both tachyons and ghosts are absent from the particle spectrum of the theory.