288 resultados para Wener Jaeger
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Thesis (doctoral)--Universitat zu Konigsberg i Pr., 1903.
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Thesis (doctoral)--Albertus-Universitat zu Konigsberg i. Pr., 1900.
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Thesis (doctoral)--Albertus-Universitat zu Konigsberg i. Pr., 1903.
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Beginning with 1907, each number includes "Literaturbericht."
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Thesis (doctoral)--Albertus-Universitat zu Konigsberg i. Pr., 1905.
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Thesis (doctoral)--Albertus-Universitat zu Konigsberg i. Pr., 1903.
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Thesis (doctoral)--Albertus-Universitat zu Konigsberg i. Pr., 1900.
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Thesis (doctoral)--Universitat zu Konigsberg i. Pr., 1900.
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Mode of access: Internet.
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The treatment of presbyopia has been the focus of much scientific and clinical research over recent years, not least due to an increasingly aging population but also the desire for spectacle independence. Many lens and nonlens-based approaches have been investigated, and with advances in biomaterials and improved surgical methods, removable corneal inlays have been developed. One such development is the KAMRA™ inlay where a small entrance pupil is exploited to create a pinhole-type effect that increases the depth of focus and enables improvement in near visual acuity. Short- and long-term clinical studies have all reported significant improvement in near and intermediate vision compared to preoperative measures following monocular implantation (nondominant eye), with a large proportion of patients achieving Jaeger (J) 2 to J1 (~0.00 logMAR to ~0.10 logMAR) at the final follow-up. Although distance acuity is reduced slightly in the treated eye, binocular visual acuity and function remain very good (mean 0.10 logMAR or better). The safety of the inlay is well established and easily removable, and although some patients have developed corneal changes, these are clinically insignificant and the incidence appears to reduce markedly with advancements in KAMRA design, implantation technique, and femtosecond laser technology. This review aims to summarize the currently published peer-reviewed studies on the safety and efficacy of the KAMRA inlay and discusses the surgical and clinical outcomes with respect to the patient’s visual function.
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Despite the wide availability of antiretroviral drugs, more than 250,000 infants are vertically infected with HIV-1 annually, emphasizing the need for additional interventions to eliminate pediatric HIV-1 infections. Here, we aimed to define humoral immune correlates of risk of mother-to-child transmission (MTCT) of HIV-1, including responses associated with protection in the RV144 vaccine trial. Eighty-three untreated, HIV-1-transmitting mothers and 165 propensity score-matched nontransmitting mothers were selected from the Women and Infants Transmission Study (WITS) of US nonbreastfeeding, HIV-1-infected mothers. In a multivariable logistic regression model, the magnitude of the maternal IgG responses specific for the third variable loop (V3) of the HIV-1 envelope was predictive of a reduced risk of MTCT. Neutralizing Ab responses against easy-to-neutralize (tier 1) HIV-1 strains also predicted a reduced risk of peripartum transmission in secondary analyses. Moreover, recombinant maternal V3-specific IgG mAbs mediated neutralization of autologous HIV-1 isolates. Thus, common V3-specific Ab responses in maternal plasma predicted a reduced risk of MTCT and mediated autologous virus neutralization, suggesting that boosting these maternal Ab responses may further reduce HIV-1 MTCT.
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En este trabajo se presenta la concepción aristotélica de la filosofía primera como ciencia de los principios y de las causas primeras según el libro primero de la Metafísica. Para ello, se distinguen tres momentos sucesivos que constituyen el análisis de la naturaleza y la meta que debe alcanzar esta ciencia: 1) la concepción de la sabiduría como ciencia que se ocupa de ciertos principios y causas; 2) la sabiduría como ciencia de los primeros principios y de las causas; 3) la determinación de las cuatro causas primeras como tarea de la filosofía primera. De este modo, se pretende mostrar que la Metafísica de Aristóteles es un intento para explicar las últimas cuestiones, el último porqué, indicando cuatro géneros diferentes de respuesta.
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El artículo pretende abordar el modo en el que la obra de Reiner Schürmann, a través de un original interpretación del pensamiento de Martin Heidegger, consigue desarrollar un tipo de filosofía política anárquica. Se intentará analizar, en la dispersa obra del filósofo holandés, la idea de anarquía como condición existencial, prestando especial atención al nexo entre el concepto de muerte de la metafísica y la posibilidad de una praxis política anárquica. El artículo se compone de tres partes: en la primera se examinará la noción de Ser y de “a priori práctico” en el trabajo de Schürmann. En la segunda se verá la diferencia entre el nihilismo del autor y el de Vattimo, y en la tercera, se profundizará en las consecuencias más propiamente políticas del pensamiento de Schürmann.
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We present optical photometry and spectroscopy of the optical transient SN 2011A. Our data span 140 days after discovery including BVRI u′g′r′i′z′ photometry and 11 epochs of optical spectroscopy. Originally classified as a type IIn supernova (SN IIn) due to the presence of narrow Hα emission, this object shows exceptional characteristics. First, the light curve shows a double plateau, a property only observed before in the impostor SN 1997bs. Second, SN 2011A has a very low luminosity (MV=-15.72), placing it between normal luminous SNe IIn and SN impostors. Third, SN 2011A shows low velocity and high equivalent width absorption close to the sodium doublet, which increases with time and is most likely of circumstellar origin. This evolution is also accompanied by a change in line profile; when the absorption becomes stronger, a P Cygni profile appears. We discuss SN 2011A in the context of interacting SNe IIn and SN impostors, which appears to confirm the uniqueness of this transient. While we favor an impostor origin for SN 2011A, we highlight the difficulty in differentiating between terminal and non-terminal interacting transients.
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En este trabajo nos proponemos analizar la colocación latina poena afficere, ‘imponer un castigo’, un tipo de colocación con especificidades tanto sintácticas como semánticas que la distinguen de las construcciones verbo-nominales más prototípicas: el sustantivo predicativo funciona no como Objeto Directo sino como tercer argumento del verbo soporte, un esquema sintáctico que, como intentaremos demostrar, resulta ideal para la expresión de predicados causativos. De los ejemplos documentados de poena afficere en un amplio corpus de textos, intentaremos destacar las principales características de este tipo de colocación. Para su descripción y formalización nos serviremos del marco teórico propuesto por la Teoría Sentido-Texto.