Multi-Fidelity Multidisciplinary Whole Engine Thermo-Mechanical Design Optimization

Traditionally, the optimization of a turbomachinery engine casing for tip clearance has involved either twodimensional transient thermomechanical simulations or three-dimensional mechanical simulations. This paper illustrates that three-dimensional transient whole-engine thermomechanical simulations can be used within tip clearance optimizations and that the efficiency of such optimizations can be improved when a multifidelity surrogate modeling approach is employed. These simulations are employed in conjunction with a rotor suboptimization using surrogate models of rotor-dynamics performance, stress, mass and transient displacements, and an engine parameterization.

Evidence-based management and intervention for autism spectrum disorders

Autism Spectrum Disorder (ASD) is diagnosed along a continuum of behavioural variants in social communication and repetitive behaviours [96]. Most individuals on the autism spectrum also experience differences in sensory perception. Some individuals on the spectrum are ‘high-functioning’ and able to cope in every day environments, while others are severely affected, non-verbal, and may have co-occurring diagnoses, such as intellectual disability, epilepsy, and/or obsessional, conduct, or mental health disorders. These individuals require substantial support, caring and careful management, and evidence-based, effective interventions.

Polybius’ ‘previous landslide’: Proof that Hannibal’s invasion route crossed the col de la traversette

Both Polybius and Livy described a landslide/landslip that blocked the Punic Army’s exfiltration from a high col on the water divide in the Western Alps. The landslide, more aptly termed rockfall, has been a source of contention amongst classicists for centuries despite the fact that only two cols—Clapier and Traversette—exhibit rockfall debris on the lee side of the Alps. While the Clapier rockfall is too small and too young to have provided blockage, the Traversette debris is nearly as Polybius described it when he retraced the invasion route some 60 years after the event. His ‘two-tier’ description of the deposit, a doublet of younger and older rock rubble, including measurements of width and volume are close to modern measurements and prove that he knew, in advance, the route Hannibal had followed. It would take a practiced eye to correctly identify the stratigraphic complexity inherent in the Traversette Rockfall. Here we present weathering ratios, soil stratigraphic, mineral, chemical and microbiological evidence in support of Polybius’ observations as a considerable background database for future geoarchaeological exploration.

Assessing the effect of reducing agents on the selective catalytic reduction of NOx over Ag/Al2O3 catalysts

The selective catalytic reduction (SCR) of NOx in the presence of different reducing agents over Ag/Al2O3 prepared by wet impregnation was investigated by probing catalyst activity and using NMR relaxation time analysis to probe the strength of surface interaction of the various reducing agent species and water. The results reveal that the strength of surface interaction of the reducing agent relative to water, the latter present in engine exhausts as a fuel combustion product and, in addition, produced during the SCR reaction, plays an important role in determining catalyst performance. Reducing agents with weak strength of interaction with the catalyst surface, such as hydrocarbons, show poorer catalytic performance than reducing agents with a higher strength of interaction, such as alcohols. This is attributed to the greater ability of oxygenated species to compete with water in terms of surface interaction with the catalyst surface, hence reducing the inhibiting effect of water molecules blocking catalyst sites. The results support the observations of earlier work in that the light off-temperature and maximum NOx conversion and temperature at which that occurs are sensitive to the reducing agent present during reaction, and the proposal that improved catalyst performance is caused by increased adsorption strength of the reducing agent, relative to water, at the catalyst surface. Importantly, the NMR relaxation time analysis approach to characterising the strength of adsorption more readily describes the trends in catalytic behaviour than does a straightforward consideration of the polarity (i.e., relative permittivity) of the reducing agents studied here. In summary, this paper describes a simple approach to characterising the interaction energy of water and reducing agent so as to aid the selection of reducing agent and catalyst to be used in SCR conversions.

Nacionalismo y poesía popular. Manuel Murguía y la invención de romancero gallego apócrifo

La anómala situación de los estudios sobre el Romancero de Galicia, y la indefinición de su propio estatuto como rama del Romancero hispánico, tienen su origen, en última instancia, en las posturas cambiantes que adoptó el primer nacionalismo cultural gallego, por razones ideológicas, ante el género de la poesía oral narrativa. Manuel Murguía es considerado hoy, por la amplitud y el eco de su obra, además de por su longevidad (1833-1923) y su papel como impulsor y heredero de la obra poética en gallego de Rosalía de Castro, como indiscutible padre fundador del galleguismo. Un nacionalismo gallego fundamentado en la tradición histórica y cultural tenía forzosamente que conceder gran importancia a las producciones de la poesía narrativa popular, como sucedió en el resto de la Europa coetánea. Sin embargo, a la altura de los 1860, se conocían solo muy escasas muestras de romances en Galicia, y su lengua era básicamente el castellano. El Romancero era así inservible como seña de identidad nacional o regional, y Murguía decidió dar la vuelta al argumento: la inexistencia de un Romancero gallego era en sí misma la prueba de un rasgo diferencial definitorio frente a Castilla. El conocimiento del Romancero portugués y una incipiente exploración de la tradición oral gallega llevaron, pocos años después, al “patriarca” a afirmar no sólo la existencia sino el esplendor de un Romanero gallego con características singulares. Tal romancero ha resultado ser producto de mixtificaciones de diverso grado realizadas por el propio Murguía y otros folcloristas. Se publica en este artículo la primera parte de un estudio, que irá seguida ulteriormente del inventario completo y análisis crítico de los romances gallegos alegados, y nunca publicados en colección, por Murguía.

“To laugh in tragic joy” – a linguagem poética de W. B. Yeats em Lapis Lazuli

Artigo em texto integral no link da versão do editor

Multicontrast connectometry: A new tool to assess cerebellum alterations in early relapsing-remitting multiple sclerosis.

BACKGROUND: Cerebellar pathology occurs in late multiple sclerosis (MS) but little is known about cerebellar changes during early disease stages. In this study, we propose a new multicontrast "connectometry" approach to assess the structural and functional integrity of cerebellar networks and connectivity in early MS. METHODS: We used diffusion spectrum and resting-state functional MRI (rs-fMRI) to establish the structural and functional cerebellar connectomes in 28 early relapsing-remitting MS patients and 16 healthy controls (HC). We performed multicontrast "connectometry" by quantifying multiple MRI parameters along the structural tracts (generalized fractional anisotropy-GFA, T1/T2 relaxation times and magnetization transfer ratio) and functional connectivity measures. Subsequently, we assessed multivariate differences in local connections and network properties between MS and HC subjects; finally, we correlated detected alterations with lesion load, disease duration, and clinical scores. RESULTS: In MS patients, a subset of structural connections showed quantitative MRI changes suggesting loss of axonal microstructure and integrity (increased T1 and decreased GFA, P < 0.05). These alterations highly correlated with motor, memory and attention in patients, but were independent of cerebellar lesion load and disease duration. Neither network organization nor rs-fMRI abnormalities were observed at this early stage. CONCLUSION: Multicontrast cerebellar connectometry revealed subtle cerebellar alterations in MS patients, which were independent of conventional disease markers and highly correlated with patient function. Future work should assess the prognostic value of the observed damage. Hum Brain Mapp 36:1609-1619, 2015. © 2014 Wiley Periodicals, Inc.

Finlande septentr:le, et merid:le, Nylande, et Tavastehus

1 kartta : vär. ; 42,5 x 57 cm, lehti 44,5 x 60,8 cm. Mittakaavaa ei määritelty.

Double formule d'une lettre d'indulgences datée de l'année 1539 et émanée du maître, des frères et des gouverneurs de l'hôpital Saint-Louis des Quinze-Vingt de Paris

[Acte. 1539]

L'Écho de Paris

1888/10/14 (Numéro 1666).

L'Écho de Paris

1888/08/18 (Numéro 1609).