Archives parlementaires de 1787 à 1860 ; 52-61, 63-82. Convention nationale. Série 1 / Tome 72 / impr. par ordre du Sénat et de la Chambre des députés ; fondé par MM. Mavidal et E. Laurent ; continué́ par M. L. Lataste,... M. Louis Claveau,... M. Constant Pionnier,... [et al.]

Collection : Les archives de la Révolution française ; 3.1

El oboe según Bach : estudio sobre la utilización del oboe en la obra de Johann Sebastian Bach

En este trabajo se relatan los acontecimientos que dieron pié a la relación simbiótica entre Johann Sebastian Bach y el oboe. Es un escrito de carácter divulgativo para el cual se consultaron tanto fuentes primarias como secundarias, las cuales se plasman aquí a manera de resumen. Como resultado de esta relación, nos ha llegado la colección más grande de música para oboe solista jamás escrita por un solo compositor.

Physical activity modulates heat shock protein-72 expression and limits oxidative damage accumulation in a healthy elderly population aged 60 90 years

BACKGROUND: Reactive oxygen species production increases during aging, whereas protective mechanisms such as heat shock proteins (HSPs) or antioxidant capacity are depressed. Physical activity has been hypothesized to provide protection against oxidative damage during aging, but results remain controversial. This study aimed to investigate the effect of different levels of physical activity during aging on Hsp72 expression and systemic oxidative stress at rest and in response to maximal exercise. METHODS: Plasma antioxidant capacity (Trolox equivalent antioxidant capacity, TEAC), thiobarbituric acid-reactive species (TBARS), advanced oxidized proteins products (AOPP), and Hsp72 expression in leukocytes were measured before and after maximal exercise testing in 32 elderly persons (aged 73.2 years), who were assigned to two different groups depending on their level of physical activity during the past 12 months (OLow = moderate to low level; OHigh = higher level). RESULTS: The OHigh group showed higher aerobic fitness and TEAC (both representing 120% of OLow values) as well as lower oxidative damage (50% of OLow values) and Hsp72 expression. Exercise led to a lower increase in oxidative damage in the OHigh group. Aerobic fitness was positively correlated with TEAC and negatively with lipid peroxidation (TBARS). Hsp72 expression was negatively correlated with TEAC but positively correlated with TBARS levels. CONCLUSIONS: The key finding of this study is that, in people aged 60 to 90 years, long-term high level of physical activity preserved antioxidant capacity and limited oxidative damage accumulation. It also downregulated Hsp72 expression, an adaptation potentially resulting from lower levels of oxidative damage.

Involvement of Dab1 in APP processing and [beta]-amyloid deposition in sporadic Creutzfeldt-Jakob patients.

Alzheimer"s disease and prion pathologies (e.g., Creutzfeldt-Jakob disease) display profound neural lesions associated with aberrant protein processing and extracellular amyloid deposits. For APP processing, emerging data suggest that the adaptor protein Dab1 plays a relevant role in regulating its intracellular trafficking and secretase-mediated proteolysis. Although some data have been presented, a putative relationship between human prion diseases and Dab1/APP interactions is lacking. Therefore, we have studied the putative relation between Dab1, APP processing and Aβ deposition, targets in sCJD cases. Our biochemical results categorized two groups of sCJD cases, which also correlated with PrPsc types 1 and 2 respectively. One group, with PrPsc type 1 showed increased Dab1 phosphorylation, and lower βCTF production with an absence of Aβ deposition. The second sCJD group, which carried PrPsc type 2, showed lower levels of Dab1 phosphorylation and βCTF production, similar to control cases. Relevant Aβ deposition in the second sCJD group was measured. Thus, a direct correlation between Dab1 phosphorylation, Aβ deposition and PrPsc type in human sCJD is presented for the first time.

Friday Facts, September 24, 2010, Vol. 72

Bureau of Nutrition and Health Promotion part of the Iowa Department of Public Health produces of weekly newsletter about the Iowa WIC Program for the State of Iowa citizen.

72. [Jeune femme portant des parures de bijoux] / [mission Joseph Vassal]

Donateur : Vassal, Gabrielle Maud (1880-1959)

[Illustration de Musicus curio sus oder Battalus, der Voruitzige Musicant...] / [Non identifié] ; Johann Kuhnau, aut. du texte

Comprend : [ Frontispice. Scène dans un jardin. Homme à son instrument : accordage d'un clavecin ? XVIIè siècle.] [ Cote : BNF B 43435. ]

[Johann Samuel Heinrich Kiepert] / phot. L. Haase & co.

Donateur : Maunoir, Charles (1830-1901)

[Illustrations de Kalendarium] / [Non identifié] ; Johann Regiomontanus, aut. du texte

Comprend : [Pl. : calendrier d es éclipses de lune et de soleil de 1475 à 1479.] [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : calendrier d es éclipses de lune et de soleil de 1479 à 1482.] [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : calendrier d es éclipses de lune et de soleil de 1483 à 1487.] [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : calendrier d es éclipses de lune et de soleil de 1487 à 1491.] [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : calendrier d es éclipses de lune et de soleil de 1493 à 1497.] [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : calendrier d es éclipses de lune et de soleil de 1497 à 1504.] [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : calendrier d es éclipses de lune et de soleil de 1505 à 1513.] [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : calendrier d es éclipses de lune et de soleil de 1515 à 1518.] [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : calendrier d es éclipses de lune et de soleil de 1519 à 1523.] [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : calendrier d es éclipses de lune et de soleil de 1523 à 1530.] [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : cadran solaire.] Instrumentum Horarum inaequalium. [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : calendrier lunaire.] Instrumentum veri motus lunae minue. Adde. [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : cadran solaire.] Quadrans Horologii Horizontalis. [Cote : Res g V 57/Microfilm R 16374] ; [Pl. : cadran solaire.] Quadratum Horarium Generale. [Cote : Res g V 57/Microfilm R 16374]