985 resultados para RW-TRI
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National Highway Traffic Safety Administration, Washington, D.C.
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National Highway Traffic Safety Administration, Washington, D.C.
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"Prilozhenīi͡a: 1) Russkīĭ teatr XVIII v. 2) Voronezhskoe kulʹturnoe gni͡ezdo. 3) Turgenev i 60-ye gody."
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Cover title.
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Mode of access: Internet.
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Photocopy.
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Mode of access: Internet.
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Includes index.
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Bound as issued with Sveti postni Evangelji za vsah dan vʹ postu.
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Photocopy.
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Contiene en las primeras páginas sin numerar: Ex libris Petri Criniti De historia, ac oratoribus Latinis, Sallustii uita. - Rursus alia Sallustii uita, incerto autore. - Iacobi Bononiensis in Catilinam Sallustii annotatiunculae. - Fragmentum Orationis Ciceronis pro M. Caelio.
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Thesis (doctoral)--
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Thesis (doctoral)--
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Group A streptococcus (GAS) is responsible for causing many clinical complications including the relatively benign streptococcal pharyngitis and impetigo. However. if left untreated. these conditions may lead to more severe diseases such as rheumatic fever (RF) and rheumatic heart disease (RHD). These diseases exhibit high morbidity and mortality, Particularly in developing countries and in indigenous populations of affluent countries. Only ever occur following GAS infection, a vaccine offers Promise for their Prevention. As stich, we have investigated the Use of the lipid-core peptide (LCP) system for the development of multi-valent Prophylactic GAS vaccines. The current study has investigated the capacity of this system to adjuvant LIP to four different GAS peptide epitopes. Presented are the synthesis and immunological assessment of tetra-valent and tri-valent GAS LCP systems. We demonstrated their capacity to elicit systemic IgG antibody responses in B10.BR mice to all GAS peptide epitopes. The data also showed that the LCP systems Were self-adjuvanting. These findings are particularly encouraging for the development of multi-valent LCP-based GAS vaccines.