Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology

In this consensus document we summarize the current knowledge on major asthma, rhinitis, and atopic dermatitis endotypes under the auspices of the PRACTALL collaboration platform. PRACTALL is an initiative of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology aiming to harmonize the European and American approaches to best allergy practice and science. Precision medicine is of broad relevance for the management of asthma, rhinitis, and atopic dermatitis in the context of a better selection of treatment responders, risk prediction, and design of disease-modifying strategies. Progress has been made in profiling the type 2 immune response-driven asthma. The endotype driven approach for non-type 2 immune response asthma, rhinitis, and atopic dermatitis is lagging behind. Validation and qualification of biomarkers are needed to facilitate their translation into pathway-specific diagnostic tests. Wide consensus between academia, governmental regulators, and industry for further development and application of precision medicine in management of allergic diseases is of utmost importance. Improved knowledge of disease pathogenesis together with defining validated and qualified biomarkers are key approaches to precision medicine.

Protein Hydrolysis and Nitrogen Remobilisation in Plant Life and Senescence

In plant cells, as in all other cells, proteins are submitted to permanent turnover, and the intracellular content of a given protein depends on its rate of both synthesis and degradation. The life time of most proteins is shorter than that of the cell. Thus, in young leaves of Lemna minor, the average half-life of protein was estimated to be 7 days, and it was shorter under stress conditions (Davies 1982). Such observations mean that nitrogen and amino acid fluxes are both cylic and permanent. Although protein turnover may appear wasteful, in terms of energy, numerous studies have shown that proteolysis provides multiple functions in cell physiology, and is an essential regulatory mechanism of cell metabolism and development.

Shoreline plant establishment and use of a wave-stilling device /

"January 1978."

Ethylmercury : formation in plant tissues and relation to methylmercury formation /

Mode of access: Internet.

Seed list : a list of forage plant seeds and the incidental seeds commonly found with them.

Cover title.

Livestock health encyclopedia; the control of diseases and parasites in cattle, sheep and goats, swine, horses and mules. /

Bibliography: p. 605-613.

Sheep, their management and breeding. The various breeds, methods of rearing, fattening and marketing; diseases and ailments, with remedies, etc.

Mode of access: Internet.

Biotechnology in agriculture, 1986-May 1992 : citations from AGRICOLA concerning diseases and other environmental considerations /

"August 1992."

Radioisotopes in agriculture : analytical procedures, animal husbandry, entomology, fertilizer uptake, general studies, photosynthesis, plant genetics, and plant physiology : a selected bibliography /

"TID-3078(Suppl. 1). Biology and Medicine, TID-4500 (31st edition)."

National plant, flower and fruit guild magazine,

Mode of access: Internet.

Wisconsin soil testing plant analysis and feed and forage analysis procedures /

"Revised 1977"--cover.

Facts for farmers : also for the family circle : a compost of rich materials for all landowners, about domestic animals and domestic economy, farm buildings, gardens, orchards, and vineyards : and all farm crops, tools, fences, fertilization, draining, and irrigation : with an appendix on the diseases and cures of domestic animals /

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A treatise on the diseases and physical education of children ...

Error in paging: nos. 549-556 omitted.

Report and recommendations of the Plant Science and Entomology Research Advisory Committee : developed at its meeting, February 6-10, 1967, Wheaton, Maryland.

Mode of access: Internet.