954 resultados para POISONING PSP TOXINS
Resumo:
Mode of access: Internet.
Resumo:
Description based on: Jan. 1-Dec. 31, 1967; title from caption.
Resumo:
Mode of access: Internet.
Resumo:
Description based on: 1994; title from cover.
Resumo:
"April 1992."
Resumo:
Includes bibliographical references (p. 16)
Resumo:
"May, 1992."
Resumo:
Vol. 2 translated by R. May ; v. 3 by Mrs. Ievers.
Resumo:
Mode of access: Internet.
Resumo:
Mode of access: Internet.
Resumo:
Includes index.
Resumo:
Mode of access: Internet.
Resumo:
Mode of access: Internet.
Resumo:
Nerve sprouts emerge from motor nerve terminals following blockade of exo-endocytosis for more than 3 days by botulinum neurotoxin (BoNT), and form functional synapses, albeit temporary. Upon restoration of synaptic activity to the parent terminal 7 and 90 days after exposure to BoNT/F or A respectively, a concomitant retraction of the outgrowths was observed. BoNT/E caused short-term neuroparalysis, and dramatically accelerated the recovery of BoNT/A-paralyzed muscle by further truncation of SNAP-25 and its replenishment with functional full-length SNARE. The removal of 9 C-terminal residues from SNAP-25 by BoNT/A leads to persistence of the inhibitory product due to the formation of a nonproductive SNARE complex(es) at release sites, whereas deletion of a further 17 amino acids permits replenishment and a speedy recovery. (C) 2003 Elsevier Science (USA). All rights reserved.