[Marie Joseph Gustave Adolphe Lambert]

Donateur : Jackson, James (1843-1895)

[Louis Marie François Tardy de Montravel] / Franck

Donateur : Jackson, James (1843-1895)

[Léonel Delisle Marie François René, Marquis de Moustier] / L. Pierson

Donateur : Jackson, James (1843-1895)

[Marie Armand Pascal d'Avezac de Castera Macaya] / N. Georges

Donateur : Maunoir, Charles (1830-1901)

The characteristics of gait in Charcot-Marie-Tooth disease types I and II.

Certain typical gait characteristics such as foot-drop and foot supination are well described in Charcot-Marie-Tooth disease. These are directly related to the primary disease and due to the weakness of ankle dorsiflexors and everters characteristic of this hereditary neuropathy. We analysed 16 subjects aged 8-52 years old (11 with type I, 5 with type II Charcot-Marie-Tooth disease) using three-dimensional gait analysis and identified kinematic features previously unreported. These patients showed a combination of tight tendo achillei, foot-drop, failure of plantar flexion and increased foot supination, but also presented with excessive internal rotation of the knee and/or tibia, knee hyperextension in stance, excessive external rotation at the hips and decreased hip adduction in stance (typical of a broad based gait). These proximal features could have been an adaptation to or consequence of the disrupted ankle and foot biomechanics, however a direct relation to the neuropathy is also possible since sub-normal muscle power was observed at the proximal levels in most subjects on both manual testing and kinetic analysis. Gait analysis is a useful tool in defining the characteristic gait of patients with Charcot-Marie-Tooth disease.

[Louis Marie Meschinet de Richemond] / Th. Cognacq

Donateur : Association française pour l'avènement des sciences