1000 resultados para Organismos alvo


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The study area is located in the geological parameters of the Pilar de Goiás Greenstone Belt (GO), it is part of the Pilar de Goias Group’s meta-volcano-sedimentary sequence. This is a homoclinal package constituted by terrigenous metassediments containing intercalations of meta-ultramafic rocks and iron formations. The units that were informally named in this work, are interpreted as belongs to the Serra do Moinho Formation. Through mineralogical associations the area’s metamorphism were classified as high greenschist facies garnet zone. Prior to this work were detected in the area, through soil samples, some auriferous anomalies. One of the objectives of this work is the detection of possibles hidrotermal alterations related to these anomalies presents in the study area

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Os herbicidas a base de glifosato, como a formulação comercial Roundup®, tem sido amplamente utilizado para o controle de ervas daninhas na agricultura brasileira. O uso desses herbicidas podem resultar no rompimento do equilíbrio ecológico, podendo causar danos a organismos não- alvo, como os peixes. Para testar se o glifosato altera comportamento de peixes, utilizamos o Geophagus brasiliensis, nativo de várias regiões do Brasil, espécie territorialista e que se utiliza de confrontos agonísticos para estabelecer hierarquia de dominância. Neste estudo, encontramos o valor da concentração letal capaz de promover a morte de 50% da população em 96 horas (CL₅₀,₉₆h= 1,8 mgL⁻1). No entanto, nos testes de interações agonísticas foi utilizado uma dosagem subletal de 0,72 mgL⁻1, afim de avaliar possíveis alterações na agressividade de Geophagus brasiliensis. Testamos o efeito de glifosato em um grupo experimental, e um grupo controle com peixes que não foram expostos ao herbicida glifosato. Um etograma foi elaborado para quantificar as interações agonísticas. Ao comparar os dois tratamentos, foi possível observar um aumento no número de interações agonísticas no grupo exposto ao glifosato em relação ao grupo controle. No pareamento entre peixes tratados versus peixes não tratados, a média de interações foi maior para o peixe não tratado (controle) e a latência para os confrontos desse grupo foi menor, indicando que a exposição ao herbicida Roundup®promove, possivelmente, alterações físicas e/ou químicas nos animais e esses sinalizam de alguma forma para o seu oponente

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The arthritis-encephalitis caprine vírus is found at mostly areas of the world, especially at the countries that milk goats is strongly tecnific, and already was found in many brasilian states. The illness causes greats econimics prejudice, influencing badly the productive life time of the flock, related with the low production, decrease of the reproductive performance and lost of the genetic potential, determining constants flock’s renew. Many authors calls the atention for the probable dissemination of the illness and reinforce the necessity of the adoption strong sanitary politics for the illnes control. The controls programs, basically, based on knowledeg of the target-cells, that keep and distribute the virus on the guests organisms; on the transmition way; on sensibility and specificity of the sorologics tests, as well as your frequency of realitation in the flock; and after all on the management that the flock is submeted

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The huge demand for procedures involving ionizing radiation promotes the need for safe methods of experimentation considering the danger of their biological e ects with consequent risk to humans. Brazilian's legislation prohibits experiments involving this type of radiation in humans through Decree 453 of Ministry of Health with determines that such procedures comply with the principles of justi cation, optimization and dose limitation. In this line, concurrently with the advancement of available computer processing power, computing simulations have become relevant in those situations where experimental procedures are too cost or impractical. The Monte Carlo method, created along the Manhattan Project duringWorldWar II, is a powerful strategy to simulations in computational physics. In medical physics, this technique has been extensively used with applications in diagnostics and cancer treatment. The objective of this work is to simulate the production and detection of X-rays for the energy range of diagnostic radiology, for molybdenum target, using the Geant4 toolkit. X-ray tubes with this kind of target material are used in diagnostic radiology, speci cally in mammography, one of the most used techniques for screening of breast cancer in women. During the simulations, we used di erent models for bremsstrahlung available in physical models for low energy, in situations already covered by the literature in earlier versions of Geant4. Our results show that although the physical situations seems qualitatively adequate, quantitative comparisons to available analytical data shows aws in the code of Geant4 Low Energy source

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The Roosevelt-Domain Aripuanã that by Filho et al 2004 is characterized by a metavolcanic sedimentary sequence, containing acidic to interemediary metavolcanic rocks and clastic and chemical sediments, deformed and metamorphosed at low grade, with U-Pb age of 1.743 +- 4 Ma, (by Granito Zé do Torno), and circumscribed bodies of granites late to post-orogenic (Aripuanã)...

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The Therapy with proton beam has shown more e ective than Radiotherapy for oncology treatment. However, to its planning use photon beam Computing Tomography that not considers the fundamentals di erences the interaction with the matter between X-rays and Protons. Nowadays, there is a great e ort to develop Tomography with proton beam. In this way it is necessary to know the most likely trajectory of proton beam to image reconstruction. In this work was realized calculus of the most likely trajectory of proton beam in homogeneous target compound with water that was considered the inelastic nuclear interaction. Other calculus was the analytical calculation of lateral de ection of proton beam. In the calculation were utilized programs that use Monte Carlo Method: SRIM 2006 (Stopping and Range of Ions in Matter ), MCNPX (Monte Carlo N-Particle eXtended) v2.50. And to analytical calculation was employed the software Wolfram Mathematica v7.0. We obtained how di erent nuclear reaction models modify the trajectory of proton beam and the comparative between analytical and Monte Carlo method

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The study area of the Guarda-Mor target (Israelândia-GO) contextualizes the terrains of the estaern portion of the Arenópolis Magmatic Arc, more accurately, the Neoproterozoic associations inserted in the field of the Jaupaci volcano-sedimentary sequence. The mapped area is located in the central-western of Goiás state. The presente paper has as main objective to characterize the structural, petrographic and litogeochemistry of the target rocks beyond to compare these factors with the Mina Bacilândia rocks (Fazenda Nova-GO) in order to assess the genetic similarity of volcano-sedimentary units and deposits associated. The Guarda-Mor target is represented by the Jaupaci metavolcanic rocks sequence presenting bimodal volcanism. This sequence consists in metafelsic rocks like sericite/muscovite quartz schist, phyllite and metarriolites and/or metariodacites with calc-alkaline geochemical signature and metamafic rocks with tholeiitic character formed by actinolite - chlorite schist and chlorite - quartz schist. Besides the package of supracrustal rocks also can be observed the occurrence of a local intrusion syn- to late - tectonic named Granito Subvulcânico. In the study area beyond the marked volcanism also seen an event of crustal melting granitogênese evidenced by the presence of 2 granites at the east and the west of the map, Granito Israelândia and Granito Iporá respectively. Structural analysis both at the macro and micro have identified 3 deformation phases. The types of rock on the region record features in the metamorphic facies top and down. These features were subdivided into 3 metamorphic areas: the east and West areas show thermal metamorphism due to intrusion of adjacente granites while the central domain displays features of regional metamorphism. Gold mineralization of the Guarda –Mor deposit target suggests a possible structural control beyond pronounced the hydrothermal alteration. The mineralization may also be...

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Small non coding RNAs emerged as important characters in several biology aspects. Among then, the most studied are microRNAs (miRNAs) and short interfering RNAs (siRNAs), that regulate their target gene post-transcriptionally in plants, animals and RNAi pathway intermediates, respectively. Both of classes have similar biogenesis being processed by Dicer enzymes and subsequent association with Argonaute enzymes. In plants, miRNAs and siRNAs have important functions in development, genome integrity and biotic and abiotic stress responses. The advances in high-throughtput sequencing and in silico analisys provide the uncover of new small non coding RNAs classes, many of them with unknown functions and biogenesis. tRNA derived small RNAs (tRFs) are a small non coding RNA class, that have as precursor a tRNA molecule. These were uncovers in the last decade in many organisms and, recently, in plants. Recent works detected tRFs from different sizes, with different source portions of the mature tRNA molecule (5’ end; 3’ end, anti-codon loop) and some from the tRNA precursor (pre-tRNA), suggesting that may be a novel class of small RNA and not random degradation products. Works in humans showed that some tRFs are processed by the Dicer enzymes, have association with the Argonaute enzymes and cell differentiation, tumor appearance and gene silencing related functions. Works in Arabidopsis and pumpkin (Cucurbita maxima) showed, respectively, that the tRFs have nutritional stress response possible functions and long distance signaling function between source and drain tissues, and may affect the translation. The tRFs biogenesis in plants are, until now an unknown, absence information about it in the literature and its possible biological functions are few studied yet, making then interesting target for studies among the small non coding RNAs in plants

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The oil and biodiesel are oily substances which, if spilled or thrown out in the environment, can cause serious damages. In this context, bioremediation techniques can be used to the recovering of sites degradated by mineral or vegetable oil, besides them, the biodegradation. However, it is necessary that there are microorganism strains used to degradate the contaminant, previously selected for the fast, efficient and minimum impact remediation. The main objective of this study was to isolate microorganism strains coming from different ecological recesses and verify their potentiality on biodegradating oil and biodiesel. Strains of bacteria, fungi and yeasts were isolated from soils contaminated by hydrocarbons (diesel, gasoline, grease) before, by doing striations on culture plates. On the biodegradation tests, it was used the redox indicator, 2,6-dichlorophenol indophenol (DCPIP), then, after the indicador’s discoloration, the absorbance of the suspension obtained was measured. 46 different microorganism strains were isolated, and the oil, when it was used as a carbon resource, it was degradate easier than the biodiesel. The experiments showed that, in a period, the site impacted by oil spills recovers itself by the biodegradation, in aerobic conditions, by the redox activity.

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The following work refers to a geologic mapping in the Morro do Corcunda target, located between the cities of Pilar of Goiás and Santa Terezinha in the northwest portion of the State of Goiás. This mapping was carried through in 1:10,000 scale and covers an area of approximately 60km2. Collections of samples had been carried through for laborarorial analysis, and from those twenty-three thin scetions have been produced in order to describe the main lithologies that occur in the area. It was possible to observe anomalous gold targets in the region through chip samples carried through during the stage of field work. The gathered field data and the ones that have been made available by the company Yamana Gold Incorporation were congregated, and a data integration was carried through. This integration made possible the correlation of the litologies found in field with the Greenstone Belt Pilar de Goiás sequence and the structural evolution of the area.

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O estudo de novas alternativas terapêuticas no tratamento de infecções microbianas tornou-se crescente no cenário científico devido à grande variação genética desses micro-organismos, que resultou na resistência aos antimicrobianos existentes. A grande diversidade na flora brasileira e a ampla utilização das plantas como medicamentos pela população justificam os estudos e o crescente interesse pela descoberta de novos compostos bioativos isolados dos vegetais. Plantas usualmente utilizadas na agricultura, apenas como adubação verde, por exemplo, são atualmente alvo de estudos científicos com potenciais promissores de atuação como de produtos terapêuticos. Plantas da família Leguminosae, amplamente conhecidas e utilizadas como fornecedoras de nitrogênio ao solo, vem sendo estudadas por diversas áreas da saúde para comprovarem a ação de compostos isolados entre estes os alcalóides pirrolidizínicos como antiinflamatórios, antibióticos e até como veneno para pragas. O objetivo do presente estudo foi determinar, a partir de extrativos de Crotalaria pallida, a atividade antimicrobiana in vitro utilizando cepas padrões de: Staphylococccus aureus, Escherichia coli, Salmonella sp e da levedura Candida albicans. Para determinação dessa atividade foi utilizada a técnica de diluição em microplaca que possibilitou o estudo da atividade do extrativo vegetal e da concentração inibitória mínima, isto é, concentração bactericida e/ou bacteriostática mínima e concentração fungiostática e/ou fungicida mínima. A Crotalaria pallida, não apresentou atividade frente aos micro-organismos testados nas condições padronizadas neste estudo

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Eight Mesoproterozoic granite suites are recognized in the Rondônia Tin Province, called Serra da Providência Intrusive Suite (1606-1532 Ma), Rio Crespo Intrusive Suite (1500 Ma), St. Anthony Intrusive Suite (1406 Ma), Teotonio Intrusive Suite (1387 Ma ), Santa Clara Intrusive Suite (1082-1074 Ma) and Younger Granites of Rondônia Intrusive Suite (998-974 Ma), represent successive magmatic type A (anorogenic) and the intra-plate basement rocks intruded in the metamorphic complex named Jamari separated into two distinct lithologic associations, a ortogneiss (U-Pb from 1.76 to 1.73 Ga) and a paragneiss (1675 + / - 12 Ma). Tin mineralization are widely found in the Tin Province and are associated with granitic intrusions known Mesoproterozoic more closely with the last two magmatic events, represented by the Santa Clara and Younger Granites of Rondônia. The tin mineralization are of primary and secondary, with the primary form deposits of different structural styles and is presented in the form of endo-or exogreisens, veins, stockworks and pegmatites. The secondary mineralization are related to natural processes of weathering and erosion of primary rocks, leading to placer deposits classified as colluvial, eluvial and colluvial-alluvial. The Target Alvo Sol Nascente is located in the central-eastern Rondônia Tin Province and has basement rocks of the metamorphic-magmatic region represented by Jamari Complex intrusive suites and Sierra Providence and Rio Crespo. The last tectonic event spa in the area was responsible for the intrusion of Younger Granites of Rondônia (São Carlos and Caripuanã Massifis). The anomalous levels of tin, sufficient to operate (Mina Rising Sun), indicate that there was possibly mineralization event, evidenced by pegmatite veins well defined, easily found relatively close to mine. Plaque deposits associated with Quaternary sedimentary sequences can also be observed

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Os carrapatos são considerados um dos mais importantes grupos dentre os artrópodes, por serem vetores de agentes patogênicos, que podem atacar animais, bem como o próprio homem. Dentre as diversas espécies de carrapato destaca-se a do Rhipicephalus sanguineus, pertencente à família Ixodidae e com ampla distribuição em todos os continentes. Atualmente esta espécie é considerada uma praga urbana, de grande importância médico-veterinária, que parasita principalmente o cão doméstico. Os ovários de carrapatos são considerados órgãos vitais para o sucesso biológico deste grupo de animais. Neste sentido, desenvolver pesquisas para se conhecer a ação de produtos naturais com reconhecida ação repelente ou acaricida, sobre o sistema reprodutor feminino de carrapatos, traria importantes informações para um melhor entendimento dos efeitos da ação destes produtos nos ovócitos desses ectoparasitas, contribuindo principalmente para o desenvolvimento de métodos de controle alternativos menos tóxicos para os organismos não-alvo e menos poluentes para o meio ambiente. Dessa forma, o presente estudo analisou as alterações morfofisiológicas causadas por diferentes concentrações do óleo de andiroba no ovário de fêmeas semiingurgitadas de carrapatos R. sanguineus

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A large amount of external factors that can foster the emergence of free radicals in organisms has created a imminent need for understanding and technologies that enables the search of antioxidant componds and extraction of antioxidants from natural sources. These compounds have great potential for kidnapping free radicals which are highly harmful to organisms, being the principal responsible for the decrease in the shelf life of foods, and aging. These free radicals are also related to diseases such as AIDS, arthritis, diabetes, heart disease and others. Fruits and vegetables are true mines of compounds with antioxidant potential, its vitamins and phenolic compounds present an essential role in the nutrition of living beings acting as a defense against degradation of lipids and proteins, which indicates the importance of a diet rich in these nutrients, given that part of the antioxidant defenses of the body comes from the diet. This revision study aims to put in evidence the indispensable role of antioxidants in the survival of organisms.