Diaspora and Trust : Cuba, Mexico, and the Rise of China /

Examines the growing relationship between Latin America and China, focusing on the sociological, rather than the economic or military, dimension of this connection. This title was made Open Access by libraries from around the world through Knowledge Unlatched.

The Catholic churches of Boston and its vicinity and St. John's Seminary, Brighton, Mass. : a folio of photo-gravures with notes and historical information /

"Edition de Luxe."

Assessing Temperament as a Predictor of Distress at Anesthesia Induction Using the Children’s Behavior Questionnaire Short Form

Thesis (Master's)--University of Washington, 2016-06

Bandwidth requirements for shallow, high-resolution seismic reflection

The optimum bandwidth for shallow, high-resolution seismic reflection differs from that required for conventional petroleum reflection. An understanding of this issue is essential for correct choice of acquisition instrumentation. Numerical modelling of simple Bowen Basin coal structures illustrates that, for high-resolution imaging, it is important to accurately record all frequencies up to the limit imposed by earth scattering. On the contrary, the seismic image is much less dependent on frequencies at the lower end of the spectrum. These quantitative observations support the use of specialised high-frequency geophones for high-resolution seismic imaging. Synthetic seismic inversion trials demonstrate that, irrespective of the bandwidth of the seismic data, additional low-frequency impedance control is essential for accurate inversion. Inversion provides no compelling argument for the use of conventional petroleum geophones in the high-resolution arena.

The use of the Dade County student assistance profile in the identification of at -risk students at a minority senior high school

Current high school completion rates in Dade County and across the nation are considered to be unacceptable. This has led to the development of student assistance profiles to aid in the early identification of students considered to be at risk to allow for some form of intervention. The purpose of this research was to examine the current Dade County Public Schools profile as applied to one specific high school in which most of the students are Hispanic (mostly of Mexican descent) and Black (African-Americans, as well as recent Haitian immigrants). Additionally, the effectiveness of the alternative intervention program provided at this high school--a school within a school--were evaluated. School records of the 1992 in-coming ninth grade class became the initial data base. The individual student records of this cohort were then examined over a four-year period until their expected date or graduation. The DCPS profile used to identify potential dropouts from this group was evaluated, using chi-square and multivariate analysis, to determine its overall effectiveness, as well as the effectiveness of the individual indicators which comprise the profile. The Student Assistance Profile was found to an effective predictor, but it over-identified students from this cohort, particularly minorities, to the extent that it became largely ineffective, especially considering the limited resources available for intervention. The intervention program was found to be ineffective in reducing the dropout rate. Further analysis of the individual indicators used in the DCPS profile as they applied to this school population resulted in the development of an improved profile. By reducing the number of indicators to those found to be most highly associated with failure to graduate--academic performance and absences--a simpler student assistance profile was developed which appears to be better suited to high schools with similar demographics and budget restraints. ^

A deimmunised form of the ribotoxin, α-sarcin, lacking CD4+ T cell epitopes and its use as an immunotoxin warhead

Fungal ribotoxins that block protein synthesis can be useful warheads in the context of a targeted immunotoxin. α-Sarcin is a small (17 kDa) fungal ribonuclease produced by Aspergillus giganteus that functions by catalytically cleaving a single phosphodiester bond in the sarcin–ricin loop of the large ribosomal subunit, thus making the ribosome unrecognisable to elongation factors and leading to inhibition of protein synthesis. Peptide mapping using an ex vivo human T cell assay determined that α-sarcin contained two T cell epitopes; one in the N-terminal 20 amino acids and the other in the C-terminal 20 amino acids. Various mutations were tested individually within each epitope and then in combination to isolate deimmunised α-sarcin variants that had the desired properties of silencing T cell epitopes and retention of the ability to inhibit protein synthesis (equivalent to wild-type, WT α-sarcin). A deimmunised variant (D9T/Q142T) demonstrated a complete lack of T cell activation in in vitro whole protein human T cell assays using peripheral blood mononuclear cells from donors with diverse HLA allotypes. Generation of an immunotoxin by fusion of the D9T/Q142T variant to a single-chain Fv targeting Her2 demonstrated potent cell killing equivalent to a fusion protein comprising the WT α-sarcin. These results represent the first fungal ribotoxin to be deimmunised with the potential to construct a new generation of deimmunised immunotoxin therapeutics.

Geochemistry and minerals at DSDP Legs 68-70 Holes

The compositions of natural glasses and phenocrysts in basalts from Deep Sea Drilling Project Sites 501, 504, and 505, near the Costa Rica Rift, constitute evidence for the existence of a periodically replenished axial magma chamber that repeatedly erupted lavas of remarkably uniform composition. Magma compositions were affected by three general components: (1) injected magmas carrying (in decreasing order of abundance) Plagioclase, olivine, and chrome-spinel phenocrysts (spinel assemblage); (2) injected magmas carrying Plagioclase, clinopyroxene, and olivine phenocrysts, but no spinel (clinopyroxene assemblage); and (3) moderately evolved hybrids in the magma chamber itself. The compositions of the injected phenocrysts and minerals in glomerocrysts are as follows: Plagioclase - An85-94; olivine - Fo87-89; clinopyroxene - high Cr2O3 (0.7-1.1%), endiopside (Wo42En51Fs7), and aluminous chromian spinel (Cr/Cr + Al = 0.3). These minerals resemble those thought to occur in upper mantle sources (9 kbars and less) of ocean-ridge basalts and to crystallize in magmas near those sources. In the magma chamber, more sodic Plagioclase (An79-85), less magnesian olivine (Fo81-86) and low-Cr2O3 (0.1-0.4%) clinopyroxene formed rims on these crystals, grew as other phenocrysts, and formed cumulus segregations on the walls and floors of the magma chamber. In the spinel-assemblage magmas, magnesiochromite (Cr/Cr + Al = 0.4-0.5) also formed. Some cumulus segregations were later entrained in lavas as xenoliths. The glass compositions define 16 internally homogeneous eruptive units, 13 of which are in stratigraphic order in a single hole, Hole 504B, which was drilled 561.5 meters into the ocean crust. These units are defined as differing from each other by more than analytical uncertainty in one or more oxides. However, many of the glass groups in Hole 504B show virtually no differences in TiO2 contents, Mg/Mg + Fe2+, or normative An/An + Ab, all of which are sensitive indicators of crystallization differentiation. The differences are so small that they are only apparent in the glass compositions; they are almost completely obscured in whole-rock samples by the presence of phenocrysts and the effects of alteration. Moreover, several of the glass units at different depths in Hole 504B are compositionally identical, with all oxides falling within the range of analytical uncertainty, with only small variations in the rest of the suite. The repetition of identical chemical types requires (1) very regular injection of magmas into the magma chamber, (2) extreme similarity of injected magmas, and (3) displacement of very nearly the same proportion of the magmas in the chamber at each injection. Numerical modeling and thermal considerations have led some workers to propose the existence of such conditions at certain types of spreading centers, but the lava and glass compositions at Hole 504B represent the first direct evidence revealed by drilling of the existence of a compositionally nearly steady-state magma chamber, and this chapter examines the processes acting in it in some detail. The glass groups that are most similar are from clinopyroxene-assemblage lavas, which have a range of Mg/Mg + Fe2"1" of 0.59 to 0.65. Spinel-assemblage basalts are less evolved, with Mg/Mg + Fe2+ of 0.65 to 0.69, but both types have nearly identical normative An/An + Ab (0.65-0.66). However, the two lava types contain megacrysts (olivine, Plagioclase, clinopyroxene) that crystallized from melts with Mg/Mg + Fe2+ values of 0.70 to 0.72. Projection of glass compositions into ternary normative systems suggests that spinel-assemblage magmas originated deeper in the mantle than clinopyroxene-assemblage magmas, and mineral data indicate that the two types followed different fractionation paths before reaching the magma chamber. The two magma types therefore represent neither a low- nor a high-pressure fractionation sequence. Some of the spinel-assemblage magmas may have had picritic parents, but were coprecipitating all of the spinel-assemblage phenocrysts before reaching the magma chamber. Clinopyroxene-assemblage magmas did not have picritic parents, but the compositions of phenocrysts suggest that they originated at about 9 kbars, near the transition between plagioclase peridotite and spinel peridotite in the mantle. Two glass groups have higher contents of alkalis, TiO2, and P2O5 than the others, evidently as a result of the compositions of mantle sources. Eruption of these lavas implies that conduits and chambers containing magmas from dissimilar sources were not completely interconnected on the Costa Rica Rift. The data are used to draw comparisons with the East Pacific Rise and to consider the mechanisms that may have prevented the eruption of ferrobasalts at these sites.