The pancreatic islet system of the rock bass /|nby Edward Francis Squires. -- 260 St. Catharines, Ont. : [s. n.],

The endocrine pancreas of the rock bass (Ambloplites rupestris) was examined by light and electron microscopy. Two cell types with staining properties similar to mammalian A and B cells, and a third, non-staining cell type were found in the spherical pancreatic islets that were surrounded by a connective tissue capsule and embedded in two small masses of exocrine tissue. From an analysis of the ultrastructure of the A and B cells, a secretory cycle for each of these cell types was proposed. The secretory cycle of the A cell consisted of three well defined stages: (1) A cell production stage: during which A granule formation occurred in the sacs of the Golgi apparatus and the cell was characterized by the presence of numerous secretory granules, some elements of lamellar endoplasmic reticulum, and a homogeneously granular nucleus. The cytoplasm contained few distended cisternae, variable numbers of free ribosomes, microtubules and small vesicles. (2) A cell release stage: during which the release of A granules occurred and the cell usually contained several large distended cisternae and variable numbers of secretory granules. Granule release mechanisms included exocytosis, by which individual granules were released into the extracellular space after their membranes fused with the plasmalemma, and emiocytosis, by which one or more granules were released into a large cisterna whose membrane fused with the plasmalemma and formed a pore through which the cisternal contents passed out of the cell. (3) A cell reorganization stage: during which the changeover from the release stage to the production stage occurred and the reorganization of organelles and membrane structures took place. The cell contained few secretory granules and numerous small endoplasmic reticular cisternae. The cytoplasm exhibited less electron density than either of the other two stages. The A granule after formation underwent a series of morphological changes which were described in four numerically identified phases. The secretory cycle of the B cell consisred of two stages: (1) B cell production stage: during which the B granule formation occurred in the sacs of the Go1gi apparatus. The cell was characterized by an irregular outline, the presence of numerous secretory granules, and an irregularly shaped nucleus which contained variable amounts of clumped chromatin. The cytoplasm contained moderate amounts of lamellar endoplasmic reticulum studded with ribosomes, several small vesicles, and an active Go1gi apparatus. (2) B cell release stage: during which the release of B granules occurred. The cell contained a rounded nucleus with dispersed chromatin, several distended endoplasmic reticular cisternae and a variable number of secretory granules. Granule release occu~ by emiocytosis and exocytosis similar to that found for the A cell.

A tour from the City of New-York, to Detroit, in the Michigan Territory, made between the 2d of May and the 22d of September, 1818 : the tour extends from New-York, by Albany, Schenectady, and Utica to Sacket's Harbor, and thence throught Lake Ontario, to St. Lawrence river, and down that stream to Hamilton village. Thence along both banks of the St. Lawrence, from Hamilton to the Thousand Islands; thence to Sacket's Harbor by water; from that place by the route of great Sodus, Geneva, Cananaigua and Batavia, to Buffalo; and from thence to Black Rock, Fort Erie, the Falls of Niagara, Queenston, Lewiston, and the memorable fields of Bridgewater and Chippewa after viewing the interesting place of Niagara, the author traversed the south shore of Lake Erie to the City of Detroit, and visited in the latter range, Dunkirk, Erie, Cleveland, Sandusky, and other places of less note. The tour is accompanied with a map upon which the route will be designated; a particular map of the Falls andRiver of Niagara, and the environs of the City of Detroit /

Errata slip inserted.

Reflections upon the late correspondence between Mr. Secretary Smith, and Francis James Jackson, esq., Minister Plenipotentiary of His Britannic Majesty /

Originally published in the Federal Republican of Baltimore.

Welland Canal Survey of Lands Philip Shaver 1829

Survey map and description of Philip Shaver's land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. Noteable features include; locks no. 16, 17, 18, 19, 20, ravine, corner stone, St. Catharines ditch, waste weir, concession line, barn. Surveyor notes are seen in pencil on the map. The deed for the land is dated October 1st, 1829.

Welland Canal Survey of Lands Francis Goring Parnell, 1826

Survey map and description of Francis Goring Parnell's land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. Noteable features include; line between Widow Secord and Parnell's land, line between Rykert and Parnell's land. The deed for the land is dated December 5th, 1826. The land totals 4 acres, 1 road, and 6 perches. Surveyor notes are seen in pencil on the map.

Welland Canal Survey of Lands Philip Carrol, 1830, 1846, n.d.

Survey map and description of Philip Carrol's land created by The Welland Canal Company. Included are three written descriptions of the lands along the Northern Reservoir, Southern Reservoir as well as the Canal and Reservoir with a drawing of the aforementioned lands. Noteable features for the Northern Reservoir include; line between Philip Carrol's land and Widow McAlpine's land. The land contains 9 acres, 2 roads and 24 perches of wood land. The survey is dated 1830. Noteable features for the Southern Reservoir include; Road to shorthills, side line North, and Watson's land. This survey is not dated. Noteable features for the Canal and Reservoir include; West line of lot, lot.213. The land contains 9 acres and 5 perches. The surveyor's updates for this survey are dated 1846. Surveyor notes are seen in pencil on the map.See also Pp 109-113

The Gleaner and Niagara Newspaper, January 1st, 1818

The Gleaner and Niagara Newspaper was a weekly paper in the town of Niagara-on-the-Lake that began publication December 4, 1817 and ceased in 1830. This bound volume has been divided by publication dates. Other dates included in the volume are: 1817 December 18 1817 December 25 1818 January 8 1818 January 15 1818 January 22 There is also a letter that was found inside the bound volume written by Andrew Heron on October 1 1817.

The Gleaner and Niagara Newspaper, January 8, 1818

The Gleaner and Niagara Newspaper was a weekly paper in the town of Niagara-on-the-Lake that began publication December 4, 1817 and ceased in 1830. This bound volume has been divided by publication dates. Other dates included in the volume are: 1817 December 18 1817 December 25 1818 January 1 1818 January 15 1818 January 22 There is also a letter that was found inside the bound volume written by Andrew Heron on October 1 1817.

The Gleaner and Niagara Newspaper, January 15, 1818

The Gleaner and Niagara Newspaper was a weekly paper in the town of Niagara-on-the-Lake that began publication December 4, 1817 and ceased in 1830. This bound volume has been divided by publication dates. Other dates included in the volume are: 1817 December 18 1817 December 25 1818 January 1 1818 January 8 1818 January 22 There is also a letter that was found inside the bound volume written by Andrew Heron on October 1 1817.

The Gleaner and Niagara Newspaper, January 22, 1818

The Gleaner and Niagara Newspaper was a weekly paper in the town of Niagara-on-the-Lake that began publication December 4, 1817 and ceased in 1830. This bound volume has been divided by publication dates. Other dates included in the volume are: 1817 December 18 1817 December 25 1818 January 1 1818 January 8 1818 January 15 There is also a letter that was found inside the bound volume written by Andrew Heron on October 1 1817.

Reflections upon the late correspondence between Mr. Secretary Smith, and Francis James Jackson, esq., Minister Plenipotentiary of His Britannic Majesty

Originally published in the Federal Republican of Baltimore. Printed by Benjamin Edes

Commemorative Medals of the War of 1812, 1963

In the original set, there were 10 medals with inventory numbers 1740-1749. This included Tecumseh, Chief of the Shawnees and construction in 1812 of Fort Prescott in Upper Niagara. These are not included in this collection. The Franklin Mint purchased the Wellings Mint in 1973.

Letter - Colonel Albert D. Shaw to Francis Lynde Stetson, 31 March 1892

A letter from Colonel Albert D. Shaw to Francis Lynde Stetson dated March 31, 1892. The letter is in regards to correspondence with the Attorney General in efforts to expedite the passing of an Act through Ontario Parliament. The act was introduced a week later (April 6, 1892) confirming the agreement between the Queen Vctoria Niagara Falls Park and the Canadian Niagara Power Company.