898 resultados para ES-SAGD. Óleo pesado. Fator de recuperação. Modelagem de reservatórios e simulação


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Pós-graduação em Ciência da Informação - FFC

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Dexamethasone (DEXA) is a synthetic glucocorticoid widely used in the handling of several drugs, for its proven benefits in fighting inflammation and allergies. Despite their benefits, their chronic use leads to several side effects that include changes in the body in the metabolism of carbohydrates, lipids and proteins. Moreover, being an anti-inflammatory, acts on the arachidonic acid pathway, reducing the expression of the enzyme cyclooxygenase (COX-2) and growth factor derived from the endothelium of blood vessels (VEGF) in various tissues. However, its effects on the myocardium are still uncertain. The physical training (PT), in turn, promotes effects contrary to those caused by chronic use of DEXA, however, little is known about the preventive effects of TF in the side effects of Dexa in the myocardium. Therefore, the aim of this study was to determine if the TF has the ability to prevent and/or mitigate the effects of Dexa in protein expression of COX-2 and VEGF in the myocardium. Forty animals were divided into 4 groups: sedentary control (SC), sedentary treated with Dexa (SD), trained control (TC) and Trained treated with Dexa (TD) and submitted to a protocol of physical training on the treadmill for 70 days (1 h/day-5 days per week, 60% of physical capacity) or kept sedentary. Over the past 10 days, rats were treated with Dexa (Decadron, 0.5 mg/kg per day, ip) or saline. During training the animals were weighed weekly and during treatment daily. At the end of treatment was made to measure fasting glucose levels of animals. The rats were killed with excess anesthesia and cardiac muscle was removed, weighed, homogenized, centrifuged and stored at -20° C for analysis of protein expression of VEGF and COX-2 by Western blotting technique. Treatment with dexamethasone caused a weight loss of 18% in sedentary animals and 13% in trained as well as elevated levels of fasting glucose in sedentary (88%). The TF was unable to mitigate the loss in...

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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The aim of this work was to evaluate the electrocardiography effects (ECG), sedation time and quality of recovery due to buprenorphine (G1) and butorphanol (G2) administration in dogs pretreated with acepromazine. Seven adult dogs were submitted to both protocols, with a thirty days interval between groups. G1 animals were premedicated with acepromazine (0.1 mg/kg) followed 10 minutes later with buprenorphine (0.005 mg/kg), both applied intravenously. The same procedure was performed for G2 employing butorphanol (0.3 mg/kg) instead of buprenorphine. The measurements of the variables heart rate (HR), duration and amplitude of P wave, P-R intervals (PR), QRS complex duration, R wave amplitude, Q-T intervals (QT) and R-R intervals (RR) were taken immediately before application of acepromazine (M0), 10 minute after administration of acepromazine (M10) and 10 minutes after opioids administration (M20). Serial measurements were carried out in 10 minute intervals after the administration of butorphanol or buprenorphine up to 60 minutes. Numeric data were submitted to Tukey Analysis (p < 0.05). The amplitude of P wave decreased 30 minutes after the administration of the butorphanol. Sedation time was longer in G1 (78 minutes) than G2 (72 minutes) and recovery was good in both groups. These results indicate that butorphanol or buprenorphine produced discreet alterations on ECG, which don´t contraindicate its clinical use.

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Pós-graduação em Agronomia (Horticultura) - FCA

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Matemática em Rede Nacional - IBILCE

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The aim of this paper was to evaluate the effect of retention and detention reservoirs along with the regulation in channel flow upgrade on flood for an urban watershed located at Rio Claro, SP. For this purpose, modeling and simulation techniques were applied for runoff determination and its propagation in channel. The Soil Conservation Service – SCS hydrologic model as well as Pulz and non-linear Muskingum-Cunge model were used. The software IPHS1 was applied on simulations. The results pointed out that the combination of retention increasing and detention reservoir implementation (120,000 m3, corresponding to 1.5% of the watershed area) with the streamflow upgrade (n decreasing from 0,04 to 0,02) can minimize the flood on the investigated Servidão watershed. Further, after the proposed intervention, the flood was eliminated for the investigated times of recurrence: 5, 20, 50 and 100 years. The prognostic indicated that the available area occupation had a minor effect on flow increasing due to the observed high urbanization.

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The objective of this research is to examine if the environmental management evolution is positively related towards the adoption of green supply chain management practices (GSCM) by companies in the electronics sector in Brazil. To reach this objective, a quantitative research was conducted by survey with 100 companies in the electronics sector in Brazil. The collected data were processed using descriptive statistics, Exploratory Factor Analysis and Structural Equation Modeling. The most important results are: in the sample, GSCM practices to the recovery of investment, as the resale of scrap and other waste materials, and the adequacy with legislation and auditing, obtained high scores; and research hypothesis (H1) was confirmed and considered statistically valid, indicating that, in fact, the evolution of environmental management influences the adoption of GSCM practices.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)