Pourquoi l'Allemagne a capitulé le 11 Novembre 1918; étude faite sur documents du G. Q. G. français.

At head of title: 10 Janvier 1919.

Worldwide radio noise levels expected in the frequency band 10 kilocycles to 100 megacycles

Bibliography: p. 13.

Policratici contenta, Restiuu[m] opus ... q[uo]d intitulat[ur] Policraticu[m] de nugis curialiu[m] et vestigiis philosopho[rum] Ioa[n]nis Salesberiensis ...

Mode of access: Internet.

Roberti Holkot natione Angli professione sacri predicatorum ordinis ... Oper? hoc in volumine contentorum catalogus : in quatuor libros Sententiarum questiones argutissime : quedam (vt ipse auctor appellat) c?ferentie : de imputabilitate peccati q?estio n? penitenda : determinationes item quar?d? aliar? q?stion? : tabula duplex omnium predictorum : auctoris ipsius vita nuper adiecta ...

Mode of access: Internet.

Gabrielis Biel ... Sacri canonis misse tam mystica q[uam] litteralis expositio : iami? summa cum dilegentia iterum atq[ue] iter? reuisa et correcta ...

CCBE S. XVI,

Q. Curtii Rufi De rebus gestis Alexandri Magni libri decem.

"Catalogus praecipuarum Q. Curtii Rufi editionum," [3] p. at the end.

Reports of cases in the reigns of Hen. VIII, Edw. VI, Q. Mary, and Q. Eliz. /

Mode of access: Internet.

Qānūnchah fī al-ṭibb, [880, i.e. 1475 or 1476].

Fine copy of al-Jaghmīnī's (d.1344) Qānūnchah, a compendium on medicine and an extract from Ibn Sīnā’s Qānūn. Brockelmann treats this author as distinct from an astronomer of the same name who died in 1221.

Three cases of Q fever osteomyelitis in children and a review of the literature

Q fever is a common zoonosis worldwide. Awareness of the disease and newer diagnostic modalities have resulted in increasing recognition of unusual manifestations. We report 3 cases of Q fever osteomyelitis in children and review the literature on 11 other reported cases. The cases demonstrate that Coxiella burnetii can cause granulomatous osteomyelitis that presents without systemic symptoms and frequently results in a chronic, relapsing, multifocal clinical course. Optimal selection and duration of antimicrobial therapy and methods of monitoring therapy are currently uncertain.

Unidirectional inversion of ibuprofen in Caco-2 cells: Developing a suitable model for presystemic chiral inversion study

Intestinal chiral inversion of ibuprofen is still lacking direct evidence. In a preliminary experiment, ibuprofen was found to undergo inversion in Caco-2 cells. This investigation was thus conducted to determine the characteristics and influence of some biochemical factors on the chiral inversion of ibuprofen in Caco-2 cells. The effects of substrate concentration (2.5-40 mu g/ml), cell density (0.5-2 x 10(6) cells/ well), content of serum (0-20%), coexistence of S ibuprofen (corresponding doses), sodium azide (10mm), exogenous Coenzyme A (CoA) (0.1 - 0.4 mm),. and palmitic acid (5-25 mu m) on inversion were examined. A stereoselective HPLC method based on the Chromasil-CHI-TBB column was developed for quantitative analysis of the drug in cell culture medium. The inversion ratio (F-i) and elimination rate constant were calculated as the indexes of inversion extent. Inversion of ibuprofen in Caeo-2 cells was found to be both dose and cell density dependent, indicating saturable characteristics. Addition of serum significantly inhibited the inversion, to an extent of 2.7 fold decrease at 20% content. Preexistence of S enantiomer exerted a significant inhibitory effect (p < 0.01 for all tests). Sodium azide decreased the inversion ratio from 0.43 to 0.32 (p < 0.01). Exogenous CoA and palmitic acid significantly promoted the inversion at all tested doses (p < 0.01 for all tests). This research provided strong evidence to the capacity and capability of intestinal chiral inversion. Although long incubation times up to 120 h were required, Caco-2 cells should be a suitable model for chiral inversion research of 2-APAs considering the human-resourced and well-defined characteristics from the present study.