999 resultados para Ammon, Christoph Friedrich von, 1761-1849.
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Französische Zusammenfassungen der Artikel im Ausstellungskatalog "Der Weltensammler"
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Friedrich von Oppeln-Bronikowski
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BackgroundThe present preliminary study describes concentration time courses of the NSAID carprofen in the plasma and synovial fluid in a microfrature sheep model after transcutaneous treatments with a novel application device (Vetdrop®). To treat circumscribed inflammatory processes a transcutaneous application device could potentially be beneficial. After transcutaneous application normally lower systemic concentrations are measured which may reduce the incidence of side effects, whereas efficacy is still maintained.In this study carprofen was used based on its capacity to provide analgesia after orthopaedic procedures in sheep and it is considered that it may have a positive influence on the healing of cartilage in low concentrations.ResultsIn all transcutaneously treated animals, carprofen plasma concentrations exceeded those of synovial fluid, although plasma levels remained significantly reduced (300-fold) as compared to carprofen administered intravenously. Furthermore, in contrast to the intravenously treated animals, a modest accumulation of carprofen in plasma and synovial fluid was observed in the transcutaneously treated animals over the 6-week treatment period.ConclusionsThe transcutaneously administered carprofen using the Vetdrop® device penetrated the skin and both, plasma- and synovial concentrations could be measured repeatedly over time. This novel device may be considered a valuable transcutaneous drug delivery system.
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von Ludwig Christoph Schefer
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abweichender Titel des beigefügten Werkes: Nachrichten von den heiligen Büchern der Synagoge zu Cai-fong-fu, der Hauptstadt der Provinz Ho-nan
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von M. E. Stern
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In Fraktur
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In Fraktur
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von Friedrich Stoltze
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von Friedrich Hart
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Welsch (Projektbearbeiter): Aufruf (in Gedichtform) zur Einheit anläßlich des Todes des Generals Friedrich von Gagern im Gefecht mit den Freischaren Heckers am 20. April 1848 bei Kandern (Markgräflerland)