An ent-Kaurane Diterpene from Euphorbia wallichii

One known ent- kaurane diterpene, ent- 16α, 17- dihydroxykauran- 3-one, were isolated from the roots of Euphorbia wallichii for the first time. Its structure was elucidated on the basis of spectral methods. And the NMR assignments of the compound in CD3OD were given for the first time.

A new daphnane diterpene from Daphne tangutica

A new daphnane diterpene was isolated from the root barks of Daphne tangutica Maxim. Its structure was elucidated as 1, 2 alpha-dihydro-20-palimoyldaphnetoxin by the spectroscopic evidence including 2D-NMR.

A new guaiane diterpenoid from Euphorbia wallichi

A new guaiane-type diterpenoid, (1 alpha, 5 alpha, 7 alpha)-3,10(18), 11-dictytriene-19-acid, was obtained from the roots of Euphorbia wallichii. This is the first isolation of guaiane diterpene from this genus of Euphorbia. The structure was elucidated by spectral methods. And the compound was tested for the cytotoxicities on the cancer cell line P-388 and A-549 in vitro.

黄土中主要温室气体组分特征

Scientists have paid much attention to the greenhouse effects and the greenhouse gases for the fact of global warming. There are many uncertainties in the prediction of future climatic change. One of the important reasons causing the uncertainties is insufficient researches of the sources and sinks of greenhouse gases, especially, there is a missing sink in the global carbon cycle. The recent researches proposal that there may be an important carbon sink in the middle-latitude terrestrial ecosystems (vegetation and soil) in the North Hemisphere, despite that there is much disputation about its position and amplitude. Chinese loess is located in the middle latitude area in the North Hemisphere, what kind of role does it play in and how does it influence on the balance of the global greenhouse gases budget? For this reason, many samples were taken and analyzed from wide range and multi-stratum of Chinese loess to understand characteristics of major greenhouse gases in loess and loess possible effect on global greenhouse gas budget. Using self-made spiral corer, we totally took 81 gas samples and 65 soil samples from 7 loess profiles in China such as Zhaitang loess section of Beijing, Pianguan, Xingxian, Lishi, Puxian, Jishan loess section of Shanxi Province, and Luochuan loess section of Shaanxi Province. The gas concentrations for CO_2, CH_4 and N_2O, the contents of N_2, O_2 and carbonate, and the carbon isotopic compositions of CO_2 and carbonate in loess strata sequences are observed and measured. In addition, 19 gas samples data of the Weinan loess section, Shaanxi Province are combination with this research to study characteristics of greenhouse gases in loess. This research indicates that (1) the free gases in loess are neither paleo-atmospheric gases nor modern atmospheric gases; (2) the concentrations of CO_2, CH_4 and N_2O in loess are higher than atmospheric level; (3) the δ~(13)C of loess CO_2 shows that the CO_2 in loess mainly comes from the oxygenolysis of organic matters, but because of isotopic exchange with carbonate in loess, the carbon isotopic exchange with carbonate in loess, the carbon isotopic compositions of loess CO_2 are much more heavier than organic original CO_2; (4) the concentration of CH_4 in Malan loess is lower because it is not favorable for the decomposition of anaerobic bacteria in the Malan Loess; (5) estimation of the total amount of the carbonate in loess reveals that loess is a huge carbon reservoir (about 850PgC). In addition, the impact of the deuterogenic carbonatization during the loess accumulation on the global carbon cycle was discussed, and the preliminary conclusion is that the research work is still not enough to evaluate the effect of loess on the sources and sinks of the anthropogenic CO_2.

PRINCIPAIS INDICADORES: AGRÍCOLAS, v. 3, n. 19, 2010.

2010

PRINCIPAIS INDICADORES: LEITE E DERIVADOS, v. 3, n. 19, 2010.

2010

PRINCIPAIS INDICADORES: MACROECONÔMICOS, v. 3, n. 19, 2010.

2010

Custo médio de produção de suínos para abate: anexo 19 - março/85.

1985

BOAS PRÁTICAS agrícolas para produção de cupuaçuzeiro - programa 19.

2009

Programa Nacional de Joyería. Taller de Diseño, Departamento de Antioquia municipios de Frontino y Santa Fe de Antioquia febrero 19 a marzo 17 de 2002.

107 hojas : Ilustraciones.

Friendly Virtual Machine: Leveraging a Feedback-Control Model for Application Adaptation

With the increased use of "Virtual Machines" (VMs) as vehicles that isolate applications running on the same host, it is necessary to devise techniques that enable multiple VMs to share underlying resources both fairly and efficiently. To that end, one common approach is to deploy complex resource management techniques in the hosting infrastructure. Alternately, in this paper, we advocate the use of self-adaptation in the VMs themselves based on feedback about resource usage and availability. Consequently, we define a "Friendly" VM (FVM) to be a virtual machine that adjusts its demand for system resources, so that they are both efficiently and fairly allocated to competing FVMs. Such properties are ensured using one of many provably convergent control rules, such as AIMD. By adopting this distributed application-based approach to resource management, it is not necessary to make assumptions about the underlying resources nor about the requirements of FVMs competing for these resources. To demonstrate the elegance and simplicity of our approach, we present a prototype implementation of our FVM framework in User-Mode Linux (UML)-an implementation that consists of less than 500 lines of code changes to UML. We present an analytic, control-theoretic model of FVM adaptation, which establishes convergence and fairness properties. These properties are also backed up with experimental results using our prototype FVM implementation.

Resolved Torsional Splittings in the ν18 and ν19- Bands of Propene

info:eu-repo/semantics/published

Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance.

Release of endogenous dynorphin opioids within the spinal cord after partial sciatic nerve ligation (pSNL) is known to contribute to the neuropathic pain processes. Using a phosphoselective antibody [kappa opioid receptor (KOR-P)] able to detect the serine 369 phosphorylated form of the KOR, we determined possible sites of dynorphin action within the spinal cord after pSNL. KOR-P immunoreactivity (IR) was markedly increased in the L4-L5 spinal dorsal horn of wild-type C57BL/6 mice (7-21 d) after lesion, but not in mice pretreated with the KOR antagonist nor-binaltorphimine (norBNI). In addition, knock-out mice lacking prodynorphin, KOR, or G-protein receptor kinase 3 (GRK3) did not show significant increases in KOR-P IR after pSNL. KOR-P IR was colocalized in both GABAergic neurons and GFAP-positive astrocytes in both ipsilateral and contralateral spinal dorsal horn. Consistent with sustained opioid release, KOR knock-out mice developed significantly increased tactile allodynia and thermal hyperalgesia in both the early (first week) and late (third week) interval after lesion. Similarly, mice pretreated with norBNI showed enhanced hyperalgesia and allodynia during the 3 weeks after pSNL. Because sustained activation of opioid receptors might induce tolerance, we measured the antinociceptive effect of the kappa agonist U50,488 using radiant heat applied to the ipsilateral hindpaw, and we found that agonist potency was significantly decreased 7 d after pSNL. In contrast, neither prodynorphin nor GRK3 knock-out mice showed U50,488 tolerance after pSNL. These findings suggest that pSNL induced a sustained release of endogenous prodynorphin-derived opioid peptides that activated an anti-nociceptive KOR system in mouse spinal cord. Thus, endogenous dynorphin had both pronociceptive and antinociceptive actions after nerve injury and induced GRK3-mediated opioid tolerance.

Imátgenes 19, 20 y 21

Por quinta vez puso cuatro motas de tinta en el papel, les puso nombres (A, B, C, D) y los unió con segmentos para formar un cuadrilátero. Luego señaló los puntos medios de sus cuatro lados y los conectó formando otro cuadrilátero (P, Q, R, S). Ahí estaba el problema. Ese cuadrilátero interior siempre resultaba ser un paralelogramo pusiera como pusiera los cuatro puntos originales. ¿Acaso había orden en el caos? Por un momento pensó que quizá había truco, que tal vez sucedía así porque la gente ponía los puntos de formas similares. Pero ya había probado configuraciones muy raras, incluso dejó que los segmentos del cuadrilátero ABCD se interceptasen, y siempre obtenía idéntico resultado. No, lo que parece cumplirse para cualquier caso no es ningún truco, sino un teorema que demostrar.