The Iowa African-American Journal, July 1999, Vol. 5, no. 3

Newsletter for the Iowa Commission on the Status of African-Americans

Iowa Community Empowerment Newsletter, June 2004, Vol. 5, no. 3

Monthly newsletter for the Iowa Department of Public Health

Impaired activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 in cultured preadipocyte-derived adipocytes and myotubes of obese subjects.

Insulin resistance in obesity is partly due to diminished glucose transport in myocytes and adipocytes, but underlying mechanisms are uncertain. Insulin-stimulated glucose transport requires activation of phosphatidylinositol (PI) 3-kinase (3K), operating downstream of insulin receptor substrate-1. PI3K stimulates glucose transport through increases in PI-3,4,5-(PO(4))(3) (PIP(3)), which activates atypical protein kinase C (aPKC) and protein kinase B (PKB/Akt). However, previous studies suggest that activation of aPKC, but not PKB, is impaired in intact muscles and cultured myocytes of obese subjects. Presently, we examined insulin activation of glucose transport and signaling factors in cultured adipocytes derived from preadipocytes harvested during elective liposuction in lean and obese women. Relative to adipocytes of lean women, insulin-stimulated [(3)H]2-deoxyglucose uptake and activation of insulin receptor substrate-1/PI3K and aPKCs, but not PKB, were diminished in adipocytes of obese women. Additionally, the direct activation of aPKCs by PIP(3) in vitro was diminished in aPKCs isolated from adipocytes of obese women. Similar impairment in aPKC activation by PIP(3) was observed in cultured myocytes of obese glucose-intolerant subjects. These findings suggest the presence of defects in PI3K and aPKC activation that persist in cultured cells and limit insulin-stimulated glucose transport in adipocytes and myocytes of obese subjects.

State Library Update, July 2007, Vol.5, no. 3

Quarterly State Library Update for patrons.

VIP Connection, August 2005, Vol. 5, no. 3

Iowa Lottery newsletter for members of the Iowa Lottery VIP Club.

Customer Focus Newsletter, May/June, 2008, Vol. 5, no. 3

A bi-monthly bulletin to keep the department/agency management teams of state government better informed. We hope to consolidate most of the service update messages we send throughout the month and keep you updated about the work of the Customer Councils. If yours is one of the many departments who participated in the second annual DAS customer satisfaction survey recently, we thank you for taking the time to give us this important feedback. We look forward to sharing survey results with you, and pledge to consider responses carefully as we work to determine benchmarks and set future priorities.

Innovative Outstanding Weatherization Assistance News July 2007, Vol. 5, no. 3

This is a quarterly newsletter for the Iowa Weatherization Program. The purpose of the newsletter is to share with you information on all aspects of the program as well as spotlight a couple of agencies in each issue. We will provide information on upcoming events, training schedules, monitoring schedules and general news about the program. There will be a section of questions we have received from you and the answers provided.

Secure and Prepared Newsletter, February 5, 2009, Vol. 5, no. 3

A bi-weekly newsletter for those involved in the fields of homeland security and/or emergency management

Healthy Aging Update, April 2, 2010, Vol. 5, no. 3

This bimonthly electronic newsletter will provide information and resources on nutrition and health promotion and disease prevention. The Healthy Aging Update is produced for informal and educational purposes only. The newsletter will be distributed electronically and posted on the Department’s website at www.state.ia.us/elderaffairs.

Iowa Agri-News, December 7, 2011, Vol. 11, no. 20

Crop and livestock summaries for the state of Iowa, produced by the Iowa Department of Agriculture. Older Title: Agri-News.

Lottery Action, May 19-June 1, 2014, Vol. 20, No. 9

Iowa Lottery Retailer Newsletter

Iowa Ag Review, Summer 1999, Vol. 5, no. 3

Iowa Ag Review is a quarterly newsletter published by the Center for Agricultural and Rural Development (CARD). This publication presents summarized results that emphasize the implications of ongoing agricultural policy analysis, analysis of the near-term agricultural situation, and discussion of agricultural policies currently under consideration.

Iowa Manure Matters: Odor and Nutrient Management, Fall 2002, Vol. 5, no. 3

Iowa Manure Matters: Odor and Nutrient Management is published by Iowa State University Extension, with funding support from the USDA Natural Resource Conservation Service.

Community College Leader Bulletin, Fall 2015, Vol. 5, Issue 3

Newsletter produced by the Iowa Department of Education, Community College unit. This report has information about staff, grants, statistical data, requirements and more.