Promotion of hepatocarcinogenesis by hexachlorobenzene in energy-restricted rats

The interaction between dietary energy restriction and low dose of the fungicide hexachlorobenzene (HCB) was evaluated in a rat liver medium-term bioassay for carcinogenesis. Male Wistar rats were fed a control or a 50% energy-restricted diet, both added or not with 50 ppm HCB, for 6 weeks. HCB exposure or energy restriction separately did not exert any influence on the development of glutathione S-transferase placental form (GST-P+) foci of hepatocytes. Simultaneous HCB exposure and energy restriction induced a significant increase in liver centrilobular hypertrophy and GST-P+ foci development. Our findings suggest that energy restriction increases liver response to low dose of HCB, unmasking the promoting potential of this fungicide. (C) 2000 Elsevier B.V. Ireland Ltd. All rights reserved.

Metalloproteinases 2 and-9 activity during promotion and progression stages of rat liver carcinogenesis

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Mexico: export promotion policies on the cutting edge

Includes bibliography

Colombia: regaining the upper hand in export promotion

Includes bibliography

E-commerce and export promotion policies for small- and medium-sized enterprises: East Asian and Latin American experiences

Includes bibliography

E-commerce environment and trade promotion for Latin America: policy implications from East Asian and advanced economies' experiences

Includes bibliography

Export promotion policies in CARICOM: main issues, effects and implications

Includes bibliography

Trade and investment promotion between Asia-Pacific and Latin America: present position and future prospects

Includes bibliography

Is the Czech economy a success story?: the case of CzechInvest, the strategic promotion agency in Czech industrial restructuring

Includes Bibliography

First Europe-Latin America Dialogue on Promotion of Energy Efficiency

Includes bibliography

Fomento de las exportaciones en el Japón y la aplicación de esa experiencia en América Latina = Export promotion in Japan and its application to Latin America

Incluye Bibliografía

La transferencia de tecnología y su relación con la política comercial y el fomento de las exportaciones de América Latina = The transfer of technology and its relation to trade policy and export promotion in Latin America

Incluye Bibliografía