982 resultados para Promotor Oct-4


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[I] 1884/5. (Contrib. no. 20) 1885. Repub. from Bulletin no. 32, Oct., 1885.--[II] 1885/86. (Contrib. no. 24) 1887. Repub. from Bulletin no. 36, 1887.--III. 1887. (Contrib. no. 29) 1888. Repub. from Bulletin no. 39, 1888.--IV. 1890. (Contrib. no. 40) 1891. Repub. from Bulletin no. 48, 1891.

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Trägerband: 'E. lin. 4. N. 5'; Vorbesitzer: Karmeliterkloster Frankfurt am Main

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Trägerband: Ms. lat. oct. 26; Ms. lat. oct. 30; Vorbesitzer: Johann Hartmann Beyer

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The objective of the final artcile in this series is to describe how recent developments in genetics are likely to imact the diagnosis, scientific understanding, and future treatment of ocular disease.

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Trägerbände: Inc. oct. 464 Bd. 2; Inc. oct. 464 Bd. 4; Ms. Praed. 153; ein Band mit unbekannter Signatur; Vorbesitzer: Dominikanerkloster Frankfurt am Main

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PURPOSE: To assess and describe sequential morphological changes in the choroidal neovascularization (CNV) net using optical coherence tomography angiography (OCTA) in patients undergoing treatment with intravitreal antivascular endothelial growth factor (VEGF). METHODS: Prospective cohort study. OCTA was performed sequentially: before (t0), 1 h (t1), 1 week (t2) and 1 month after the injection (t3), using Avanti RTVue XR equipped with the AngioVue® software (Optovue, Calif., USA). All images were classified by two independent graders. RESULTS: Ten eyes of 10 patients, with a mean age of 72.4 ± 10.5 years, were included. CNV morphology was described as tree-like in 5 eyes, glomerular in 1 and fragmented in 4. A fibrovascular capsule surrounding the CNV net was found in 4 eyes and a feeder trunk was noticed in 6. No changes were observed at t1. Loss of peripheral capillaries, vessel fragmentation and decreased vessel density were evident in 8 eyes at t2. The CNV capillary density and the peripheral anastomosis increased in all of these at t3. Two eyes remained unchanged through the whole length of follow-up. CONCLUSIONS: Significant changes in the CNV net can be observable in OCTA at least 1 week after intravitreal anti-VEGF. The safety of frequent examinations may provide a method of gauging treatment effects.

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PURPOSE: To assess and describe sequential morphological changes in the choroidal neovascularization (CNV) net using optical coherence tomography angiography (OCTA) in patients undergoing treatment with intravitreal antivascular endothelial growth factor (VEGF). METHODS: Prospective cohort study. OCTA was performed sequentially: before (t0), 1 h (t1), 1 week (t2) and 1 month after the injection (t3), using Avanti RTVue XR equipped with the AngioVue® software (Optovue, Calif., USA). All images were classified by two independent graders. RESULTS: Ten eyes of 10 patients, with a mean age of 72.4 ± 10.5 years, were included. CNV morphology was described as tree-like in 5 eyes, glomerular in 1 and fragmented in 4. A fibrovascular capsule surrounding the CNV net was found in 4 eyes and a feeder trunk was noticed in 6. No changes were observed at t1. Loss of peripheral capillaries, vessel fragmentation and decreased vessel density were evident in 8 eyes at t2. The CNV capillary density and the peripheral anastomosis increased in all of these at t3. Two eyes remained unchanged through the whole length of follow-up. CONCLUSIONS: Significant changes in the CNV net can be observable in OCTA at least 1 week after intravitreal anti-VEGF. The safety of frequent examinations may provide a method of gauging treatment effects.