ESMO consensus guidelines for the management of patients with metastatic colorectal cancer

Colorectal cancer (CRC) is one of the most common malignancies in Western countries. Over the last 20 years, and the last decade in particular, the clinical outcome for patients with metastatic CRC (mCRC) has improved greatly due not only to an increase in the number of patients being referred for and undergoing surgical resection of their localised metastatic disease but also to a more strategic approach to the delivery of systemic therapy and an expansion in the use of ablative techniques. This reflects the increase in the number of patients that are being managed within a multidisciplinary team environment and specialist cancer centres, and the emergence over the same time period not only of improved imaging techniques but also prognostic and predictive molecular markers. Treatment decisions for patients with mCRC must be evidence-based. Thus, these ESMO consensus guidelines have been developed based on the current available evidence to provide a series of evidence-based recommendations to assist in the treatment and management of patients with mCRC in this rapidly evolving treatment setting.

University of Michigan Field Hockey Team, 1992

Front Row: Mary Beth Bird, Katie Allison, Katie Thomas, Katie Vignevic

Middle Row: Rachael Geisthardt, Kalli Hose, Nancy Irvine, Chrissie Johnson Shay Perry, Lelli Hose, Keely Libby, Jen DiMascio, Nicole Hoover

Back Row: assistant coach Meri Dembrow, Jennifer Foley, Aaleya Koreishi, Gia Biagi, Sherene Smith, Jennifer Lupinsiki, Selina Harris, Meredith Franden, Heather Rooney, student athletic trainer Bryn Mickel, head coach Patti Smith

UM Women's Soccer Team, 1996

First Row: Michele Brach, Debbie Flaherty.

Second Row: Ashley Marks, Amanda Gauthier, Stephanie McArdle, Alana Peters, Laura Fedrigo, Amber Berendowski, Karen Montgomery, Jaime Ross, Carrie Brady, Vanessa Lewis, Bethany Greenblatt, Jessica Limauro, Assistant Coach Scott Forrester.

Third Row: Trainer Ann Lighthill, Trainer Rex Thompson, Kristin Buckley, Kjersten Kuhlman, Kelly Lukasik, Mari Hoff, Emily Schmitt, Luren Glister, Jori Welchans, Jessica Jones, Marie Spaccarotella, Jen Stahl, Nicole Savage, Shannon Poole, Ruth Poulin, Assistant Coach Pete Kowall, Head Coach Debbie Belkin.

Reisenovellen.

Mode of access: Internet.

Flue-cured tobacco, mechanization and labor : impacts of alternative production levels /

Mode of access: Internet.

Philippi a Limborch De veritate religionis Christianæ : amica collatio cum erudito Judæo.

"Urielis Acosta Exemplar humanae vitae": p. [651]-692.

An alphabetical digest of the public statute law of South-Carolina,

"The two first volumes contain all the English statutes and acts of Assembly of a general permanent nature ... also the constitutions of the state, and of the United States, together with such acts of the Congress of the United States, now in force, as more immediately concern the people ... of the state. These laws are digested under various heads or titles, and arranged alphabetically ... The third volume contains, under various titles, in alphabetical order, all the acts of Assembly, now of force, not contained in the two first volumes, being of a less general and permanent nature."--Introd.

The message of the Book of Revelation,

Mode of access: Internet.

The pseudoscorpions of Illinois /

"Literature cited": p. 494-496.

Die Gesetze des chemischen gleich Gewichtes für den verdünnten, gasförmigen oder gelösten Zustand.

First published in French in Kongl. Svenska vetenskapsakademiens Handlingar. bd. 21, no. 17, 1886. Presented Oct. 14, 1885.

Aquarelle aus dem Leben.

Theil 5-6. Neue Aquarelle aus dem Leben. Th. 1-2. Stuttgart, 1840.

Det kongelige Sundhedskollegiums forhandlinger i aaret...

Mode of access: Internet.