The PPARalpha-leukotriene B4 pathway to inflammation control.

Inflammation is a local immune response to 'foreign' molecules, infection and injury. Leukotriene B4, a potent chemotactic agent that initiates, coordinates, sustains and amplifies the inflammatory response, is shown to be an activating ligand for the transcription factor PPARalpha. Because PPARalpha regulates the oxidative degradation of fatty acids and their derivatives, like this lipid mediator, a feedback mechanism is proposed that controls the duration of an inflammatory response and the clearance of leukotriene B4 in the liver. Thus PPARalpha offers a new route to the development of anti- or pro-inflammatory reagents.

La formació en primers auxilis psicològics i emergències en el títol de grau en psicologia

En el nou marc universitari que dibuixa l’adaptació de les titulacions a l’Espai Europeud’Educació Superior, es proposa que el titulat de grau en Psicologia acabi la carrera amb lescompetències bàsiques mínimes d’ajut psicològic que li permetin fer front a situacionsd’emergència inesperades i reaccionar de manera professional sense empitjorar la situació operjudicar l’estat de les víctimes, i amb un mínim de seguretat en allò què ha de fer o, al menys,en allò que no ha de fer. Es considera que hauria de tenir, com a mínim, el mateix nivell deformació que tenen altres col·lectius que habitualment es troben implicats en una emergència(personal sanitari, bombers, voluntaris, etc.) per tal que no es trobi en inferioritat de condicionspel que es refereix a la manera de proporcionar primers auxilis psicològics a víctimes. Esproposa un programa formatiu en el títol de grau en Psicologia

La producció catalana de fonts d'informació electrònica sobre dret: estat de la qüestió

L'article identifica i descriu les fonts d'informació electrònica sobre dret produïdes a Catalunya, i les produïdes fora del nostre país, que, en la major part del seu contingut, fan referència al dret de Catalunya. Es tracten les fonts d'informació d'interésper a la globalitat del dret ¿publicacions de documents parlamentaris, repertoris de legislació i jurisprudència, publicacions doctrinals i obres de referència¿ i per a cada una de les seves branques o especialitats, així com una sèrie de nous recursos desenvolupats a la xarxa Internet i d'interés per al dret.

La investigacion cualitativa y sus aplicaciones en Biblioteconomia y Documentacion

Se intenta determinar cuáles son las técnicas cualitativas concretas que pueden ser útiles en el desarrollo de investigaciones en Biblioteconomía y Documentación, qué temas son más susceptibles de ser abordados desde una óptica cualitativa, y si existe una correlación entre la técnica empleada y el tema tratado. Se analiza la temática y técnicas empleadas en los artículos de investigación publicados en Journal of the American Society for Information Science entre 1995 y 1997, y en los aparecidos en Journal of Documentation y Library and Information Science Research desde 1993 hasta 1997. La mayor parte de los artículos que emplean técnicas cualitativas estudian el comportamiento del usuario en la recuperación de la información, bien sea explorando su conducta al utilizar un sistema automatizado, o bien centrándose en las tácticas que diversos grupos de usuarios emplean al resolver sus necesidades informativas. Finalmente se exponen las principales características que definen este tipo de investigaciones.

Iowa Problem Identification, February 2010

Each year, traffic crashes in the United States result in nearly 300,000 deaths and serious injuries. In 2008 alone, traffic crashes cost the nation an estimated $230 billion, nine times more than the estimated cost of all crime. Highway crashes represent the leading cause of death and disabling injury for persons under age 35. In recognition of this problem, the Congress of the United States enacted national highway safety legislation in 1966, which led to the establishment of the National Highway Traffic Safety Administration (NHTSA). The legislation also provided for federal highway safety monies to be made available to the states with a goal of reducing death and injury on the nation’s roads. Iowa has been very active in the federal-state local highway safety partnership since the mid 1960s.

Iowa's Blueprint for Safety,

To identify traffic safety problems and thereon develop and implement traffic safety programs designed to reduce death and injury on Iowa’s streets and highways through partnerships with local, county, state and private sector agencies.

Project Newsletter Iowa Public Health Tracking, June 2013

The Data Warehouse Replacement Project includes updated County Health Snapshot reports. The snapshots provide an overview of key health indicators for local communities. They contain county-level measures that are organized into eight categories. The categories are asthma, cancer, health behaviors and outcomes, heart disease and other chronic conditions, infectious disease, mortality and injury prevention, population statistics and reproductive outcomes. The updated county health snapshots include almost forty new chronic disease indicators in addition to all of the indicators in the existing snapshots.There will be two different reports available in the Data Warehouse replacement system. One of the reports is a multi-year county health snapshot. This report has a similar format to the previous county health snapshot report in the current Data Warehouse. It will display multiple years of data for a single county. The data will be for the most current year available and the two years prior. The state values for the current year will also be included.

An extraordinary case of an intracranial foreign body after a gunshot to the head.

Intermediate targets (IT) can modify the morphology of an entrance wound, the trajectory of the bullet, and contaminate the path with fragments or material from the target. The penetration into the body of big fragments or even of an entire IT is exceptional and only rarely reported in the literature. The interpretation of a gunshot wound after contact of the bullet with IT can sometimes be very tricky as the classical morphology can be missing. The presented case is a rare example of atypical entrance wound and path due to a surprising intermediate target of a gunshot fired against the head.

Iowa Historic Property Study of the Zeman Barn, 2009

The Zeman Barn (86-00028) is an early twentieth-century example of a gothic roofed barn and is part of the Zeman Farmstead located along U.S. Highway 30 in Otter Creek Township (Township 38N, Range 14W), Tama County, Iowa (Figures 1 and 2). The farmstead was initially evaluated in a reconnaissance architectural survey conducted in 1998 by The Louis Berger Group, Inc (Berger). An intensive architectural survey of the property by Berger’s Principal Architectural Historian, Martha H. Bowers, evaluated the farmstead as not being eligible for listing in the National Register of Historic Places (National Register) but noted that the barn appears to be eligible for listing in the National Register under Criterion C (Bowers 1998). At the request of the Iowa Department of Transportation, Berger completed the recordation project to provide a documentary record of the Zeman Barn in accordance with the guidelines set forth by the Iowa State Historic Preservation Office regarding historic property studies for barns. Background research for this project was conducted in September 2008 and April 2009. The property was inspected and photographed in May 2008. Information on the property was gathered through background research, interviews with Zeman family members, field investigation, and photo documentation. Historical maps of the project area were used to collect data necessary for developing regional and local historic contexts. The research for this report was conducted at the Tama County Courthouse and the Tama County Historical Museum Genealogical Library, both in Toledo. Much of the background research for the project was conducted by Camilla Deiber and Michael Dulle. Ms. Deiber also prepared the photographic documentation, plan drawings, and the graphics used in this report. Mr. Roger L. Ciuffo conducted interviews with Zeman family members and wrote this report.

Le bon vin d’Orleans, le punays lac de Sorbone et la mode de Bretaigne: sociocentrisme lúdic i ambivalència als blasons populars del Pantagruel de Rabelais, amb mostres de versions en diferents llengües

En aquest article es presenta una selecció d’un corpus extret del Pantagruel, en el qual els personatges de Rabelais ataquen o afalaguen, grotescament i hiperbòlica, en el més pur estil pantagruèlic, les altres nacions o viles. Per a aquests epítets ètnics, Rabelais reutilitza el blasó popular (blason populaire), en una fusió total de la lloança i la injúria. En el nostre treball comprovarem si la visió sociocèntrica que el blasonador aplica al blasonat, així com el propòsit lúdic, han aconseguit ser traslladats a les versions catalana (Miquel-Àngel Sánchez Férriz, 1985), espanyola (Alicia Yllera, 2003), italiana (Mario Bonfantini, 1953) i anglesa (Burton Raffel, 1991).

Iowa Historic Property Study: Iowana Farms Milk Company, 1416 State Street, City of Bettendorf, Scott County, Iowa, 2012

The Iowana Farms Milk Company factory building was considered to retain sufficient integrity and possess sufficient significance to be considered eligible for the National Register of Historic Places under Criteria A and C for its historical and architectural significance in the Bettendorf community. The Iowana Farms Milk Company was an important early to mid-twentieth-century business in Bettendorf, and was among the few that was not owned or operated by the Bettendorf Company. It was a strong and thriving business for many years, and its products were well known in the Quad Cities region. The importance of this property becomes even more significant when one considers that most of the buildings once associated with the actual Bettendorf Company, which was undeniably the most important business and industry in town, are now gone. As a result, the Iowana Farms Milk Company factory building was a physical vestige of the once-thriving commercial industries that made Bettendorf into a city in the twentieth century. This property was further significant for its representation of the evolution of the dairy industry in the twentieth century from farm to factory production. It also reflected the changes to the industry based on scientific discoveries, mechanical innovations, and governmental regulations related to improved sanitation and the pure milk movement. The Iowana Farms Milk Company represented a model plant for the time, and the marketing strategies it employed followed the trends of the industry. The Iowana Farms Milk Company plant had to be removed to make room for a new I-74 bridge over the Mississippi River at Bettendorf. The construction of the new bridge also required removal of the historic Iowa-Illinois Memorial Bridge. The documentation reported herein and for that of the Iowa-Illinois Memorial Bridge fulfills the requirements of the Memorandum of Agreement regarding the removal of these historic properties.

La douleur prolongée chez le nouveau-né: étude de cas [Prolonged pain in neonates: retrospective analysis].

INTRODUCTION: infants hospitalised in neonatology are inevitably exposed to pain repeatedly. Premature infants are particularly vulnerable, because they are hypersensitive to pain and demonstrate diminished behavioural responses to pain. They are therefore at risk of developing short and long-term complications if pain remains untreated. CONTEXT: compared to acute pain, there is limited evidence in the literature on prolonged pain in infants. However, the prevalence is reported between 20 and 40 %. OBJECTIVE : this single case study aimed to identify the bio-contextual characteristics of neonates who experienced prolonged pain. METHODS : this study was carried out in the neonatal unit of a tertiary referral centre in Western Switzerland. A retrospective data analysis of seven infants' profile, who experienced prolonged pain ,was performed using five different data sources. RESULTS : the mean gestational age of the seven infants was 32weeks. The main diagnosis included prematurity and respiratory distress syndrome. The total observations (N=55) showed that the participants had in average 21.8 (SD 6.9) painful procedures that were estimated to be of moderate to severe intensity each day. Out of the 164 recorded pain scores (2.9 pain assessment/day/infant), 14.6 % confirmed acute pain. Out of those experiencing acute pain, analgesia was given in 16.6 % of them and 79.1 % received no analgesia. CONCLUSION: this study highlighted the difficulty in managing pain in neonates who are exposed to numerous painful procedures. Pain in this population remains underevaluated and as a result undertreated.Results of this study showed that nursing documentation related to pain assessment is not systematic.Regular assessment and documentation of acute and prolonged pain are recommended. This could be achieved with clear guidelines on the Assessment Intervention Reassessment (AIR) cyclewith validated measures adapted to neonates. The adequacy of pain assessment is a pre-requisite for appropriate pain relief in neonates.

Watershed Planning Advisory Council Annual Report January 2015

This report provides updates on the WPAC recommendations made in its 2013 legislative report, including actions taken on those recommendations and any follow-up recommendations from WPAC. Recommendations include documentation of activities, and the needs and challenges toward making progress in protecting Iowa’s water resources, identified by WPAC in coordination with all agencies and stakeholders in the management of the state’s water resources in a sustainable, fiscally responsible, and environmentally conscientious manner.

Watershed Planning Advisory Council Annual Report July 2013

This report provides updates on the WPAC recommendations made in its 2013 legislative report, including actions taken on those recommendations and any follow-up recommendations from WPAC. Recommendations include documentation of activities, and the needs and challenges toward making progress in protecting Iowa’s water resources, identified by WPAC in coordination with all agencies and stakeholders in the management of the state’s water resources in a sustainable, fiscally responsible, and environmentally conscientious manner.

Watershed Planning Advisory Council Annual Report January 31, 2012

This report provides updates on the WPAC recommendations to legislature, including actions taken on those recommendations and any follow-up recommendations from WPAC. Recommendations include documentation of activities, and the needs and challenges toward making progress in protecting Iowa’s water resources, identified by WPAC in coordination with all agencies and stakeholders in the management of the state’s water resources in a sustainable, fiscally responsible, and environmentally conscientious manner.