Embriologia e desenvolvimento pós-seminal de espécies de Poaceae (Poales)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação de um teste bioquímico de triagem para a detecção de indivíduos heterozigotos para a fenilcetonúria

A fenilcetonúria (PKU) é uma doença metabólica hereditária resultante da deficiência da enzima fenilalanina hidroxilase (PAH) que converte o aminoácido fenilalanina em tirosina. O presente estudo teve como objetivo investigar o metabolismo dos aminoácidosfenilalanina (Phe) e tirosina (Tyr) em heterozigotos para PKU, nas condições de jejum e após uma sobrecarga oral de Phe (25 mg/Kg), aplicando diferentes parâmetros bioquímicos (níveis de Phe e Tyr e as relações Phe/Tyr e Phe²/Tyr), a fim de identificar a melhor variável que discrimine heterozigotos para a PKU de indivíduos normais. O protocolo empregado foi a dosagem de Phe e Tyr plasmática nas situações de jejum, 30, 45, 60 e 90 minutos após a sobrecarga de Phe na dose de 25mg/kg. A amostra foi composta de 50 indivíduos: 23 heterozigotos obrigatórios (10 homens e 13 mulheres) e um grupo controle de 27 indivíduos hígidos (13 homens e 14 mulheres), obedecendo a critérios de pareamento: gênero e faixa etária (18 a 44 anos). Para analisar o efeito da sobrecarga oral de Phe em cada grupo, os resultados dos parâmetros Phe, Tyr, Phe/Tyr e Phe2/Tyr após a sobrecarga foram comparadoscom os observados na situação de jejum. Foram realizadas inferências estatísticas entre os grupos nos aspectos longitudinal e transversal e aplicados os testes t de Student , teste de Wilcoxon , teste t de Student e o seu equivalente não paramétrico e teste U de Mann-Whitney. Na avaliação da Curva ROC das variáveis utilizadas, os três melhores parâmetros para classificar indivíduos heterozigotos de normais foram: a dosagem da Phe a 45 e 90 minutos, assim como o resultado da fração micromolar Phe2/Tyr após 90 minutos da sobrecarga. A função discriminante revelou 86% de acurácia e uma classificação correta de 94,4% dos indivíduos heterozigotos para PKU.

Imagem do pensamento: do antropológico ao acontecimento na Educação

Pós-graduação em Educação - FFC

Herpetofauna of Paranapiacaba: expanding our knowledge on a historical region in the Atlantic forest of southeastern Brazil

The largest area of preserved Atlantic forest is located in the southern portion of Brazil. The region of Paranapiacaba is depicted in Brazilian zoological studies as one of the first and most intensely sampled areas of the state of São Paulo.We provide a concise list of reptiles and amphibians from the Paranapiacaba Municipal Park. It represents the first comprehensive survey of the group in the area. We recorded 136 species of reptiles and amphibians from field surveys, museum collections and the literature. The anuran diversity of Paranapiacaba is greater than that of Estação Ecológica de Boracéia, which has been considered the most distinctive areas in São Paulo in terms of amphibian diversity. The rich history of herpetological research in the region, including the occurrence of the two most threatened species in Brazil, converts the area to an important conservation landmark for the Brazilian herpetofauna.

Inteligência competitiva organizacional: um modelo apoiado nos comportamentos de busca, compartilhamento e uso de informação e de TIC

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Measurement of Radiant Energy using Pyroelectric Polymer/Ceramic Composite

Monitoring non-ionizing radiant energy is increasingly demanded for many applications such as automobile, biomedical and security system. Thermal type infrared (IR) sensors can operate at room temperature and pyroelectric materials have high sensitivity and accuracy for that application. Working as thermal transducer pyroelectric sensor converts the non-quantified thermal flux into the output measurable quantity of electrical charge, voltage or current. In the present study the composite made of poly(vinylidene fluoride) -PVDF and lead zirconate titanate (PZT) partially recovered with polyaniline (PAni) conductor polymer has been used as sensor element. The pyroelectric coefficient p(T) was obtained by measuring the pyroelectric reversible current, i.e., measuring the thermally stimulated depolarization current (TSDC) after removing all irreversible contribution to the current such as injected charge during polarization of the sample. To analyze the sensing property of the pyroelectric material, the sensor is irradiated by a high power light source (halogen lamp of 250 W) that is chopped providing a modulated radiation. A device assembled in the laboratory is used to change the light intensity sensor, an aluminum strip having openings with diameters ranging from 1 to 10 mm incremented by one millimeter. The sensor element is assembled between two electrodes while its frontal surface is painted black ink to maximize the light absorption. The signal from the sensor is measured by a Lock-In amplifier model SR530 -Stanford Research Systems. The behavior of the output voltage for an input power at several frequencies for PZT-PAni/PVDF (30/ 70 vol%) composite follows the inverse power law (1/ f) and the linearity can be observed in the frequency range used.

Entanglement universality of two-qubit X-states

We demonstrate that for every two-qubit state there is a X-counterpart, i.e., a corresponding two-qubit X-state of same spectrum and entanglement, as measured by concurrence, negativity or relative entropy of entanglement. By parametrizing the set of two-qubit X-states and a family of unitary transformations that preserve the sparse structure of a two-qubit X-state density matrix, we obtain the parametric form of a unitary transformation that converts arbitrary two-qubit states into their X-counterparts. Moreover, we provide a semi-analytic prescription on how to set the parameters of this unitary transformation in order to preserve concurrence or negativity. We also explicitly construct a set of X-state density matrices, parametrized by their purity and concurrence, whose elements are in one-to-one correspondence with the points of the concurrence versus purity (CP) diagram for generic two-qubit states. (C) 2014 Elsevier Inc. All rights reserved.

ENDO-OLIGOPEPTIDASE-A, A PUTATIVE ENKEPHALIN-GENERATING ENZYME, IN THE VERTEBRATE RETINA

Endo-oligopeptidase A, EC 3.4.22.19, converts small enkephalin-containing peptides into the corresponding enkephalins in vitro. We investigated the presence of endooligopeptidase A in the retina and its possible colocalization with enkephalins in retinal neurons. The specific activity of endo-oligopeptidase A found in pigeon retinae (30.3 +/- 7.3 mU/mg, mean +/- standard deviation) was four times higher than in rabbit retinae (7.0 +/- 1.1 mU/mg). The enzyme activity was not modified by EDTA, but it was enhanced by dithiothreitol and inhibited by zinc and 5,5'-dithiobis(2-nitrobenzoic acid). Immunohistochemical experiments with a purified antiserum against rabbit endo-oligopeptidase A revealed labeled neurons in both the inner nuclear layer and the ganglion cell layer of pigeon and rabbit retinae. Double-labeling immunofluorescence experiments demonstrated that about 90% of neurons containing endo-oligopeptidase A-like immunoreactivity also contained [Leu5]-enkephalin-like immunoreactivity. These colocalization results may represent an important step toward the demonstration of the possible involvement of endo-oligopeptidase A in enkephalin generation in vivo.

Determinação dos esforços em lajes pelo métodos dos elementos de contorno

Through deductions and formulations of the equations governing the behavior of plates elastic and thin based Kirchhoff theory, it is evident that it is justifiable to the complication of the numerical methods considering the complexity of the equations that describe the physical behavior of these elements and obtaining analytical solutions for specific situations. This study is directed to the application of the numerical method which is based on discretizations to the simplest elements which results in the reduction of data to be processed from. The numerical method in question is the Boundary Element Methods (BEM), as the name suggests, the discretizations are only the edges of the elements. The BEM converts the complex integral equations, in sums of functions that reduce the unknowns at the nodes that define the ends of discrete elements, obtaining internal values to elements using interpolation functions. Confirming the need and usefulness of the BEM, apply, then the foundations necessary to the specific cases of Civil Engineering where traditional methods do not provide the desired support, leaving in question the security situations and economics of the projects

Classificação e quantificação de tecidos Biológicos para construção de fantomas pediátricos

Paediatric diagnostic radiology can be considered as a separate specialty and with distinct characteristics of the radiology applied in adult patients. This in reason of the variability in the anatomical structures size and bigger sensitivity of tissues. The literature present in its majority methodologies for segmentation and tissue classification in adult patients, and works on tissue quantification are rare. This work had for objective the development of a biological tissue classifier and quantifier algorithm, from histograms, and that converts the quantified average thickness of these tissues for its respective simulator materials. The results will be used in the optimization process of paediatrics images, in future works, since these patients are frequently over exposed to the radiation in the repeated attempts of if getting considered good quality radiographic images. The developed algorithm was capable to read and store the name of all the archives, in the operational system, to filter artifacs, to count and quantify each biological tissues from the histogram of the examination, to obtain the biological tissues average thicknesses and to convert this value into its respective simulator material. The results show that it is possible to distinguish bone, soft, fat and pulmonary tissues from histograms of tomographic examinations of thorax. The quantification of the constituent materials of anthropomorphic phantom made by the algorithm, compared with the data of literature shows that the biggest difference was of 21,6% for bone. However, the literature shows that variations of up to 30% in bone thickness do not influence of significant form in the radiographic image quality. The average thicknesses of biological tissues, quantified for paediatrics patients, show that one phantom can simulate patients with distinct DAP ranges, since variations... (Complete abstract click electronic access below)

Maximally genuine multipartite entangled mixed X-states of N-qubits

For every possible spectrum of 2(N)-dimensional density operators, we construct an N-qubit X-state of the same spectrum and maximal genuine multipartite (GM-) concurrence, hence characterizing a global unitary transformation that -constrained to output X-states-maximizes the GM-concurrence of an arbitrary input mixed state of N qubits. We also apply semidefinite programming methods to obtain N-qubit X-states with maximal GM-concurrence for a given purity and to provide an alternative proof of optimality of a recently proposed set of density matrices for the purpose, the so-called X-MEMS. Furthermore, we introduce a numerical strategy to tailor a quantum operation that converts between any two given density matrices using a relatively small number of Kraus operators. We apply our strategy to design short operator-sum representations for the transformation between any given N-qubit mixed state and a corresponding X-MEMS of the same purity.

Learning HMMs for nucleotide sequences from amino acid alignments

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Conversões e negociações: um estudo dos relatos de missionários protestantes da Church Missionary Society em Uganda-África (1876-1890)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Expert system to detect incipient fauts in rotating machines using fuzzy logic and virtual instrumentation

This paper refers to the design of an expert system that captures a waveform through the use of an accelerometer, processes the signal and converts it to the frequency domain using a Fast Fourier Transformer to then, using artificial intelligence techniques, specifically Fuzzy Reasoning, it determines if there is any failure present in the underlying mode of the equipment, such as imbalance, misalignment or bearing defects.

Sophie Calle: entre imagens e palavras

A relação de Sophie Calle com dois textos ficcionais, de autoria de Hervé Guibert e Paul Auster, permite discutir um ponto central de sua poética: a atuação como performer, colocada por alguns críticos sob o signo do situacionismo. Como suas performances envolvem uma narrativa, foram analisados seus aspectos fotográficos e verbais, tendo como epicentro Suíte veneziana (1980). Qual o papel da fotografia nas narrativas de Calle, nas quais ela é personagem de si mesma? A fotografia é vestígio de acontecimentos reais e seu aspecto documental corrobora a neutralidade dos relatos escritos. É, ao mesmo tempo, fruto de um gesto performático, o qual, ao designar determinados fatos, converte a realidade em imagem.