999 resultados para Calendario-Francia-S. XVIII


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Arkit: 1 arkintunnukseton lehti, A4 B1.

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En el número V de "Contribuciones a la Ictiologia" se dán normas para el estudio sistemático de los organos ciatiformes, que proporcionaron a los Gobiidae de Europa un medio seguro de ordenación genérica y distinción específica. Se añade el estudio de la colección del Laboratorio Aragó, de Banyuls-sur-mer, Francia. En el número VI de "Contribuciones a la Ictiología" se aloja el Gobiosoma parri Ginsburg en el nuevo gênero Austrogobius De Buen, y se dán las características que lo distinguen, especialmente la distribución de tubos mucosos y geniporos.

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Julkaisussa: Geographia universalis, vetus et nova, complectens Claudii Ptolemaei Alexandrini enarrationis libros VIII

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Julkaisussa: Terzo volume delle navigationi et viaggi raccolto gia da M. Gio. Battista Ramusio nel quale si contengono

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Julkaisussa: Geographiae Claudii Ptolemaei Alexandrini, philosophi ac mathematici praestantissimi, libri VIII

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Julkaisussa: Geographia universalis, vetus et nova, complectens Claudii Ptolemaei Alexandrini enarrationis libros VIII

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Acute renal failure (ARF) is a frequent complication of Gram-negative sepsis, with a high risk of mortality. Lipopolysaccharide (LPS)-induced ARF is associated with hemodynamic changes that are strongly influenced by the overproduction of nitric oxide (NO) through the cytokine-mediated up-regulation of inducible NO synthase. LPS-induced reductions in systemic vascular resistance paradoxically culminate in renal vasoconstriction. Collagen XVIII is an important component of the extracellular matrix expressed in basement membranes. Its degradation by matrix metalloproteases, cathepsins and elastases results in the formation of endostatin, claimed to have antiangiogenic activity and to be a prominent vasorelaxing agent. We evaluated the expression of endostatin/collagen XVIII in an endotoxemic ARF model. ARF was induced in C57BL/6 mice by intraperitoneal injection of LPS (10 mg/kg) followed by sacrifice 4 and 12 h later. Kidney tissue was the source of RNA and protein and the subject of histological analysis. As early as 4 h after LPS administration, blood urea, creatinine and NO levels were significantly increased compared to control. Endostatin/collagen XVIII mRNA levels were 0.71 times lower than sham-inoculated mice 4 h after LPS inoculation, returning to normal levels 12 h after LPS inoculation. Immunohistological examination revealed that acute injury caused by LPS leads to an increase of endostatin basement membrane staining in association with the decrease of CD31 endothelial basement membrane staining. These results indicate that in the early phase of endotoxemic ARF the endostatin levels were not regulated by gene expression, but by the metabolism of collagen XVIII.

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Teoksessa: Geographiae Claudii Ptolemaii Alexandrini.