Majmūʻah : manuscript, 1848-1857

1. Kitāb Maqṣad al-asná fī dhikr mā yataʻallaq bi-al-asmāʼ al-ḥusná / Aḥmad Zarrūq, 1267 AH [1850 or 51 AD] (ff. 1r-21v) -- 2. Sharḥ sayyid al-istighfār / ʻAlī Mahāyimī, 1265 AH [1848 or 49 AD] (ff. 25r-32v) -- 3. Hādhā al-suʼāl nuqila min asʼilah suʼila ʻanhā ... Muḥammad ibn Sulaymān al-Kurdī al-Shāmī al-Madanī (ff. 33r-39r) -- 4. Hādhā fawāyid nafīsah ... wa-mimmā suʼila ʻanhu ... al-Shaykh Saʻīd Sunbul al-Makkī, 1273 AH [1856 or 57 AD] (ff. 39r-51r) -- 5. Mā qawl al-sādah al-Ḥanafīyah fī ʻaṣīr qaṣab al-sukkar / ʻAbd al-Wahhāb al-Suyūṭī al-Ḥanafī, ʻAbd al-Qādir al-Rāfiʻī al-Ḥanafī, ʻAbd al-Raḥmān al-Baḥrāwī al-Ḥanafī, Muḥammad al-Rāfiʻī al-Ḥanafī (ff. 51v-55r).

Hādhā kitāb Sharḥ khawāṣṣ al-manẓūmah al-musammāh bi-al-Dimyāṭīyah

Lithographed.

Rafʻ al-iltibās ʻan munkar al-iqtibās / taʼlīf Shaykh mashāyikh al-Islām Imām al-aʼimmah al-aʻlām ... Shaykh al-Islām al-Shams Muḥammad ibn Abī al-Luṭf : manuscript, 1585

Copy completed at the end of Rabīʻ al-Ākhir 993 [April 1585], apparently from author's copy.

Risālah fī taqrīr al-adillah wa-al-shawāhid ʻalá wujūb al-ḥufwah fī al-masājid / taʼlīf Sayyidinā wa-Mawlānā Shaykh mashāyikh al-Islām ... al-Shaykh Muḥammad ibn Abī al-Luṭf : manuscript, 1584

Foliated 184-188; paginated 1-9, both in Arabic numerals.

Kitāb al-Kashf ʻan mujāwazat hādhihi al-ummah al-alf / taʾlīf al-Imām aʻĀlim al-ʻAllāmah al-Ḥāfiẓ al-Mujtahid Abī Bakr ibn ʻAbd al-Raḥmān Jalāl al-Dunyā wa-al-Dīn al-Suyūṭī al-Shāfiʻī : manuscript, 1584

Dated 992 [1584].

Hādhihi risālah tusammá Awāʼil al-awāʼil / taʼlīf al-Imām al-ʻAllāmah ʻAbd al-Karīm Afandī al-Qāḍī al-Araklī : manuscript, undated

Foliated 203-227; paginated 1-49, both in Arabic numerals.

Majmūʻ tawārīkh lā baʼsa bihi : mansucript, undated

Anonymous chronograms from the years 1187-1200 [1773-1786].

Kitāb Dhikr al-ikhtilājāt fī badan al-insān : manuscript, undated

Paginated 1-7 in Arabic numerals.

Hādhihi qaṣīdah jāmiʻah li-ghālib aḥwāl yawm al-qiyāmah wa-ismuhā Qilādat al-durr al-manthūr fī dhikr al-baʻth wa-al-nushūr : manuscript, undated

Paginated 1-5 in pencil in Arabic numerals.

Hādhā kitāb al-Talkhīṣ min mīzān al-kalimāt al-jafrīyah wa-ḥawādith al-sinīn al-hijrīyah : manuscript, undated

With: Thalāthat alwāḥ al-jafrīyah al-mutaḍamminah asmāʼ mulūk Āl ʻUthmān (f. 4v-5r) -- al-Durr al-munaẓẓam fī sharḥ al-ism al-aʻẓam / ʻAbd al-Raḥmān ibn Muḥammad al-Bisṭāmī (f. 5v-39r).

Kitāb al-Taʻarruf li-madhhab ahl al-taṣawwuf : manuscript, 1605

Title from f. 2v.

Mecmua : manuscript, undated

1. Turkish letter samples (ff. 1v-10v) -- 2. Risālah fī bayān ḥurmat shurb dukhān al-tunbāk / Mawlānā ʻAbd al-Nāfiʻ (ff. 11v-19v) -- 3. Risālah fī lubs al-aḥmar al-baḥt / Shaykh Qāsim (ff. 20v-21v) -- 4. Excerpt from Ibn al-ʻArabī (ff. 23v-24r) -- 5. Excerpt from Ayyuhā al-walad of al-Ghazzālī (ff. 26v-28r) -- 6. Excerpt from Kitāb Laṭāʼif al-adabīyah (ff. 30r-32r) -- 7. Şerh-i Hilyeti'n-Nebî (ff. 33r-35v) -- 8. Sharḥ Jannat al-asmāʼ wa-al-āyāt Allāh [sic] (ff. 35v-38v) -- 9. Fetvâlar (ff. 39v-96v) -- 10. ??? (ff. 98r-103v) -- 11. Persian and Turkish poems (ff. 104r-133r) -- 12. Manzume-i Nidâî Kaysûnîzâde (ff. 134v-157v) -- 13. Excerpts, hadiths and fatwas (ff. 158r-162r) -- Mā jāʼa fī ṭarīq al-taṣawwuf wa-arkānihi (ff. 162v-164v).

al- Durr al-munaẓẓam fī sharḥ al-ism al-aʻẓam : manuscript, undated

Written in one column, 20 lines per page, in black rubricated in red. Text framed within double red lines and each line framed within a red line.

Dībājah-ʼi Tafsīr / li-Mawlānā Shaykh Mashāyikh al-Islām Muftī al-zamān farīd al-ʻaṣr wa-al-awān Abū al-Suʻūd Muḥammad al-ʻImādī : manuscript, undated

Foliated 198-202; paginated 1-9, both in Arabic numerals.

Murine Model for Preclinical Studies of Var2CSA-Mediated Pathology Associated with Malaria in Pregnancy

Plasmodium falciparum infection during pregnancy leads to abortions, stillbirth, low birth weight, and maternal mortality. Infected erythrocytes (IEs) accumulate in the placenta by adhering to chondroitin sulfate A (CSA) via var2CSA protein exposed on the P. falciparum IE membrane. Plasmodium berghei IE infection in pregnant BALB/c mice is a model for severe placental malaria (PM). Here, we describe a transgenic P. berghei parasite expressing the full-length var2CSA extracellular region (domains DBL1X to DBL6ε) fused to a P. berghei exported protein (EMAP1) and characterize a var2CSA-based mouse model of PM. BALB/c mice were infected at midgestation with different doses of P. berghei-var2CSA (P. berghei-VAR) or P. berghei wild-type IEs. Infection with 10(4) P. berghei-VAR IEs induced a higher incidence of stillbirth and lower fetal weight than P. berghei At doses of 10(5) and 10(6) IEs, P. berghei-VAR-infected mice showed increased maternal mortality during pregnancy and fetal loss, respectively. Parasite loads in infected placentas were similar between parasite lines despite differences in maternal outcomes. Fetal weight loss normalized for parasitemia was higher in P. berghei-VAR-infected mice than in P. berghei-infected mice. In vitro assays showed that higher numbers of P. berghei-VAR IEs than P. berghei IEs adhered to placental tissue. Immunization of mice with P. berghei-VAR elicited IgG antibodies reactive to DBL1-6 recombinant protein, indicating that the topology of immunogenic epitopes is maintained between DBL1-6-EMAP1 on P. berghei-VAR and recombinant DBL1-6 (recDBL1-6). Our data suggested that impairments in pregnancy caused by P. berghei-VAR infection were attributable to var2CSA expression. This model provides a tool for preclinical evaluation of protection against PM induced by approaches that target var2CSA.