993 resultados para 312
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Streaming applications demand hard bandwidth and throughput guarantees in a multiprocessor environment amidst resource competing processes. We present a Label Switching based Network-on-Chip (LS-NoC) motivated by throughput guarantees offered by bandwidth reservation. Label switching is a packet relaying technique in which individual packets carry route information in the form of labels. A centralized LS-NoC Management framework engineers traffic into Quality of Service (QoS) guaranteed routes. LS-NoC caters to the requirements of streaming applications where communication channels are fixed over the lifetime of the application. The proposed NoC framework inherently supports heterogeneous and ad hoc system-on-chips. The LS-NoC can be used in conjunction with conventional best effort NoC as a QoS guaranteed communication network or as a replacement to the conventional NoC. A multicast, broadcast capable label switched router for the LS-NoC has been designed. A 5 port, 256 bit data bus, 4 bit label router occupies 0.431 mm(2) in 130 nm and delivers peak bandwidth of 80 Gbits/s per link at 312.5 MHz. Bandwidth and latency guarantees of LS-NoC have been demonstrated on traffic from example streaming applications and on constant and variable bit rate traffic patterns. LS-NoC was found to have a competitive AreaxPower/Throughput figure of merit with state-of-the-art NoCs providing QoS. Circuit switching with link sharing abilities and support for asynchronous operation make LS-NoC a desirable choice for QoS servicing in chip multiprocessors. (C) 2013 Elsevier B.V. All rights reserved.
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ZnO:Eu (0.1 mol%) nanopowders have been synthesized by auto ignition based low temperature solution combustion method. Powder X-ray diffraction (PXRD) patterns confirm the nanosized particles which exhibit hexagonal wurtzite structure. The crystallite size estimated from Scherrer's formula was found to be in the range 35-39 nm. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) studies reveal particles are agglomerated with quasi-hexagonal morphology. A blue shift of absorption edge with increase in band gap is observed for Eu doped ZnO samples. Upon 254 nm excitation, ZnO:Eu nanopowders show peaks in regions blue (420-484 nm), green (528 nm) and red (600 nm) which corresponds to both Eu2+ and Eu3+ ions. The electron paramagnetic resonance (EPR) spectrum exhibits a broad resonance signal at g= 4.195 which is attributed to Eu2+ ions. Further, EPR and thermo-luminescence (TL) studies reveal presence of native defects in this phosphor. Using TL glow peaks the trap parameters have been evaluated and discussed. (C) 2014 Elsevier B.V. All rights reserved.
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Activation of apoptosis signal regulating kinase 1 (ASK1)-p38 MAPK death signaling cascade is irn plicated in the death of dopaminergic neurons in substantia nigra in Parkinson's disease (PD). We investigated upstream activators of ASK1 using an MPTP mouse model of parkinsonism and assessed the temporal cascade of death signaling in ventral midbrain (VMB) and striatum (ST). MPTP selectively activated ASK1 and downstream 1)38 MAPK in a time dependent manner in VMB alone. This occurred through selective protein thiol oxidation of the redox-sensitive thiol disulfide oxidoreductase, thiorcdoxin (Trxl), resulting in release of its inhibitory association with ASK1, while glutathione-S-transferase ji 1 (GSTM1) remained in reduced form in association with ASK1. Levels of tumor necrosis factor (TNF), a known activator of ASK1, increased early after MPTP in VMB. Protein ovariation netvvork analysis (PCNA) using protein states as nodes revealed TNF to be an important node regulating the ASK1 signaling cascade. In confirmation, blocking MPTP-mecliated TNF signaling through intrathecal administration of TNFneutralizing antibody prevented Trxl oxidation and downstream ASK1-p38 MAPK activation. Averting an early increase in TNF, which leads to protein thiol oxidation resulting in activation of ASK1-p38 signaling, may be critical for neuroprotection in PD. Importantly, network analysis can help in understanding the cause/effect relationship within protein networks in complex disease states. (C) 2015 Published by Elsevier Inc.
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Lanthanide complexes Ln(DTPAAQ)(DMF)] (1-3) (Ln - Pr (1), Eu (2), Tb (3), H(3)DTPAAQ - N, N `'-bis(3-amidoquinolyl) diethylenetriamine-N, N', N `'-triacetic acid, DMF - N, N-dimethylformamide) were studied for their structures, photophysical properties, DNA and protein binding, DNA photocleavage, photocytotoxicity and cellular internalization. The crystal structures of complexes Ln(DTPAAQ)(DMF)] (1-3) display a discrete mononuclear nine-coordinate {LnN(3)O(6)} tricapped-trigonal prism (TTP) coordination geometry. The europium and terbium complexes show strong luminescence properties in the visible region having a long luminescence lifetime (tau = 0.51-0.64 ms). The conjugated 3-aminoquinoline moieties act as efficient light harvesting antennae, which upon photoexcitation transfer their energy to Eu(III) or Tb(III) for their characteristic D-5(0) -> F-7(J) or D-5(4) -> F-7(J) f-f transitions respectively. The complexes display efficient binding affinity to DNA (K-b = 3.4 x 10(4) - 9.8 x 10(4) M-1) and BSA (KBSA = 3.03 x 10(4) - 6.57 x 10(4) M-1). Europium and terbium complexes give enhanced luminescence upon interacting with CT-DNA suggesting possible luminescence-based sensing applications for these complexes. Complexes 1-3 show moderate cleavage of supercoiled (SC) DNA to its nicked circular (NC) form on exposure to UV-A light of 312 nm involving formation of singlet oxygen (O-1(2)) and hydroxyl radicals (cOH) in type-II and photoredox pathways. Eu(III) and Tb(III) complexes exhibit remarkable photocytotoxicity with human cervical cancer cell line (HeLa) (IC50 = 20.7-28.5 mM) while remaining essentially noncytotoxic up to 150 mM in the dark. Complexes are nontoxic in nature thus suitable for designing cellular imaging agents. Fluorescence microscopy data reveal primarily cytosolic localization of the Eu(III) and Tb(III) complexes in HeLa cells.
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En la época de postrera 2005, se realizó la evaluación de 9 genotipos de arroz procedentes de Colombia y una variedad comercial de Nicaragua (INTA DORADO). El experimento se realizó en la localidad de Paso Real, de San Isidro, Matagalpa, ubicado a los 12º54 ́ latitud norte y 86º11 ́ longitud oeste, a una altura de 457 msnm. La finalidad del ensayo fue identificar líneas con buen rendim iento de grano, calidad molinera, tolerancia a enfermedades y buena adaptabilidad a las condiciones de riego. El diseño experimental fue el de bloque completo al azar (BCA) con 10 tratamientos y 4 repeti ciones. Utilizándose ANDEVA y separación de media SNK ( ∞ =0.05). En la mayoría de las variables evaluadas se determino que existe efecto significativo y altamente significativo entre los diferent es tratamientos. Los principales resultados evidencian que los genotipos L-9, L-39, POB L1-34, POBL 3- 13, alcanzaron los mayores rendimie ntos con producciones de 5,312, 5,193, 5,082.50, 5,044 kg ha -1 respectivamente superando al testigo INTA DORADO que obtuvo el menor rendimiento con 3,506 kg ha -1 . Los componentes del rendimiento: núme ro de granos por panículas, porcentaje de fertilidad de las panículas, peso de 1000 granos y macollamiento por planta definieron la mayor productividad de los genotipos de mayor rendimiento (L-9, L-39, POBL1-34, POBL 3-13), siendo estos los genotipos que presentaron mayor resistencia a enfermedades. Además estos genotipo s presentan; buen porte de planta (tipo semienano), tolerancia al acame y ciclo intermedio. El testigo INTA DORADO y las líneas L-9, POBL 1-34 presentaron una calidad industrial de 94/06, 92/08 y 92/08, con respecto a la relación de grano entero/quebrado.
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Tbe present study was carried out in the strip of land coast between Pearls Lagoon community and the Caribbean sea, in the nearness of Pinar lagoon, 25 km to the north of Bluefields. The geographical coordinates of the area are 12" 13' N and 83" 42' west. Tbe climate presents an annua! rninfall of 4 250 mm, an avera· ge temperature of 26 "C and a relative humidity of 89 %. The topography is plain and tbe elevation oscillates between O· 10 masl. The ma.in objective of the study was to evaluate the forest conditions in which forest of P. Caribaea var .. Jwndurei'ISis ealled the Pinal are found. The methodology employed consisted of gathering all information using air pllotographs and topograpbieal maps to defined the area and stands group (designed A, B, C, D, E, F and G). Two block and seven stands were found, in which invent.ory lines with sample plots of 500 m1 each one were employed to measure the indivíduals with DBH over 10 cm. The intensily it shows ís of !5% and was measured diameter, height, age and other. In tbis forest there where found seven stands with a total area covered with pine of 312.42 has. The average age is 23 years and estirnated total volume of 97.4 ms of wood. The density is of 60,61 trees hectare, with an average volume of 13.02 m3 /has and a commercial volume of 8.29 m' 1 has. Where found lndices of place 12 (stands G), 9 y 6. Besides, the 6.3.64 % of the trees has a satisfactory tendency of growlh (quality l and 2). lt can be concluded that the resource is in badly state due to intensive exploitations and annual f!fCS; is a young forest (23 years old), dotninated by índi viduals of small diameters (10-25 cm) and medium height (5-25 m); the available areas or with possibilities of being planting are: estimated in 468.64 has. This forest has a half annual increment of 1.4.3 cm/year, which is considered excellent and is c1assified with Clas P-III, FAO Classification by forests stratification.
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在由光学多道分析仪收集的氢氧气体爆轰激励下铝粉快速反应光谱中,观察到AlOB2Σ+→X2Σ+跃迁Δv=0带系的光谱特征与通常铝氧化反应的光谱特征不同。经分析是因为存在一个从467nm开始向长波方增强的连续辐射,它改变了该波长区AlO分子的辐射特征。这一连续辐射可能是由铝与水蒸汽发生水合反应生成,而处于不同激发态的多原子分子HAlOH产生
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在已论证过的应变软化效应对形成剪切带状分叉的作用的基础上,本文研究了:(1)什么受力情况最易激发剪切带(2)采用什么力学模型和参数可以模拟材料中的曲线型带状分叉。
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<正> 会议于1984年11月2—7日在杭州举行,由中国宇航学会、中国航空学会和中国力学学会共同主办,全国科研、设计、生产部门和大专院校13个学院87个单位的221名代表参加了会议,大会收到学术报告312篇,接受了182篇,会前即预印了论文集,120篇论文分别在材料工艺、性能测试与应用、静动态力学性能、结构设计分析以及金属基复合材料五个组
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In order to capture shock waves and contact discontinuities in the field and easy to program with parallel computation a new algorithm is developed to solve the N-S equations for simulation of R-M instability problems. The method with group velocity control is used to suppress numerical oscillations, and an adaptive non-uniform mesh is used to get fine resolution. Numerical results for cylindrical shock-cylindrical interface interaction with a shock Mach number Ms=1.2 and Atwood number A=0.818, 0.961, 0.980 (the interior density of the interface/outer density p(1)/p(2) = 10, 50, 100, respectively), and for the planar shock-spherical interface interaction with Ms=1.2 and p(1)/p(2) = 14.28are presented. The effect of Atwood number and multi-mode initial perturbation on the R-M instability are studied. Multi-collisions of the reflected shock with the interface is a main reason of nonlinear development of the interface instability and formation of the spike-bubble structures In simulation with double mode perturbation vortex merging and second instability are found. After second instability the small vortex structures near the interface produced. It is important factor for turbulent mixing.
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Documento com duas páginas-de-rosto, em português e francês. Título em francês : Rapport présenté a Son Ex. M. le Ministre de l'Industrie, de la Voirie et des Travaux Publics