College Book 6, 1726-1790

College Book 6 is often referred to as the Hollis book, reflecting its contents. It was created following an April 4, 1726 Corporation vote that "Mr. Treasurer procure a Book, into which shall be transmitted, and a Register kept of, Mr Hollis's Rules, orders, Gifts & Bounties past & to come; together with ye Names & age, & Charecter of his Scholars, ye time of their Entry and Dismission; and also all ye Votes of ye Overseers & Corporation from time to time relating to ye said orders, Bounties & Scholars of the said Mr Hollis." Entries are primarily in Benjamin Wadsworth's hand and record donations from Thomas Hollis and his descendants, with transcriptions of related Corporation minutes. They also provide detailed information about the allocation of Hollis funds and scholarships, and the rules governing the Hollis Professorship of Divinity (established in 1721) and the Hollis Professorship of Mathematics and Natural Philosophy (established in 1727). The volume also contains inventories of books in the official library of the Hollis Professor of Divinity and two inventories – created in 1779 and in 1790 – of the mathematical and philosophical apparatus purchased with Hollis funds. Many entries related to the purchase of scientific instruments and supplies include the cost in sterling of each item. Also included are entries related to financial accounts and expenditures, as well as copies of letters from Nathaniel Hollis.

Human naïve regulatory T-cells feature high steady-state turnover and are maintained by IL-7

Naïve FoxP3-expressing regulatory T-cells (Tregs) are essential to control immune responses via continuous replenishment of the activated-Treg pool with thymus-committed suppressor cells. The mechanisms underlying naïve-Treg maintenance throughout life in face of the age-associated thymic involution remain unclear. We found that in adults thymectomized early in infancy the naïve-Treg pool is remarkably well preserved, in contrast to conventional naïve CD4 T-cells. Naïve-Tregs featured high levels of cycling and pro-survival markers, even in healthy individuals, and contrasted with other circulating naïve/memory CD4 T-cell subsets in terms of their strong γc-cytokine-dependent signaling, particularly in response to IL-7. Accordingly, ex-vivo stimulation of naïve-Tregs with IL-7 induced robust cytokine-dependent signaling, Bcl-2 expression, and phosphatidylinositol 3-kinase (PI3K)-dependent proliferation, whilst preserving naïve phenotype and suppressive capacity. Altogether, our data strongly implicate IL-7 in the thymus-independent long-term survival of functional naïve-Tregs, and highlight the potential of targeting the IL-7 pathway to modulate Tregs in different clinical settings.

Differences in larval nutritional requirements and female oviposition preference reflect the order of fruit colonization of Zaprionus indianus and Drosophila simulans

Species coexist using the same nutritional resource by partitioning it either in space or time, but few studies explore how species-specific nutritional requirements allow partitioning. Zaprionus indianus and Drosophila simulans co-exist in figs by invading the fruit at different stages; Z. indianus colonizes ripe figs, whereas D. simulans oviposits in decaying fruit. Larvae feed on yeast growing on the fruit, which serves as their primary protein source. Because yeast populations increase as fruit decays, we find that ripe fruit has lower protein content than rotting fruit. Therefore, we hypothesized that Z. indianus and D. simulans larvae differ in their dietary requirements for protein. We used nutritional geometry to assess the effects of protein and carbohydrate concentration in the larval diet on life history characters in both species. Survival, development time, and ovariole number respond differently to the composition of the larval diet, with Z. indianus generally performing better across a wider range of protein concentrations. Correspondingly, we found that Z. indianus females preferred to lay eggs on low protein foods, while D. simulans females chose higher protein foods for oviposition when competing with Z. indianus. We propose the different nutritional requirements and oviposition preference of these two species allows them to temporally partition their habitat.

¿Qué significa tener una beca de estudio de la Comisión de Investigaciones Científicas de la Provincia de Buenos Aires? Relato de una experiencia

Las becas que otorga la Comisión de Investigaciones Científicas de la Provincia de Buenos Aires (CIC) cada año se presentan como una opción interesante para alumnos avanzados y graduados que deseen iniciarse en la investigación científica y técnica. Tradicionalmente, el área de desempeño laboral y profesional de los graduados de las carreras de Licenciatura y Profesorado en Educación Física ha sido la docencia, por ello, este documento tiene por objetivo explicar, a partir de una experiencia personal, qué se requiere para acceder a una Beca de Estudio de la Comisión de Investigaciones Científicas de la Provincia de Buenos Aires y cuáles son los antecedentes más importantes para la aprobación de este tipo de beca. Se expondrá el plan de investigación de la autora, el cual fue aprobado y continúa en actividad al momento, y por último, se describirán las tareas que el becario debe desempeñar una vez obtenida la Beca de Estudio

¿Qué significa tener una beca de estudio de la Comisión de Investigaciones Científicas de la Provincia de Buenos Aires? Relato de una experiencia

Las becas que otorga la Comisión de Investigaciones Científicas de la Provincia de Buenos Aires (CIC) cada año se presentan como una opción interesante para alumnos avanzados y graduados que deseen iniciarse en la investigación científica y técnica. Tradicionalmente, el área de desempeño laboral y profesional de los graduados de las carreras de Licenciatura y Profesorado en Educación Física ha sido la docencia, por ello, este documento tiene por objetivo explicar, a partir de una experiencia personal, qué se requiere para acceder a una Beca de Estudio de la Comisión de Investigaciones Científicas de la Provincia de Buenos Aires y cuáles son los antecedentes más importantes para la aprobación de este tipo de beca. Se expondrá el plan de investigación de la autora, el cual fue aprobado y continúa en actividad al momento, y por último, se describirán las tareas que el becario debe desempeñar una vez obtenida la Beca de Estudio

County scholarship regulations /

"March, 1951."

Fellows of the Social Science Research Council, 1925-1951.

Mode of access: Internet.

Journal of the Iron and Steel Institute.

Includes section "A survey of literature on the manufacture and properties of iron and steel, and kindred subjects" (title varies)

The National Institutes of Health research and research related manpower development programs : college opportunities.

Shipping list no.: 89-752-P.

The adventures of Downy V. Green : Rhodes scholar at Oxford /

Murray file copy no. 251.

The national defense graduate fellowship program; a manual for participating graduate schools.

Cover title.

Annual report / Illinois State Scholarship Commission.

Description based on: 1986; title from cover.

Annual survey /

Mode of access: Internet.

Illinois Podiatric Scholarship and Residency Act summary report /

Cover title.

Program information manual : monetary awards, 1973-74 /

Mode of access: Internet.