1000 resultados para população controle


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Objetivo:O objetivo deste estudo foi investigar o fenótipo do HLA em pacientes com contratura de Dupuytren (CD) para verificar a correlação desses alelos com os fatores de risco para o desenvolvimento da CD na população brasileira.Métodos:Este foi um estudo de caso-controle de 25 pacientes com CD e 443 indivíduos saudáveis sem histórico de doenças associadas ao HLA. As tipagens classe I e classe II do HLA foram feitas utilizando o método iniciador de sequências específicas da reação em cadeia da polimerase.Resultados:O fenótipo HLA-B*18 foi observado em 32% dos pacientes e 10,5% do grupo controle. Contudo, os valores de p não permaneceram significativos após correção.Discussão:Apesar de termos observado um aumento na tendência de os pacientes com CD terem o alelo HLA-B*18, os resultados não foram estatisticamente significativos após correção. Esse alelo foi maior em pacientes de etnia italiana e/ou espanhola, locais com frequências superiores a 18% e 14%, respectivamente. São necessárias investigações adicionais com uma coorte maior de pacientes com CD para confirmar o possível papel do HLA nessa doença.

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The objective of this experiment was to evaluate the effects of corn hybrid cultivation and weed control periods on the population and growth of the weeds B. plantaginea and R. raphanistrum. The trial was set at Universidade Estadual the São Paulo (UNESP), Botucatu Campus, São Paulo - Brazil. A completely randomized block design with four replications was used. The treatments were arranged in a factorial scheme with four corn hybrids (C701, DINA170, XL678, and C125) and four manual weed control periods [a. 15 days after emergence (DAE); b. 15 and 30 DAE; c. 15, 30 and 45 DAE, and d. weedy]. The hybrids DINA170 and C125 significantly decreased the density of B. plantaginea. The hybrids C701, DINA170 and XL678 affected the growth of the plants, but they did not affect the emergence of new plants of R. raphanistrum. Hand-hoeing at 15 DAE decreased the dry matter weight of the weeds B. lantaginea and R. raphanistrum by 93.1%, 95.4% and 89.2%, respectively, at harvest of the four hybrids.

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Pós-graduação em Biometria - IBB

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O objetivo deste estudo foi avaliar o desempenho dos sistemas sensoriais e do controle postural de idosos diabéticos e investigar a relação entre as alterações destes sistemas e do controle postural desta população. Participaram deste estudo dez idosos diabéticos ativos (62±4,4 anos) (GDA), 10 diabéticos sedentários (65,5±7,4 anos) (GDS) e 10 idosos saudáveis ativos (63,2±4.5anos) (GCA) foram submetidos a avaliações sensoriais e de controle postural. As avaliações sensoriais foram compostas por avaliação somatossensorial (sensibilidade cutânea e sensibilidade ao movimento passivo). Para avaliar o controle postural foram analisadas medidas de oscilação corporal durante manutenção da postura ereta (em tandem stance e bipodal). Os resultados indicaram pior desempenho do GDS na avaliação do movimento passivo e de controle postural. Nas avaliações de controle postural, o GDS apresentou uma maior amplitude média de oscilação (AMO) (cm) nas condições de manutenção da postura ereta na posição tandem stance na direção médio-lateral. No teste de sensibilidade ao movimento passivo, o GDS precisou, em média, de um maior deslocamento angular para perceber o movimento das articulações do joelho e tornozelo. Estes resultados indicam, portanto, que as alterações estruturais e fisiológicas decorrentes do diabetes, resultam em piora do desempenho dos sistemas sensoriais e de controle postural. Além disso, a maior deterioração do sistema proprioceptivo em idosos diabéticos pode interferir negativamente no desempenho de controle postural dos mesmos. Desta forma, a atividade física minimiza a perda sensorial e ainda ajuda no controle postural dos diabéticos.

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Pós-graduação em Agronomia (Genética e Melhoramento de Plantas) - FCAV

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Objective: The aim of this study was to develop an educational oral health digital game for 5-to-7-year-old children. Method: The game, called “Dr. Trata Dente”, was based on the approach to three different oral health-related topics: a) bacterial plaque and the main diseases caused by it; b) oral hygiene methods for bacterial plaque control; c) dental caries and preventive measures for this disease. These topics were discussed in sequential order in three different stages of the game. Dr. Trata Dente is represented by the figure of a little super-hero dentist, who talks to the children about oral health during the game. The game is sub-divided according to its propositions to the children, into an association game, a memory game and a coloring game. After its development, the game was evaluated by three professionals of each of the following areas: Dentistry, Pedagogy and Psychology (n=9), who verified the suitability of the concepts presented in the game as regards oral health, linguistic abilities worked with the children, fulfillment of the intended didactic criteria, and the playful aspect of the game. Results: According to the dentists, the dental concepts presented in the game are adequate. According to the pedagogues, the choice of a super-hero was correct and the given explanations are well elaborated, organized and have accessible language, although long. For the psychologists, the game has a potential positive effect on the children’s learning, but there should be more interaction of the character with the children. After this evaluation, changes were made in the game according to the professionals’ suggestions. Conclusion: It was concluded that in spite of the suggested alterations, the game is suitable for teaching oral health by means of children’s play.

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Pós-graduação em Agronomia (Produção Vegetal) - FCAV

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Individuals with Parkinson's disease (PD) seem to present asymmetric postural control, and the commitment to postural control that is a big factor of falls in this population. However, the asymmetry in the postural control of fallers and non fallers with PD and neurologically healthy elderly is not too much studied. The objective of the study is to analyze the asymmetry in postural control in different static positions of elderly patients with PD and healthy elderly fallers and non fallers. The study included 70 older adults with PD and 70 neurologically healthy (CG). The groups were matched for age, gender, height, weight and cognitive condition. It was evaluated the clinical, cognitive status and incidence of falls among its participants through weekly prospective follow-up of 4 months. Then, for each group, CG and PD, it was selected 12 elderly fallers and 12 elderly non fallers to evaluate postural control. Participants were evaluated through two force platforms in conditions of bipedal support, unipedal and tandem position. It was realized 3 attempts of 30s for each condition. For unipedal and tandem condition it was made 3 attempts for each lower limb. The parameters of interest of the center of pressure (CoP), were analyzed for each condition and compared by MANOVAs with factor group, fall and asymmetry. Post hoc Tukey tests were used to determine the relationships between them. The results show that CG individuals showed greater velocity and CoP area in relation to PD. It was verified that at the control group that non fallers individuals (CGN) had more displacement and RMS in the average lateral direction in the dominant limb when compared to the less affected limb of non fallers with PD (PDN). Faller individuals in the control group (CGF) had larger area in the non dominant limb when compared to the most affected leg of fallers individuals with PD (PDF). Still, the PDF individuals had higher RMS in anteroposterior feeling....

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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The aim of this work was to compare the efficiency of conventional antibiotics in relation to hop-based antimicrobials, in industrial-scale bioethanol production. The comparison was made by calculating the lactic acid bacteria population reduction in two consecutive fermentation cycles. To conduct the experiment, it was used five treatments (three conventional antibiotics: Kamoran WP, Corstan and Alcapen 1030, and two hop-based antimicrobials: BetaBio and IsoStab). The samples were collected in the fermentation vat. In order to quantify the initial lactic acid bacteria population, a sample was collected at the end of the fermentation process (wine) before the treatment with antibiotics or antimicrobials, and to determine the final population, another sample was collected at the end of the fermentation process (wine) after the treatment with antibiotics or antimicrobials. The experiment was completely randomized and the statistical analysis was performed through analysis of variance (ANOVA) for data processed using the equation y’ = . After the data transformation, the Levene's test was applied to verify data adherence to normal distribution, and the averages were compared through Tukey’s test at 5% probability. The results showed that the hop-based antimicrobials (IsoStab and BetaBio) can be used to substitute the conventional antibiotics (Kamoran, Alcapen and Corstan), since there was no statistical difference between the treatments.